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The map label for this gene is frr [H]

Identifier: 161870876

GI number: 161870876

Start: 2016244

End: 2016870

Strand: Direct

Name: frr [H]

Synonym: NMCC_1965

Alternate gene names: 161870876

Gene position: 2016244-2016870 (Clockwise)

Preceding gene: 161870875

Following gene: 161870877

Centisome position: 93.63

GC content: 54.07

Gene sequence:

>627_bases
ATGCCGTCTGAACGGCTTGAAACGCGTTCAGACGGTCTCCCGCCCACCTTATCCCACCGAAAGAACAATATGATCAACGA
TATTCAAAAAACAGCCGAAGGCAAAATGCAGCGTTCGGTCGAAGTACTGAAAGAAAATCTGGCGAAAGTGCGTACCGGCC
GCGCGCATACCGGCCTGCTCGACCAAGTGGAAGTCGAATACTGGGGCAGCATGGTCCCCGTCAGCCAAGTTGCCAACGTA
ACGCTTCTGGACGCGCGCACCATCGGCGTGAAACCGTTTGAGGGCAATATGGCGGTCAAAGTCGAGAAAGCCATCCGCGA
TTCAAACTTGGGGCTGAACCCGGCAGCTGTCGGCGACCTGATCCGCGTGCCGATGCCCATGCTGACCGAAGAACGCCGCA
AAGACCTGATTAAAGTCGTACGCGGCGAAGCGGAAGAAGGCCGCGTCTCTATCCGCAACGTGCGCCGCGATGCCAACGAC
CACATCAAAAAACTCCTCAAAGACAAAGAAATTTCCGAAGACGAGGCACGTCGCGGCGAAGAAGCGGTTCAAAAACTGAC
CGACAAATACATTACCGAAGCCGACAAACTCCTGACTGCCAAAGAAGAAGATTTGATGGCAATTTAA

Upstream 100 bases:

>100_bases
CGATGCCGTCTGAAACGCCTGTCGCTTCAGACGGCATCCCCAATCCGCCTACCTTGTCGTTATGCCCGAATAACGGTACT
ATTCGCGGTTAACGGTCTTT

Downstream 100 bases:

>100_bases
CCTGCACGGTTCGGCGTTCAGACGGCATTTGAATGCCGAACCGCGAAAGGCAGACATGAAAAGCAGCACGCAGGCCGTTT
TGGAACACACCGCCATTCCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPSERLETRSDGLPPTLSHRKNNMINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLLDQVEVEYWGSMVPVSQVANV
TLLDARTIGVKPFEGNMAVKVEKAIRDSNLGLNPAAVGDLIRVPMPMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDAND
HIKKLLKDKEISEDEARRGEEAVQKLTDKYITEADKLLTAKEEDLMAI

Sequences:

>Translated_208_residues
MPSERLETRSDGLPPTLSHRKNNMINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLLDQVEVEYWGSMVPVSQVANV
TLLDARTIGVKPFEGNMAVKVEKAIRDSNLGLNPAAVGDLIRVPMPMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDAND
HIKKLLKDKEISEDEARRGEEAVQKLTDKYITEADKLLTAKEEDLMAI
>Mature_207_residues
PSERLETRSDGLPPTLSHRKNNMINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLLDQVEVEYWGSMVPVSQVANVT
LLDARTIGVKPFEGNMAVKVEKAIRDSNLGLNPAAVGDLIRVPMPMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDANDH
IKKLLKDKEISEDEARRGEEAVQKLTDKYITEADKLLTAKEEDLMAI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=173, Percent_Identity=30.635838150289, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI291042689, Length=151, Percent_Identity=31.7880794701987, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=56.2841530054645, Blast_Score=205, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=31.4285714285714, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 23377; Mature: 23246

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSERLETRSDGLPPTLSHRKNNMINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLL
CCCCHHCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DQVEVEYWGSMVPVSQVANVTLLDARTIGVKPFEGNMAVKVEKAIRDSNLGLNPAAVGDL
HHHHHHHCCCCCCHHHHCCEEEEECEECCCCCCCCCEEEEHHHHHHHCCCCCCHHHHHHH
IRVPMPMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDANDHIKKLLKDKEISEDEARRGE
HHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
EAVQKLTDKYITEADKLLTAKEEDLMAI
HHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
PSERLETRSDGLPPTLSHRKNNMINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLL
CCCHHCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
DQVEVEYWGSMVPVSQVANVTLLDARTIGVKPFEGNMAVKVEKAIRDSNLGLNPAAVGDL
HHHHHHHCCCCCCHHHHCCEEEEECEECCCCCCCCCEEEEHHHHHHHCCCCCCHHHHHHH
IRVPMPMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDANDHIKKLLKDKEISEDEARRGE
HHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
EAVQKLTDKYITEADKLLTAKEEDLMAI
HHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA