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The map label for this gene is minD

Identifier: 161870892

GI number: 161870892

Start: 2035054

End: 2035869

Strand: Reverse

Name: minD

Synonym: NMCC_1981

Alternate gene names: 161870892

Gene position: 2035869-2035054 (Counterclockwise)

Preceding gene: 161870893

Following gene: 161870891

Centisome position: 94.54

GC content: 46.69

Gene sequence:

>816_bases
GTGGCAAAAATTATTGTAGTAACTTCAGGTAAGGGCGGTGTCGGTAAAACGACTACCAGTGCCAGTATTGCGACAGGTTT
GGCATTACGCGGATATAAAACTGCGGTAATTGATTTTGATGTGGGCTTGCGTAACCTCGACCTCATTATGGGTTGTGAGC
GTCGTGTCGTTTATGACCTGATCAATGTCATTCAGGGGGAGGCGACGCTCAACCAAGCTTTGATTAAAGATAAAAATTGT
GAAAACCTGTTTATTTTGCCGGCTTCCCAGACTCGGGATAAAGACGCTTTGACACGCGAGGGCGTAGAAAAAGTGATGCA
GGAGCTGTCCGGCAAGAAAATGGGCTTTGAGTATATTATTTGCGACTCTCCTGCCGGTATTGAGCAGGGTGCATTGATGG
CGTTGTATTTTGCTGATGAAGCCATTGTAACGACCAATCCTGAGGTTTCCAGTGTGCGTGACTCCGACAGGATTTTGGGA
ATTTTGCAAAGCAAATCCCATAAGGCAGAGCAAGGCGGTTCGGTTAAAGAACATCTGTTGATTACGCGTTATTCTCCCGA
ACGAGTGGCAAAAGGCGAAATGCTGTCTGTACAGGATATTTGCGATATTCTGCATATTCCTTTGCTGGGTGTGATTCCTG
AATCCCAAAACGTCTTGCAGGCATCCAATTCCGGAGAACCGGTCATCCATCAGGACAGCGTGGCGGCTTCCGAGGCATAT
AAGGACGTTATTGCCCGTCTTTTGGGCGAGAACCGTGAAATGCGTTTCTTGGAAGCTGAGAAAAAAAGCTTCTTCAAACG
TCTGTTTGGAGGATAA

Upstream 100 bases:

>100_bases
TCTGCACAAGCAGCCGGTACAGATATTGTTGCAGGATAACCGATTGGTTATCAGTGCAATTGGCTCAGAGTAATTGTTTG
ATATTTTAAAAGGAAATATT

Downstream 100 bases:

>100_bases
GGTATGTCATTAATCGAATTTTTATTCGGCAGAAAGCAGAAAACGGCAACCGTTGCCCGCGACCGCCTTCAAATCATCAT
TGCCCAAGAGCGCGCCCAAG

Product: septum site-determining protein

Products: NA

Alternate protein names: Cell division inhibitor minD

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIQGEATLNQALIKDKNC
ENLFILPASQTRDKDALTREGVEKVMQELSGKKMGFEYIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILG
ILQSKSHKAEQGGSVKEHLLITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNVLQASNSGEPVIHQDSVAASEAY
KDVIARLLGENREMRFLEAEKKSFFKRLFGG

Sequences:

>Translated_271_residues
MAKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIQGEATLNQALIKDKNC
ENLFILPASQTRDKDALTREGVEKVMQELSGKKMGFEYIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILG
ILQSKSHKAEQGGSVKEHLLITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNVLQASNSGEPVIHQDSVAASEAY
KDVIARLLGENREMRFLEAEKKSFFKRLFGG
>Mature_270_residues
AKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIQGEATLNQALIKDKNCE
NLFILPASQTRDKDALTREGVEKVMQELSGKKMGFEYIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGI
LQSKSHKAEQGGSVKEHLLITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNVLQASNSGEPVIHQDSVAASEAYK
DVIARLLGENREMRFLEAEKKSFFKRLFGG

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily

Homologues:

Organism=Escherichia coli, GI1787423, Length=272, Percent_Identity=73.8970588235294, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): MIND_NEIMB (Q7DDS7)

Other databases:

- EMBL:   AE002098
- PIR:   C81230
- RefSeq:   NP_273229.1
- ProteinModelPortal:   Q7DDS7
- SMR:   Q7DDS7
- EnsemblBacteria:   EBNEIT00000009496
- GeneID:   902278
- GenomeReviews:   AE002098_GR
- KEGG:   nme:NMB0171
- TIGR:   NMB0171
- GeneTree:   EBGT00050000021823
- HOGENOM:   HBG691818
- OMA:   LAMHFAD
- ProtClustDB:   CLSK877410
- BioCyc:   NMEN122586:NMB_0171-MONOMER
- InterPro:   IPR002586
- InterPro:   IPR010223
- TIGRFAMs:   TIGR01968

Pfam domain/function: PF01656 CbiA

EC number: NA

Molecular weight: Translated: 29559; Mature: 29428

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLRNLDLIMGCERRVVYDL
CEEEEEEECCCCCCCCCCCCHHHHHHHEECCCEEEEEEECCCCCHHHHHHCCCHHHHHHH
INVIQGEATLNQALIKDKNCENLFILPASQTRDKDALTREGVEKVMQELSGKKMGFEYII
HHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
CDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGILQSKSHKAEQGGSVKEHLL
ECCCCCCCCCCEEEEEEECCEEEECCCCHHHCCCCHHHEEHHHCCCCCHHCCCCHHHEEE
ITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNVLQASNSGEPVIHQDSVAASEAY
EEECCHHHHCCCCEECHHHHHHHHHHCHHEECCCCCCCEECCCCCCCEEECCCHHHHHHH
KDVIARLLGENREMRFLEAEKKSFFKRLFGG
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLRNLDLIMGCERRVVYDL
EEEEEEECCCCCCCCCCCCHHHHHHHEECCCEEEEEEECCCCCHHHHHHCCCHHHHHHH
INVIQGEATLNQALIKDKNCENLFILPASQTRDKDALTREGVEKVMQELSGKKMGFEYII
HHHHCCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
CDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILGILQSKSHKAEQGGSVKEHLL
ECCCCCCCCCCEEEEEEECCEEEECCCCHHHCCCCHHHEEHHHCCCCCHHCCCCHHHEEE
ITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNVLQASNSGEPVIHQDSVAASEAY
EEECCHHHHCCCCEECHHHHHHHHHHCHHEECCCCCCCEECCCCCCCEEECCCHHHHHHH
KDVIARLLGENREMRFLEAEKKSFFKRLFGG
HHHHHHHHCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10710307