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The map label for this gene is speE [H]

Identifier: 161870824

GI number: 161870824

Start: 1955502

End: 1956986

Strand: Reverse

Name: speE [H]

Synonym: NMCC_1906

Alternate gene names: 161870824

Gene position: 1956986-1955502 (Counterclockwise)

Preceding gene: 161870825

Following gene: 161870823

Centisome position: 90.88

GC content: 48.82

Gene sequence:

>1485_bases
GTGAACACTAAACCGAATACTAGTTTGATTTATATGCTTTCTTTCCTTAGCGGCTTATTGAGCTTGGGTATAGAAGTCTT
GTGGGTAAGGATGTTTTCGTTCGCAGCACAGTCCGTGCCTCAGGCATTTTCATTTACCCTTGCCTGTTTTCTGACCGGTA
TCGCCGTCGGCGCGTATTTTGGCAAACGGATTTGCCGCAGCCGCTTTGTTGATATTCCCTTTATCGGGCAGTGCTTCTTG
TGGGCGGGTATTGCCGACTTTTTGATTTTGGGTGCTGCGTGGTTGTTGACGGGTTTTTCCGGCTTCGTCCACCACGCCGG
TATCTTCATTACCCTGTCTGCCGTCGTCAGAGGGTTGATTTTCCCGCTCGTACACCATGTGGGTACGGATGGCAACAAAT
CCGGACGACAGGTTTCCAATGTTTATTTCTCCAACGTTGCCGGCAGTGCATTGGGTCCGGTCCTTATCGGCTTTGTGATA
CTTGATTTCTTGTCCACCCAACAGATTTACCTGCTCATCTGTTTGATTTCTGCTGCTGTCCCTTTGTTTTGTACACTGTT
CCAAAAAAGTCTCCGACTGAATGCAGTGTCGGTAGCAGTTTCCCTAATGTTCGGCATCCTCATGTTCCTACTGCCGGATT
CTGTCTTTCAAAATATTGCTGACCGTCCGGATAGGCTGATTGAAAACAAACACGGCATTGTTGCGGTTTACCATAGAGAT
GGTGATAAGGTTGTTTATGGGGCGAATGTATACGACGGCGCATACAATACCGATGTATTCAATAGTGTCAACGGCATCGA
ACGTGCCTATCTGCTACCCTCCCTGAAGTCTGGCATACGCCGCATTTTCGTCGTTGGATTGAGTACAGGTTCGTGGGCGC
GCGTCTTGTCTGCCATTCCGGAAATGCAGTCGATGATCGTTGCGGAAATCAATCCGGCATACCGTAGCCTTATCGCGGAT
GAGCCGCAAATCGCCCCGCTTTTGCAGGACAAACGTGTTGAAATTGTATTGGATGACGGTAGGAAATGGCTGCGTCGCCA
TCCTGATGAAAAATTCGACCTGATTTTGATGAATACGACTTGGTACTGGCGTGCCTATTCCACCAACCTGTTGAGTGCGG
AATTTTTAAAACAGGTGCAAAGCCACCTTACCCCGGATGGTATTGTAATGTTTAATACCACGCACAGCCCGCATGCTTTT
GCTACCGCCGTACACAGTATTCCCTATGCATACCGCTATGGGCATATGGTAGTCGGCTCGGCAACCCCGGTAGTTTTCCC
TAATAAAGAACTGCTCAAGCAACGTCTCTCCCGGTTGATTTGGCCGGAAAGCGGCAGGCACGTATTTGACAGCAGCACCG
TGGATGCTGCAGCACAAAAGGTTGTCTCTCGTATGCTGATTCAGATGACGGAACCTTCGGCTGGGGCGGAAGTCATTACC
GACGATAATATGATTGTAGAATACAAATACGGCAGAGGGATTTAA

Upstream 100 bases:

>100_bases
TACGTCTTTTTTACCCTCTCCCAAACCATTGCGCTGACAGCCTGCTTTAACCTTCTGATTGCTGCTTCAGTATGGCTGCG
TTACAGAAAGGATGGATATA

Downstream 100 bases:

>100_bases
CCGTCTTAAAGGGTTTCAGGCAACGCAGGTTTTAGGTAACGTCCTGCTAGTTCAAAAAAACCGCATCACAGCAGTCGGGA
CAAAATGGTTTAAACATTTT

Product: putative integral membrane protein

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MNTKPNTSLIYMLSFLSGLLSLGIEVLWVRMFSFAAQSVPQAFSFTLACFLTGIAVGAYFGKRICRSRFVDIPFIGQCFL
WAGIADFLILGAAWLLTGFSGFVHHAGIFITLSAVVRGLIFPLVHHVGTDGNKSGRQVSNVYFSNVAGSALGPVLIGFVI
LDFLSTQQIYLLICLISAAVPLFCTLFQKSLRLNAVSVAVSLMFGILMFLLPDSVFQNIADRPDRLIENKHGIVAVYHRD
GDKVVYGANVYDGAYNTDVFNSVNGIERAYLLPSLKSGIRRIFVVGLSTGSWARVLSAIPEMQSMIVAEINPAYRSLIAD
EPQIAPLLQDKRVEIVLDDGRKWLRRHPDEKFDLILMNTTWYWRAYSTNLLSAEFLKQVQSHLTPDGIVMFNTTHSPHAF
ATAVHSIPYAYRYGHMVVGSATPVVFPNKELLKQRLSRLIWPESGRHVFDSSTVDAAAQKVVSRMLIQMTEPSAGAEVIT
DDNMIVEYKYGRGI

Sequences:

>Translated_494_residues
MNTKPNTSLIYMLSFLSGLLSLGIEVLWVRMFSFAAQSVPQAFSFTLACFLTGIAVGAYFGKRICRSRFVDIPFIGQCFL
WAGIADFLILGAAWLLTGFSGFVHHAGIFITLSAVVRGLIFPLVHHVGTDGNKSGRQVSNVYFSNVAGSALGPVLIGFVI
LDFLSTQQIYLLICLISAAVPLFCTLFQKSLRLNAVSVAVSLMFGILMFLLPDSVFQNIADRPDRLIENKHGIVAVYHRD
GDKVVYGANVYDGAYNTDVFNSVNGIERAYLLPSLKSGIRRIFVVGLSTGSWARVLSAIPEMQSMIVAEINPAYRSLIAD
EPQIAPLLQDKRVEIVLDDGRKWLRRHPDEKFDLILMNTTWYWRAYSTNLLSAEFLKQVQSHLTPDGIVMFNTTHSPHAF
ATAVHSIPYAYRYGHMVVGSATPVVFPNKELLKQRLSRLIWPESGRHVFDSSTVDAAAQKVVSRMLIQMTEPSAGAEVIT
DDNMIVEYKYGRGI
>Mature_494_residues
MNTKPNTSLIYMLSFLSGLLSLGIEVLWVRMFSFAAQSVPQAFSFTLACFLTGIAVGAYFGKRICRSRFVDIPFIGQCFL
WAGIADFLILGAAWLLTGFSGFVHHAGIFITLSAVVRGLIFPLVHHVGTDGNKSGRQVSNVYFSNVAGSALGPVLIGFVI
LDFLSTQQIYLLICLISAAVPLFCTLFQKSLRLNAVSVAVSLMFGILMFLLPDSVFQNIADRPDRLIENKHGIVAVYHRD
GDKVVYGANVYDGAYNTDVFNSVNGIERAYLLPSLKSGIRRIFVVGLSTGSWARVLSAIPEMQSMIVAEINPAYRSLIAD
EPQIAPLLQDKRVEIVLDDGRKWLRRHPDEKFDLILMNTTWYWRAYSTNLLSAEFLKQVQSHLTPDGIVMFNTTHSPHAF
ATAVHSIPYAYRYGHMVVGSATPVVFPNKELLKQRLSRLIWPESGRHVFDSSTVDAAAQKVVSRMLIQMTEPSAGAEVIT
DDNMIVEYKYGRGI

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 54791; Mature: 54791

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEEEEEECCCCC
>Mature Secondary Structure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CCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]