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The map label for this gene is coaE [H]

Identifier: 161870739

GI number: 161870739

Start: 1858822

End: 1859454

Strand: Direct

Name: coaE [H]

Synonym: NMCC_1812

Alternate gene names: 161870739

Gene position: 1858822-1859454 (Clockwise)

Preceding gene: 161870738

Following gene: 161870740

Centisome position: 86.32

GC content: 55.45

Gene sequence:

>633_bases
ATGACGGTATGGGTCGGACTGACCGGCGGAATCGGCAGCGGCAAATCGGCAGCCGCGCAATGTTTTGCCGATTTGGGCGT
ACCGCGTATCGATGCGGATGCGGCGGCGCACTCGCTGACGGCTTCAGACGGCATCGCCCTGCCGGAAATCAGGCGGCTGT
TCGGCGACACCGTTTTCGACACACAGGGTTTGTTGCGGCGCGACATATTGCGTAAAGAAATCTTTGCCTCCCCATCGCGA
AAAGCCTTGCTCGAATCCGTGATGTTGCCGCTGATTTTCTCAGAAATCAAAAAACAGCAAGAAACCTTTACCGATGCGGC
TTACGGCATTGTCGAAATTCCGCTGCTGACGGAAAAGCGTCAATTTATCAGCCTGATACGGCGTGTCCTGACCATAAGCG
CACCTTTGGAAAAACGTATCGGCAGGGTGATGGCCCGCAGCGGGCTGACGCGCGGCGAGGTGGCTGCCGTCATCAGCCAT
CAGGCATCCGAATCCGAACGCCTGCTGCTTGCAGACGATGTACTGCTCAATGACGGCAGCCTCAAAAGCCTACGTGAGAA
AACAATGCGCCTGCACGCGTTTTATTCAGGGATTTTCGCCTCAAAACCAACACAAGGAAAACACAATGGCTGA

Upstream 100 bases:

>100_bases
TTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTTTACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCT
GACCCATCCGGTGCTGTAAG

Downstream 100 bases:

>100_bases
ATCGCGGCAAACACGCCTTCAAGTCAAATGTCCGACCTGTCAAACGGCAGTAGTATGGAAACCGGAAAACGCATTCCGCC
CCTTCTGTTCGCAACGCTGC

Product: dephospho-CoA kinase (dephosphocoenzyme A kinase)

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFDTQGLLRRDILRKEIFASPSR
KALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKRQFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVAAVISH
QASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHNG

Sequences:

>Translated_210_residues
MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFDTQGLLRRDILRKEIFASPSR
KALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKRQFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVAAVISH
QASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHNG
>Mature_209_residues
TVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFDTQGLLRRDILRKEIFASPSRK
ALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKRQFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVAAVISHQ
ASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHNG

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=32.2916666666667, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=32.2916666666667, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1786292, Length=195, Percent_Identity=38.4615384615385, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=32.6424870466321, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644728, Length=190, Percent_Identity=26.8421052631579, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22875; Mature: 22744

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFD
CEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
TQGLLRRDILRKEIFASPSRKALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
QFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVAAVISHQASESERLLLADDVLLNDGS
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCEEECCCC
LKSLREKTMRLHAFYSGIFASKPTQGKHNG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFD
EEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
TQGLLRRDILRKEIFASPSRKALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
QFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVAAVISHQASESERLLLADDVLLNDGS
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCEEECCCC
LKSLREKTMRLHAFYSGIFASKPTQGKHNG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA