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The map label for this gene is minC [H]

Identifier: 161870893

GI number: 161870893

Start: 2035897

End: 2036643

Strand: Reverse

Name: minC [H]

Synonym: NMCC_1982

Alternate gene names: 161870893

Gene position: 2036643-2035897 (Counterclockwise)

Preceding gene: 161870894

Following gene: 161870892

Centisome position: 94.58

GC content: 44.44

Gene sequence:

>747_bases
TTGCGCGGTAAACTTACATCATTAAAAAATTCTATGATGGTTTATATAATGAATGCTTTCGATATAAAGTCGACAAAGAT
GGACGTATTGTCTATATCTTTGCATACGTCAGACTTGTTTGATTTGGAAGATGTGCTGGTCAAATTGGGCAAGAAGTTTC
AAGAGTCTGGTGTTGTTCCATTTGTGCTGGATGTTCAAGAGTTTGATTATCCCGAGTCTTTGGATCTTGCTGCATTGGTT
TCGTTGTTTTCAAGGCATGGTATGCAAATTTTGGGTCTGAAGCATTCTAATGAACGTTGGGCTGCTGCGGCTATGAAGTA
TCATTTGCTGTTTTGTCTGTCTCATTCGGAAAATGTTAAAGAACTGGGTCAGGTTGAGGTGCAGAACACGGAGGATGGTC
AGAAAGCAAGGAAAACAGTATTGATTACATCCCCTGTCCGTACCGGTCAGCAGGTTTATGCCGAAGATGGCGATTTGATT
GTTACGGGGGCGGTCAGCCAGGGGGCGGAATTGATTGCGGATGGCAATATACATATTTATGCGCCGATGAGGGGGCGTGC
TTTGGCCGGTGCCAAGGGTGATACTTCTGCCCGCATATTTATCCACTCCATGCAGGCAGAACTGGTTTCTGTGGCGGGTA
TTTACCGTAATTTTGAACAGGATTTGCCGAACCATCTGCACAAGCAGCCGGTACAGATATTGTTGCAGGATAACCGATTG
GTTATCAGTGCAATTGGCTCAGAGTAA

Upstream 100 bases:

>100_bases
ACGCCATCTGCCGAAAAGCAGGTGGCGTTATTTTTGCAATATCTGATAGGTAATAGGGTATTGGCTATCATGTTTAAAAT
ATTAATTGAATAGCTAAGGT

Downstream 100 bases:

>100_bases
TTGTTTGATATTTTAAAAGGAAATATTGTGGCAAAAATTATTGTAGTAACTTCAGGTAAGGGCGGTGTCGGTAAAACGAC
TACCAGTGCCAGTATTGCGA

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRGKLTSLKNSMMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQESGVVPFVLDVQEFDYPESLDLAALV
SLFSRHGMQILGLKHSNERWAAAAMKYHLLFCLSHSENVKELGQVEVQNTEDGQKARKTVLITSPVRTGQQVYAEDGDLI
VTGAVSQGAELIADGNIHIYAPMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPNHLHKQPVQILLQDNRL
VISAIGSE

Sequences:

>Translated_248_residues
MRGKLTSLKNSMMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQESGVVPFVLDVQEFDYPESLDLAALV
SLFSRHGMQILGLKHSNERWAAAAMKYHLLFCLSHSENVKELGQVEVQNTEDGQKARKTVLITSPVRTGQQVYAEDGDLI
VTGAVSQGAELIADGNIHIYAPMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPNHLHKQPVQILLQDNRL
VISAIGSE
>Mature_248_residues
MRGKLTSLKNSMMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQESGVVPFVLDVQEFDYPESLDLAALV
SLFSRHGMQILGLKHSNERWAAAAMKYHLLFCLSHSENVKELGQVEVQNTEDGQKARKTVLITSPVRTGQQVYAEDGDLI
VTGAVSQGAELIADGNIHIYAPMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPNHLHKQPVQILLQDNRL
VISAIGSE

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=190, Percent_Identity=37.8947368421053, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 27424; Mature: 27424

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGKLTSLKNSMMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQESGVVP
CCCCHHHHCCCEEEEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCE
FVLDVQEFDYPESLDLAALVSLFSRHGMQILGLKHSNERWAAAAMKYHLLFCLSHSENVK
EEEEHHHCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHEEEEEEECCCCCHH
ELGQVEVQNTEDGQKARKTVLITSPVRTGQQVYAEDGDLIVTGAVSQGAELIADGNIHIY
HHCCEEEECCCCCHHHCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCCEEEE
APMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPNHLHKQPVQILLQDNRL
ECCCCCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEE
VISAIGSE
EEEECCCC
>Mature Secondary Structure
MRGKLTSLKNSMMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQESGVVP
CCCCHHHHCCCEEEEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCE
FVLDVQEFDYPESLDLAALVSLFSRHGMQILGLKHSNERWAAAAMKYHLLFCLSHSENVK
EEEEHHHCCCCCCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHEEEEEEECCCCCHH
ELGQVEVQNTEDGQKARKTVLITSPVRTGQQVYAEDGDLIVTGAVSQGAELIADGNIHIY
HHCCEEEECCCCCHHHCEEEEEECCCCCCCEEEECCCCEEEEECCCCCCEEEECCCEEEE
APMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPNHLHKQPVQILLQDNRL
ECCCCCEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEE
VISAIGSE
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11160816 [H]