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The map label for this gene is nuoH [H]

Identifier: 161870815

GI number: 161870815

Start: 1945133

End: 1946209

Strand: Reverse

Name: nuoH [H]

Synonym: NMCC_1897

Alternate gene names: 161870815

Gene position: 1946209-1945133 (Counterclockwise)

Preceding gene: 161870816

Following gene: 161870814

Centisome position: 90.38

GC content: 51.9

Gene sequence:

>1077_bases
ATGCAAGAATGGTTCCAAAACCTCTTTGCCGCAACGCTCGGTCTGGGCGATTTGGGTATTACTGTAGGCTTGGTGGTATC
CGTCATCGTCAAAATTGTGATTATCCTGATTCCGCTGATTCTGACCGTCGCCTACCTGACTTATTTTGAACGTAAAGTCA
TCGGCTTCATGCAGCTTCGCGTCGGTCCGAACGTAACCGGTCCGTGGGGTCTGATTCAGCCGTTTGCCGACGTGTTCAAA
CTCTTGTTTAAAGAAGTAACCCGTCCGAGGCTGTCAAACAAAGCCCTGTTCTACATTGGTCCGATTATGTCGCTCGCCCC
GTCTTTTGCGGCGTGGGCGGTGATTCCGTTTAACGAAGAATGGGTGCTGACCAACATCAATATCGGTCTTTTGTACATCC
TGATGATTACCTCGCTGTCGGTTTACGGCGTGATCATCGCGGGCTGGGCTTCCAACTCCAAATATTCGTTTTTGGGCGCA
ATGCGTGCTTCCGCACAAAGCATTTCCTACGAGATTGCCATGAGTGCCGCGCTGGTGTGTGTCGTGATGGTATCGGGCAG
CATGAACTTCTCCGACATCGTTGCCGCACAAGCCAAAGGTATTGCCGGCGGTTCGGTATTCTCTTGGAACTGGCTGCCGC
TCTTCCCCATCTTTATCGTCTATCTGATTTCCGCCGTTGCCGAAACCAACCGTGCGCCGTTTGACGTGGCAGAGGGTGAG
TCTGAAATCGTTGCCGGACACCACGTCGAATACTCCGGCTTCGCATTCGCACTGTTCTTCCTTGCTGAATACATTTTCAT
GATTCTGATTTCCGCGCTGACATCGTTGATGTTCCTCGGTGGTTGGTTGTCTCCGTTCCCACAAAGCTGGGGCTTTATCG
GCACGCCTTCCGCATTCTGGATGTTCGTGAAAATGGCGGCGGTTCTGTACTGGTATCTGTGGATCCGTGCAACCTTCCCG
CGCTACCGTTACGACCAAATCATGCGTTTGGGCTGGAAAGTGCTGATTCCGATCGGCTTCGCCTACATCGTGGTTTTGGG
CGTGTGGATGATTTCACCGCTGAATTTGTGGAAATAA

Upstream 100 bases:

>100_bases
ATGCCGGTTTGCCTGAAAACGTGGTGCATTTGCCGCTGCATACCGAAAATGCCGCGCTGGGTGCGTTGATGGACACTATT
GAACTGGCGGGAGCTTGATC

Downstream 100 bases:

>100_bases
GTTTCAGACGGCATCTTGAGGCCGTCTGAACAAAGCGATTTTGAATACCTAACGAAATCCCTGTTTTGAGGGAACATAAT
ATGGCTAACTTAGTAAAAAC

Product: NADH dehydrogenase I chain H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFK
LLFKEVTRPRLSNKALFYIGPIMSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGA
MRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGE
SEIVAGHHVEYSGFAFALFFLAEYIFMILISALTSLMFLGGWLSPFPQSWGFIGTPSAFWMFVKMAAVLYWYLWIRATFP
RYRYDQIMRLGWKVLIPIGFAYIVVLGVWMISPLNLWK

Sequences:

>Translated_358_residues
MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFK
LLFKEVTRPRLSNKALFYIGPIMSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGA
MRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGE
SEIVAGHHVEYSGFAFALFFLAEYIFMILISALTSLMFLGGWLSPFPQSWGFIGTPSAFWMFVKMAAVLYWYLWIRATFP
RYRYDQIMRLGWKVLIPIGFAYIVVLGVWMISPLNLWK
>Mature_358_residues
MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFK
LLFKEVTRPRLSNKALFYIGPIMSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGA
MRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGE
SEIVAGHHVEYSGFAFALFFLAEYIFMILISALTSLMFLGGWLSPFPQSWGFIGTPSAFWMFVKMAAVLYWYLWIRATFP
RYRYDQIMRLGWKVLIPIGFAYIVVLGVWMISPLNLWK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=305, Percent_Identity=40.9836065573771, Blast_Score=236, Evalue=3e-62,
Organism=Escherichia coli, GI1788618, Length=321, Percent_Identity=40.4984423676012, Blast_Score=254, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39958; Mature: 39958

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VGPNVTGPWGLIQPFADVFKLLFKEVTRPRLSNKALFYIGPIMSLAPSFAAWAVIPFNEE
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCHHHEEEEECCCC
WVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGAMRASAQSISYEIAMSAALVC
EEEEECCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGE
HHHHCCCCCHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SEIVAGHHVEYSGFAFALFFLAEYIFMILISALTSLMFLGGWLSPFPQSWGFIGTPSAFW
CCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
MFVKMAAVLYWYLWIRATFPRYRYDQIMRLGWKVLIPIGFAYIVVLGVWMISPLNLWK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVAYLTYFERKVIGFMQLR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
VGPNVTGPWGLIQPFADVFKLLFKEVTRPRLSNKALFYIGPIMSLAPSFAAWAVIPFNEE
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHCCCHHHEEEEECCCC
WVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGAMRASAQSISYEIAMSAALVC
EEEEECCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIFIVYLISAVAETNRAPFDVAEGE
HHHHCCCCCHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SEIVAGHHVEYSGFAFALFFLAEYIFMILISALTSLMFLGGWLSPFPQSWGFIGTPSAFW
CCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
MFVKMAAVLYWYLWIRATFPRYRYDQIMRLGWKVLIPIGFAYIVVLGVWMISPLNLWK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA