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The map label for this gene is pgi [H]

Identifier: 161870736

GI number: 161870736

Start: 1854452

End: 1856086

Strand: Reverse

Name: pgi [H]

Synonym: NMCC_1809

Alternate gene names: 161870736

Gene position: 1856086-1854452 (Counterclockwise)

Preceding gene: 161870741

Following gene: 161870735

Centisome position: 86.19

GC content: 59.82

Gene sequence:

>1635_bases
ATGTCCTTTTGCGCGACCGCTTTGCCTGCGAACCCGACCGTTTTGAGCGTATGCATGAGCGTTTGGACGGGATGTTGTTC
GATTACAGCAAAAACCGTTTGGGCGAAGATACGCTGCAACTGCTCTGCCGTCTTGCGGAGACGGCGGATTTGGAAGGGAA
AATGCGTGCTTTTCTGCCGTCTTGCGGAGACGGCGGATTTGGAAGGGAAAATGCGTGCTTTGCGGACGGGTGCGAAAGTC
AACGGCAGCGAGGGGCGTGCCGCGCTGCATACGGCTTTGCGCCTACCCGACGGTGCGGATGCCGTTTATGCGGACGGCAG
GGACGTGTTGCCCGAAATCCGCCGCGAGTTAAATCGTGCGTTGGAGTTTGCACACAGTTTGGACGACGGTTCGTATCAGG
GGATAACTGGGAAACGGATTACGGATTTTGTCCACATCGGCATAGGCGGATCCGACCTCGGGCCGGCAATGTGCGTGCAG
GCACTCGAGCCGTTCAGACGGCATATCGCCGTCCATTTTGCCGCCAACGCCGATCCTGCCTGCCTGGATGCGGTTTTATG
CCGTCTGAACCCCGAAACGACAGTGTTTTGCGTTGCCAGCAAGTCCTTCAAAACACCAGAAACCCTGCTCAATGCACAGG
CGGTCAAGGCGTGGTATCGCGGTGCGGGGTTCTCGGAATCCGAAACGGCGCGCCATTTTTGCGCGGTGTCTGCCGATACG
GAAGCGGCGCAAAGTTTCGGCATTGCGGCGGAACGCGTGTTTGCGATGTACGACTGGGTGGGCGGACGCTATTCCGTCTG
GTCGCCCGTCGGTTTGCCCGTGATGGTTGCGGTCGGCGGGGCGCGTTTCCGCGAGTTGTTGGCGGGGGCGCACGCGATGG
ACAGCCATTTTTTTCACACGCCGCTGCGCCGCAACATTCCCGTGCTGATGGCACTGATTGCCGTGTGGTATAACAATTTC
CAGCACGCGGATGGGCAGACTGCCGTTCCGTACAGCCACAACCTGCGCCTGCTGCCGGCGTGGCTGAACCAGCTCGATAT
GGAGAGTTTGGGCAAAAGCCGCGCTTCAGACGGCAGTCCCGCCGTGTGCAAAACGGGCGGCATCGTGTTCGGCGGTGAAG
GGGTCAACTGCCAGCACGCCTATTTCCAACTGCTTCATCAAGGCACGCGCCTGATTCCCTGCGACTTTATCGTCCCGATG
ACGGCGCAGGGCGTGGAGGACGGACGCAGCCGTTTTACCGTTGCCAACGCCTTTGCCCAAGCGGAAGCCCTGATGAAGGG
CAAAACCTTGGACGAAGCACGCGCCGAACTGGCAGATTTGCCCGAAGCGGAACGCGAACGCCTCGCGCCGCACAAAGAAT
TCCCCGGCAACCGCCCCAGCAACAGCATCCTGCTCGACCGCCTCACGCCCTACAATCTGGGTATGCTGATGGCGGCTTAC
GAACACAAAACCTTCGTCCAAGGCGCGATATGGAACGTCAACCCCTTCGATCAGTGGGGGGTTGAGTACGGCAAACAGTT
GGCGAAAACCATCATCGGCGAACTGGAAGGCGGCACGTCCGTACACGATGCCTCGACCGAAGGGCTGATGGCGTTTTACC
GCGAATGCCGTCTGAAAGGCGGCGGCGCGGCATAA

Upstream 100 bases:

>100_bases
CTGCTACATTTTAATCCGGTTCTGAAAAATCAAGGAAAACAGATGAATGCTTTTACCCGTGCATGGTATGCGCTCGAACG
CCATTATCAGGATACGCGTC

Downstream 100 bases:

>100_bases
AAGTGCCGCCGCCGTTCTGTATTGATTCGGGCACGGAAAAGGCAATACCTGCCGCCCGCCCGATTCCGAAACGCCAATGT
TCGGCAACCGCCCGTGTATT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI 2; Phosphoglucose isomerase 2; PGI 2; Phosphohexose isomerase 2; PHI 2 [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSFCATALPANPTVLSVCMSVWTGCCSITAKTVWAKIRCNCSAVLRRRRIWKGKCVLFCRLAETADLEGKMRALRTGAKV
NGSEGRAALHTALRLPDGADAVYADGRDVLPEIRRELNRALEFAHSLDDGSYQGITGKRITDFVHIGIGGSDLGPAMCVQ
ALEPFRRHIAVHFAANADPACLDAVLCRLNPETTVFCVASKSFKTPETLLNAQAVKAWYRGAGFSESETARHFCAVSADT
EAAQSFGIAAERVFAMYDWVGGRYSVWSPVGLPVMVAVGGARFRELLAGAHAMDSHFFHTPLRRNIPVLMALIAVWYNNF
QHADGQTAVPYSHNLRLLPAWLNQLDMESLGKSRASDGSPAVCKTGGIVFGGEGVNCQHAYFQLLHQGTRLIPCDFIVPM
TAQGVEDGRSRFTVANAFAQAEALMKGKTLDEARAELADLPEAERERLAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAY
EHKTFVQGAIWNVNPFDQWGVEYGKQLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKGGGAA

Sequences:

>Translated_544_residues
MSFCATALPANPTVLSVCMSVWTGCCSITAKTVWAKIRCNCSAVLRRRRIWKGKCVLFCRLAETADLEGKMRALRTGAKV
NGSEGRAALHTALRLPDGADAVYADGRDVLPEIRRELNRALEFAHSLDDGSYQGITGKRITDFVHIGIGGSDLGPAMCVQ
ALEPFRRHIAVHFAANADPACLDAVLCRLNPETTVFCVASKSFKTPETLLNAQAVKAWYRGAGFSESETARHFCAVSADT
EAAQSFGIAAERVFAMYDWVGGRYSVWSPVGLPVMVAVGGARFRELLAGAHAMDSHFFHTPLRRNIPVLMALIAVWYNNF
QHADGQTAVPYSHNLRLLPAWLNQLDMESLGKSRASDGSPAVCKTGGIVFGGEGVNCQHAYFQLLHQGTRLIPCDFIVPM
TAQGVEDGRSRFTVANAFAQAEALMKGKTLDEARAELADLPEAERERLAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAY
EHKTFVQGAIWNVNPFDQWGVEYGKQLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKGGGAA
>Mature_543_residues
SFCATALPANPTVLSVCMSVWTGCCSITAKTVWAKIRCNCSAVLRRRRIWKGKCVLFCRLAETADLEGKMRALRTGAKVN
GSEGRAALHTALRLPDGADAVYADGRDVLPEIRRELNRALEFAHSLDDGSYQGITGKRITDFVHIGIGGSDLGPAMCVQA
LEPFRRHIAVHFAANADPACLDAVLCRLNPETTVFCVASKSFKTPETLLNAQAVKAWYRGAGFSESETARHFCAVSADTE
AAQSFGIAAERVFAMYDWVGGRYSVWSPVGLPVMVAVGGARFRELLAGAHAMDSHFFHTPLRRNIPVLMALIAVWYNNFQ
HADGQTAVPYSHNLRLLPAWLNQLDMESLGKSRASDGSPAVCKTGGIVFGGEGVNCQHAYFQLLHQGTRLIPCDFIVPMT
AQGVEDGRSRFTVANAFAQAEALMKGKTLDEARAELADLPEAERERLAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAYE
HKTFVQGAIWNVNPFDQWGVEYGKQLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKGGGAA

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=489, Percent_Identity=46.0122699386503, Blast_Score=446, Evalue=1e-125,
Organism=Homo sapiens, GI296080693, Length=489, Percent_Identity=42.7402862985685, Blast_Score=396, Evalue=1e-110,
Organism=Escherichia coli, GI1790457, Length=495, Percent_Identity=44.040404040404, Blast_Score=447, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI71996708, Length=496, Percent_Identity=44.5564516129032, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI71996703, Length=496, Percent_Identity=44.5564516129032, Blast_Score=425, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6319673, Length=506, Percent_Identity=43.4782608695652, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24651916, Length=494, Percent_Identity=47.165991902834, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24651914, Length=494, Percent_Identity=47.165991902834, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17737445, Length=494, Percent_Identity=47.165991902834, Blast_Score=456, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59259; Mature: 59128

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFCATALPANPTVLSVCMSVWTGCCSITAKTVWAKIRCNCSAVLRRRRIWKGKCVLFCR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEE
LAETADLEGKMRALRTGAKVNGSEGRAALHTALRLPDGADAVYADGRDVLPEIRRELNRA
ECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHH
LEFAHSLDDGSYQGITGKRITDFVHIGIGGSDLGPAMCVQALEPFRRHIAVHFAANADPA
HHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHH
CLDAVLCRLNPETTVFCVASKSFKTPETLLNAQAVKAWYRGAGFSESETARHFCAVSADT
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCCH
EAAQSFGIAAERVFAMYDWVGGRYSVWSPVGLPVMVAVGGARFRELLAGAHAMDSHFFHT
HHHHHHCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECHHHHHHHHHHHHHHHCHHHCC
PLRRNIPVLMALIAVWYNNFQHADGQTAVPYSHNLRLLPAWLNQLDMESLGKSRASDGSP
CHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHCHHHHCCCCCCCCCC
AVCKTGGIVFGGEGVNCQHAYFQLLHQGTRLIPCDFIVPMTAQGVEDGRSRFTVANAFAQ
CEEECCCEEECCCCCCHHHHHHHHHHCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHHH
AEALMKGKTLDEARAELADLPEAERERLAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAY
HHHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHH
EHKTFVQGAIWNVNPFDQWGVEYGKQLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKG
HHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
GGAA
CCCC
>Mature Secondary Structure 
SFCATALPANPTVLSVCMSVWTGCCSITAKTVWAKIRCNCSAVLRRRRIWKGKCVLFCR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEE
LAETADLEGKMRALRTGAKVNGSEGRAALHTALRLPDGADAVYADGRDVLPEIRRELNRA
ECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHH
LEFAHSLDDGSYQGITGKRITDFVHIGIGGSDLGPAMCVQALEPFRRHIAVHFAANADPA
HHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEECCCCHH
CLDAVLCRLNPETTVFCVASKSFKTPETLLNAQAVKAWYRGAGFSESETARHFCAVSADT
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCCH
EAAQSFGIAAERVFAMYDWVGGRYSVWSPVGLPVMVAVGGARFRELLAGAHAMDSHFFHT
HHHHHHCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECHHHHHHHHHHHHHHHCHHHCC
PLRRNIPVLMALIAVWYNNFQHADGQTAVPYSHNLRLLPAWLNQLDMESLGKSRASDGSP
CHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHCHHHHCCCCCCCCCC
AVCKTGGIVFGGEGVNCQHAYFQLLHQGTRLIPCDFIVPMTAQGVEDGRSRFTVANAFAQ
CEEECCCEEECCCCCCHHHHHHHHHHCCCCEECCCEECCCCCCCCHHHHHHHHHHHHHHH
AEALMKGKTLDEARAELADLPEAERERLAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAY
HHHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHH
EHKTFVQGAIWNVNPFDQWGVEYGKQLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKG
HHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
GGAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA