| Definition | Neisseria meningitidis 053442, complete genome. |
|---|---|
| Accession | NC_010120 |
| Length | 2,153,416 |
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The map label for this gene is rne [H]
Identifier: 161870864
GI number: 161870864
Start: 2002096
End: 2004855
Strand: Direct
Name: rne [H]
Synonym: NMCC_1952
Alternate gene names: 161870864
Gene position: 2002096-2004855 (Clockwise)
Preceding gene: 161870858
Following gene: 161870868
Centisome position: 92.97
GC content: 59.28
Gene sequence:
>2760_bases ATGAAAAGAATGTTATTTAACGCAACGCAGGCCGAAGAGCTGCGCGTTGCCATCGTCGACGGACAAAACCTGCTGGATTT GGACATCGAAACGCTGGGCAAAGAACAGCGCAAAGGCAATATCTACAAAGGCATCATTACCCGCATCGAGCCGTCGCTGG AAGCGTGTTTCGTGGATTACGGAACCGACCGCCACGGCTTCTTGCCGTTTAAAGAAGTCTCCCGCTCATACTTCCAAGAC TACGAAGGCGGACGCGCGCGCATCCAAGACGTGCTCAAAGAAGGCATGGAAGTCATCGTCCAAGTCGAAAAAGACGAGCG CGGCAACAAAGGCGCCGCGCTGACCACCTTCATCAGCCTCGCCGGACGCTATCTGGTATTGATGCCGAACAACCCGCGCG GCGGCGGCGTATCCCGCCGTATCGAAGGTGAAGAGCGTCAAGAGTTGAAAGCCGCCATGGCGGAACTCGACATTCCGAAC GGCATGAGCATCATCGCCCGTACCGCCGGCATCGGCCGCAGCGCGGAAGAGTTGGAATGGGACTTGAACTACCTCAAACA ACTCTGGCAGGCGATTGAAGAAGCAGGAAAAGCGCATCACGACCCCTACCTGCTCTTTATGGAAAGCTCGCTGCTGATCC GAGCCATCCGCGACTATTTCCGCCCCGACATCGGCGAGATTTTGGTGGACAATCAAGAAGTTTACGACCAAGTTGCCGAG TTCATGAGCTACGTCATGCCGGGCAATATAGGCCGTCTGAAACTCTACGAAGACCACACGCCGCTGTTTTCCCGCTTCCA AATCGAACATCAAATCGAAAGCGCGTTTTCGCGCAGCGTCAGCCTGCCTTCCGGCGGCGCGATCGTGATCGACCACACCG AAGCCCTCGTTTCCATCGACGTGAACTCCGCACGCGCCACACGCGGCGCGGACATCGAAGACACCGCGTTCAAAACCAAT ATGGAAGCCGCCGAAGAAGTCGCCCGACAAATGCGCCTGCGCGACTTGGGCGGTTTGGTCGTCATCGACTTCATCGATAT GGAAAACCCCAAACACCAGCGCGATGTGGAAAACGTCCTGCGCGACGCGCTCAAAAAAGACCGCGCCCGCGTGCAGATGG GCAAACTGTCCCGTTTCGGACTTTTAGAATTGAGCCGCCAACGTTTGAAACCGGCTTTGGGCGAAAGCAGCCATGTTGCG TGTCCGCGCTGTGCCGGCACCGGCGTGATTCGGGGCATCGAATCCACCGCCCTGCACGTTTTGCGCATCATTCAAGAAGA AGCAATGAAAGACAACACCGGCGAAGTGCGCGCACAAGTGCCCGTCGATGTCGCCACCTTCCTGCTGAACGAAAAACGCG CCGAGCTGTTTGCGATGGAAGAGCGTTTGGATGTCAACGTCGTCCTGATTCCGAACATCCACCTCGAAAATCCGCACTAC GAAATCAACCGCATCCGCACCGACGACGTAGAAGAAGACGGCGAACCGAGCTACAAGCGCGTTGCCGAGCCAGAAGAAGA CGAATCCGCCAAACCGTTCGGCGGCGAAAAAGCCAAAGCCGCCCGTCCCGAACCCGCCGTCAAAGGCGTGCGCCACACCA GCCCCGCCCCGACTGCCGCCCCCGAGAAAAAAACCTCCTGGTGGGACAGCTTCAAAGCTTGGCTCAAACGCATTTTCGGC GGCAGCGAAACCCAAGCCGCACCCGCTGCCGAAACCTCCGAAAAACGCAGCACGGCAAACCGCAGCGGCAGCCGCGCCAA CAACCGCCGCCAAAACCCGCGCCGCAGCAAACGCGAAGGCAGCAAAGTAGAAGTCCGCGAAGTGGCAGGCAAAACTGCCA GACAGGAAGCGCGTGCCGACACAGCCGAAACGCGCAACAACGGCAACCGCCGCCGCAACGAACGCGGCGACCGTGCCGCC GAACGTGCCAACGAAGCGGAAATCCAAAGCCGCAACGTACAGCCTGCCGCAACCGTTGCAGATGCCGCACCGTCCGAAAC CGAAGTGCAAACCGGAAAACGCCGCCGCAACGGCAGCCGCAACGAACGCGGCCAAACCGCGCCGGAAACCGCCGCCGTTG CCGAAACAGCCGTTCAGACAGCGGAAAACACGCCGTCCGAACCGCATACCGCAGAAGACAAAGGCAGCAAGCCCAAATCC GAACGCAACCGCCGCGAACGCGACAGCCGCGACGCCAAAGAACGCCGCGAGCGCAACAATCAGCGCGACCGCCGTCAAAA CGGCAAAAAACGCAATATTCCGTCTGCCGCCAAAATCGAGCAGTACCTGAATATTCACGACACCGCCGACAAAGTCCATT CCGCCGCCGCGCACGTTTTCGGCGAAACCGACGCAAACGCGCCGATTACCGTCAGCATTGCCGATCCGGTTGCAGAAAGG GATCTTCCGACAGCATCTCCCGCCGTTTCAAACGGCGACGCACCGGTTTATGATGCGGCGGAAAAAATCCGCCGTGCCAC CGCCGCCATCCTGCCCGAAGGCGCGACACCGAAAGCCGAAGCACAGGAAATGCCGTCTGAAACCGCAACCTTTACGGCTG CGGCGGAACAGGCACGGGAAACCGCACAAACCGGCGGACTCGTCCTGATCGAAACCGACCCTGCCGCATTGAAGGCATGG GCGGCACAACCCGAAGTCCAAACCGGACGCGGTTTGCGCCGTTCCGAACAGCCCAAGCCGTCTGAAGTCGCAACCGTCCC TGCCGAAGAAATGATCCAAGTCGAAACCCGGCAAGGCTGA
Upstream 100 bases:
>100_bases AACTGATTACCGGTTTTATCCGAAAACATCGGAAAACCAGCCTTACGGAATGCCGAACCGGGCATGTGCCGTCTGAACGC CGCCTGCCCACGAGGTGATC
Downstream 100 bases:
>100_bases ACCGACGGCGGCAAAAAGAGGTTCTGTTCCGCAGAACCTCTTTTTTATATAGATTCGGATACCTGCAATGCCGTCTGAAG CCTCACCATTCCCATGATTA
Product: ribonuclease E
Products: NA
Alternate protein names: RNase E [H]
Number of amino acids: Translated: 919; Mature: 919
Protein sequence:
>919_residues MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKGIITRIEPSLEACFVDYGTDRHGFLPFKEVSRSYFQD YEGGRARIQDVLKEGMEVIVQVEKDERGNKGAALTTFISLAGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAELDIPN GMSIIARTAGIGRSAEELEWDLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRDYFRPDIGEILVDNQEVYDQVAE FMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAFSRSVSLPSGGAIVIDHTEALVSIDVNSARATRGADIEDTAFKTN MEAAEEVARQMRLRDLGGLVVIDFIDMENPKHQRDVENVLRDALKKDRARVQMGKLSRFGLLELSRQRLKPALGESSHVA CPRCAGTGVIRGIESTALHVLRIIQEEAMKDNTGEVRAQVPVDVATFLLNEKRAELFAMEERLDVNVVLIPNIHLENPHY EINRIRTDDVEEDGEPSYKRVAEPEEDESAKPFGGEKAKAARPEPAVKGVRHTSPAPTAAPEKKTSWWDSFKAWLKRIFG GSETQAAPAAETSEKRSTANRSGSRANNRRQNPRRSKREGSKVEVREVAGKTARQEARADTAETRNNGNRRRNERGDRAA ERANEAEIQSRNVQPAATVADAAPSETEVQTGKRRRNGSRNERGQTAPETAAVAETAVQTAENTPSEPHTAEDKGSKPKS ERNRRERDSRDAKERRERNNQRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVHSAAAHVFGETDANAPITVSIADPVAER DLPTASPAVSNGDAPVYDAAEKIRRATAAILPEGATPKAEAQEMPSETATFTAAAEQARETAQTGGLVLIETDPAALKAW AAQPEVQTGRGLRRSEQPKPSEVATVPAEEMIQVETRQG
Sequences:
>Translated_919_residues MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKGIITRIEPSLEACFVDYGTDRHGFLPFKEVSRSYFQD YEGGRARIQDVLKEGMEVIVQVEKDERGNKGAALTTFISLAGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAELDIPN GMSIIARTAGIGRSAEELEWDLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRDYFRPDIGEILVDNQEVYDQVAE FMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAFSRSVSLPSGGAIVIDHTEALVSIDVNSARATRGADIEDTAFKTN MEAAEEVARQMRLRDLGGLVVIDFIDMENPKHQRDVENVLRDALKKDRARVQMGKLSRFGLLELSRQRLKPALGESSHVA CPRCAGTGVIRGIESTALHVLRIIQEEAMKDNTGEVRAQVPVDVATFLLNEKRAELFAMEERLDVNVVLIPNIHLENPHY EINRIRTDDVEEDGEPSYKRVAEPEEDESAKPFGGEKAKAARPEPAVKGVRHTSPAPTAAPEKKTSWWDSFKAWLKRIFG GSETQAAPAAETSEKRSTANRSGSRANNRRQNPRRSKREGSKVEVREVAGKTARQEARADTAETRNNGNRRRNERGDRAA ERANEAEIQSRNVQPAATVADAAPSETEVQTGKRRRNGSRNERGQTAPETAAVAETAVQTAENTPSEPHTAEDKGSKPKS ERNRRERDSRDAKERRERNNQRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVHSAAAHVFGETDANAPITVSIADPVAER DLPTASPAVSNGDAPVYDAAEKIRRATAAILPEGATPKAEAQEMPSETATFTAAAEQARETAQTGGLVLIETDPAALKAW AAQPEVQTGRGLRRSEQPKPSEVATVPAEEMIQVETRQG >Mature_919_residues MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKGIITRIEPSLEACFVDYGTDRHGFLPFKEVSRSYFQD YEGGRARIQDVLKEGMEVIVQVEKDERGNKGAALTTFISLAGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAELDIPN GMSIIARTAGIGRSAEELEWDLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRDYFRPDIGEILVDNQEVYDQVAE FMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAFSRSVSLPSGGAIVIDHTEALVSIDVNSARATRGADIEDTAFKTN MEAAEEVARQMRLRDLGGLVVIDFIDMENPKHQRDVENVLRDALKKDRARVQMGKLSRFGLLELSRQRLKPALGESSHVA CPRCAGTGVIRGIESTALHVLRIIQEEAMKDNTGEVRAQVPVDVATFLLNEKRAELFAMEERLDVNVVLIPNIHLENPHY EINRIRTDDVEEDGEPSYKRVAEPEEDESAKPFGGEKAKAARPEPAVKGVRHTSPAPTAAPEKKTSWWDSFKAWLKRIFG GSETQAAPAAETSEKRSTANRSGSRANNRRQNPRRSKREGSKVEVREVAGKTARQEARADTAETRNNGNRRRNERGDRAA ERANEAEIQSRNVQPAATVADAAPSETEVQTGKRRRNGSRNERGQTAPETAAVAETAVQTAENTPSEPHTAEDKGSKPKS ERNRRERDSRDAKERRERNNQRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVHSAAAHVFGETDANAPITVSIADPVAER DLPTASPAVSNGDAPVYDAAEKIRRATAAILPEGATPKAEAQEMPSETATFTAAAEQARETAQTGGLVLIETDPAALKAW AAQPEVQTGRGLRRSEQPKPSEVATVPAEEMIQVETRQG
Specific function: Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by
COG id: COG1530
COG function: function code J; Ribonucleases G and E
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 S1 motif domain [H]
Homologues:
Organism=Escherichia coli, GI1787325, Length=532, Percent_Identity=60.5263157894737, Blast_Score=654, Evalue=0.0, Organism=Escherichia coli, GI87082235, Length=429, Percent_Identity=38.4615384615385, Blast_Score=251, Evalue=2e-67,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR021968 - InterPro: IPR003029 - InterPro: IPR019307 - InterPro: IPR022967 - InterPro: IPR004659 [H]
Pfam domain/function: PF12111 PNPase_C; PF10150 RNase_E_G; PF00575 S1 [H]
EC number: =3.1.26.12 [H]
Molecular weight: Translated: 101987; Mature: 101987
Theoretical pI: Translated: 6.17; Mature: 6.17
Prosite motif: PS50126 S1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKGIITRIEPSLEACFVDY CCCCCCCCCCCCCEEEEEECCCCEEECCHHHHCCHHHCCCHHHHHHHHHCCCHHHEEEEC GTDRHGFLPFKEVSRSYFQDYEGGRARIQDVLKEGMEVIVQVEKDERGNKGAALTTFISL CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH AGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAELDIPNGMSIIARTAGIGRSAEELEW HCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHH DLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRDYFRPDIGEILVDNQEVYDQVAE HHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHH FMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAFSRSVSLPSGGAIVIDHTEALVSID HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEE VNSARATRGADIEDTAFKTNMEAAEEVARQMRLRDLGGLVVIDFIDMENPKHQRDVENVL CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHH RDALKKDRARVQMGKLSRFGLLELSRQRLKPALGESSHVACPRCAGTGVIRGIESTALHV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH LRIIQEEAMKDNTGEVRAQVPVDVATFLLNEKRAELFAMEERLDVNVVLIPNIHLENPHY HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEECCCCE EINRIRTDDVEEDGEPSYKRVAEPEEDESAKPFGGEKAKAARPEPAVKGVRHTSPAPTAA EEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC PEKKTSWWDSFKAWLKRIFGGSETQAAPAAETSEKRSTANRSGSRANNRRQNPRRSKREG CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCC SKVEVREVAGKTARQEARADTAETRNNGNRRRNERGDRAAERANEAEIQSRNVQPAATVA CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHH DAAPSETEVQTGKRRRNGSRNERGQTAPETAAVAETAVQTAENTPSEPHTAEDKGSKPKS CCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH ERNRRERDSRDAKERRERNNQRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVHSAAAHVF HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH GETDANAPITVSIADPVAERDLPTASPAVSNGDAPVYDAAEKIRRATAAILPEGATPKAE CCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH AQEMPSETATFTAAAEQARETAQTGGLVLIETDPAALKAWAAQPEVQTGRGLRRSEQPKP HHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCCCHHCCCCCCCCCCCC SEVATVPAEEMIQVETRQG CCEEECCHHHHHHHHCCCC >Mature Secondary Structure MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKGIITRIEPSLEACFVDY CCCCCCCCCCCCCEEEEEECCCCEEECCHHHHCCHHHCCCHHHHHHHHHCCCHHHEEEEC GTDRHGFLPFKEVSRSYFQDYEGGRARIQDVLKEGMEVIVQVEKDERGNKGAALTTFISL CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHH AGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAELDIPNGMSIIARTAGIGRSAEELEW HCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHH DLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRDYFRPDIGEILVDNQEVYDQVAE HHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHH FMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAFSRSVSLPSGGAIVIDHTEALVSID HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEE VNSARATRGADIEDTAFKTNMEAAEEVARQMRLRDLGGLVVIDFIDMENPKHQRDVENVL CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHH RDALKKDRARVQMGKLSRFGLLELSRQRLKPALGESSHVACPRCAGTGVIRGIESTALHV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH LRIIQEEAMKDNTGEVRAQVPVDVATFLLNEKRAELFAMEERLDVNVVLIPNIHLENPHY HHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEECCCCE EINRIRTDDVEEDGEPSYKRVAEPEEDESAKPFGGEKAKAARPEPAVKGVRHTSPAPTAA EEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCC PEKKTSWWDSFKAWLKRIFGGSETQAAPAAETSEKRSTANRSGSRANNRRQNPRRSKREG CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCC SKVEVREVAGKTARQEARADTAETRNNGNRRRNERGDRAAERANEAEIQSRNVQPAATVA CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHH DAAPSETEVQTGKRRRNGSRNERGQTAPETAAVAETAVQTAENTPSEPHTAEDKGSKPKS CCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH ERNRRERDSRDAKERRERNNQRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVHSAAAHVF HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHH GETDANAPITVSIADPVAERDLPTASPAVSNGDAPVYDAAEKIRRATAAILPEGATPKAE CCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH AQEMPSETATFTAAAEQARETAQTGGLVLIETDPAALKAWAAQPEVQTGRGLRRSEQPKP HHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCCCHHCCCCCCCCCCCC SEVATVPAEEMIQVETRQG CCEEECCHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905232; 9278503; 1447789; 1704367; 2011493; 8415644 [H]