Click here to switch to the map view.

The map label for this gene is pitB [C]

Identifier: 161870692

GI number: 161870692

Start: 1816366

End: 1817940

Strand: Reverse

Name: pitB [C]

Synonym: NMCC_1764

Alternate gene names: 161870692

Gene position: 1817940-1816366 (Counterclockwise)

Preceding gene: 161870706

Following gene: 161870689

Centisome position: 84.42

GC content: 52.7

Gene sequence:

>1575_bases
ATGGCTCAAATCCAAATGAGCGCAAATGTTAAAACCATCAACGCCGTCTTTGCCGCCATGCTGGTAGGTACAGTCGGCTA
TTTTATTTATGGGGGCTTGGGTTATACCCATTACAATTACGCCGCCTTATTCATTATTGCCACGATGTTCGGCGTGTTTA
TGGCGTTCAACATCGGCGGCAACGATGTTGCCAATTCTTTCGGCACCAGCGTCGGTGCGGGTACGCTGACCATCCCGCAG
GCTTTGCTGATTGCGGCGGTATTTGAGGTCAGCGGCGCGGTCATCGCGGGCGGCGAGGTAACCAATACCATACGCAAAGG
CATCGTCGATTTGAAGGGTGTTGATTTCGAACCCATACAGTTTGTGTTTATTATGATGTCCGCGCTTTTGGCGGCGGCGT
TGTGGCTGTTGTTTGCCTCGAAAAAAGGGCTTCCGGTATCTACCACCCATTCCATTATCGGCGGCATTGTCGGTAGCGCG
GTATGTATGGCGGTAATGAACGATGCCGCATCGGGCGATTTGATACGTTGGGGCAAGCTGGGCGGTATTGGTGTTTCTTG
GGTATTGTCGCCCGTGTTGGGCGGCGCGGTGTCCTATTTCCTGTTTTCGCGCGTCAAGAAAAACGTCTTAGATTACAACG
CTTGGGCGGAAGGCACGCTCAAGGGCATCAAGCAGGAAAAAAAGGCCTATAAAGAACGGCACCGCCTGTTTTTCGAGGGT
TTGTCCGAAGCCGAAAAAGTCGAGTACGCCACCAAAATGGCGCACGACGCGCAAATTTACGACGAACCCGAATTCGATCC
GCAAGAGCTGCAATCGGAGTATTACCGCGGTCTTTATGCGTTCGACAACCGTAAAAACAATGTCGATTCCTACAAGGCAC
TGCATTCTTGGATTCCCTTTATCGCTTCGTTCGGCGCGATGATGATTTCCGCTATGCTGATTTTCAAGGGCTTGAAAAAC
CTGCATTTGGGGATGAGCAACGTCAACAGCTTCCTGACCATCTTTATGATAGGCGCGGCGGTGTGGATGGGGACGTTTGT
GTTTGCCAAAAGCCTCAAGCGTAAAGACTTGGGCAAATCGACCTTTCAGATGTTTTCATGGATGCAGGTCTTTACCGCCT
GCGGTTTCGCATTCAGCCACGGTGCGAACGATATCGCCAACGCCATCGGTCCGTTTGCCGCGATTATGGATGTTTTGCGT
ACCAACAGCGTTGCCGCGCAAAATGTCGTCCCCCCGATTGCGATGCTGACTTTCGGTATCGCGCTGATTGTCGGTTTGTG
GTTTGTCGGTAAAGAGGTGATTAAAACCGTCGGTACGAGTTTGGCGGAAATGCATCCTGCTTCGGGTTTTACCGCCGAAC
TGTCCGCCGCATCCGTCGTGATGGGCGCGTCGCTGATGGGGCTGCCCGTGTCCAGTACGCATATCTTGGTCGGCGCGGTA
CTCGGCATCGGTCTGGTCAACCGCAATGCCAACTGGAAACTGATGAAGCCCATCGGTTTGGCGTGGGTCATTACCCTGCC
TGCCGCCGCCGTATTGTCGGTTGTCTGCTACTTGGTTTTACAGGCAGTATTCTGA

Upstream 100 bases:

>100_bases
AAGGATGCGTCTGCCATATCCCGAAACGGCAGTTCGACCGGAGGCAGCAGTACAGTGTCGGCAACACTCATGATTTCCAC
CACATTAAAGGAAGATTGCC

Downstream 100 bases:

>100_bases
TTGTAAAATACTGATGCCGTCTGAACCCGTGTTCAGACGGCATTTTGTTGATGGAATGTGCGGGCTTGTGCCTTATGCGC
AATCTGTTCTGTCGGGATAT

Product: inorganic phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MAQIQMSANVKTINAVFAAMLVGTVGYFIYGGLGYTHYNYAALFIIATMFGVFMAFNIGGNDVANSFGTSVGAGTLTIPQ
ALLIAAVFEVSGAVIAGGEVTNTIRKGIVDLKGVDFEPIQFVFIMMSALLAAALWLLFASKKGLPVSTTHSIIGGIVGSA
VCMAVMNDAASGDLIRWGKLGGIGVSWVLSPVLGGAVSYFLFSRVKKNVLDYNAWAEGTLKGIKQEKKAYKERHRLFFEG
LSEAEKVEYATKMAHDAQIYDEPEFDPQELQSEYYRGLYAFDNRKNNVDSYKALHSWIPFIASFGAMMISAMLIFKGLKN
LHLGMSNVNSFLTIFMIGAAVWMGTFVFAKSLKRKDLGKSTFQMFSWMQVFTACGFAFSHGANDIANAIGPFAAIMDVLR
TNSVAAQNVVPPIAMLTFGIALIVGLWFVGKEVIKTVGTSLAEMHPASGFTAELSAASVVMGASLMGLPVSSTHILVGAV
LGIGLVNRNANWKLMKPIGLAWVITLPAAAVLSVVCYLVLQAVF

Sequences:

>Translated_524_residues
MAQIQMSANVKTINAVFAAMLVGTVGYFIYGGLGYTHYNYAALFIIATMFGVFMAFNIGGNDVANSFGTSVGAGTLTIPQ
ALLIAAVFEVSGAVIAGGEVTNTIRKGIVDLKGVDFEPIQFVFIMMSALLAAALWLLFASKKGLPVSTTHSIIGGIVGSA
VCMAVMNDAASGDLIRWGKLGGIGVSWVLSPVLGGAVSYFLFSRVKKNVLDYNAWAEGTLKGIKQEKKAYKERHRLFFEG
LSEAEKVEYATKMAHDAQIYDEPEFDPQELQSEYYRGLYAFDNRKNNVDSYKALHSWIPFIASFGAMMISAMLIFKGLKN
LHLGMSNVNSFLTIFMIGAAVWMGTFVFAKSLKRKDLGKSTFQMFSWMQVFTACGFAFSHGANDIANAIGPFAAIMDVLR
TNSVAAQNVVPPIAMLTFGIALIVGLWFVGKEVIKTVGTSLAEMHPASGFTAELSAASVVMGASLMGLPVSSTHILVGAV
LGIGLVNRNANWKLMKPIGLAWVITLPAAAVLSVVCYLVLQAVF
>Mature_523_residues
AQIQMSANVKTINAVFAAMLVGTVGYFIYGGLGYTHYNYAALFIIATMFGVFMAFNIGGNDVANSFGTSVGAGTLTIPQA
LLIAAVFEVSGAVIAGGEVTNTIRKGIVDLKGVDFEPIQFVFIMMSALLAAALWLLFASKKGLPVSTTHSIIGGIVGSAV
CMAVMNDAASGDLIRWGKLGGIGVSWVLSPVLGGAVSYFLFSRVKKNVLDYNAWAEGTLKGIKQEKKAYKERHRLFFEGL
SEAEKVEYATKMAHDAQIYDEPEFDPQELQSEYYRGLYAFDNRKNNVDSYKALHSWIPFIASFGAMMISAMLIFKGLKNL
HLGMSNVNSFLTIFMIGAAVWMGTFVFAKSLKRKDLGKSTFQMFSWMQVFTACGFAFSHGANDIANAIGPFAAIMDVLRT
NSVAAQNVVPPIAMLTFGIALIVGLWFVGKEVIKTVGTSLAEMHPASGFTAELSAASVVMGASLMGLPVSSTHILVGAVL
GIGLVNRNANWKLMKPIGLAWVITLPAAAVLSVVCYLVLQAVF

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=165, Percent_Identity=38.1818181818182, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI5803173, Length=167, Percent_Identity=38.3233532934132, Blast_Score=122, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71981576, Length=477, Percent_Identity=33.7526205450734, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17536725, Length=516, Percent_Identity=26.7441860465116, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI25146401, Length=171, Percent_Identity=43.859649122807, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32566716, Length=164, Percent_Identity=44.5121951219512, Blast_Score=128, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17539280, Length=169, Percent_Identity=39.6449704142012, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17557328, Length=221, Percent_Identity=27.1493212669683, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319773, Length=153, Percent_Identity=35.2941176470588, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356511, Length=171, Percent_Identity=43.2748538011696, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 56215; Mature: 56083

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AQIQMSANVKTINAVFAAMLVGTVGYFIYGGLGYTHYNYAALFIIATMFGVFMAFNIGG
CEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC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HHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]