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The map label for this gene is anr [H]

Identifier: 161870689

GI number: 161870689

Start: 1813655

End: 1814509

Strand: Reverse

Name: anr [H]

Synonym: NMCC_1761

Alternate gene names: 161870689

Gene position: 1814509-1813655 (Counterclockwise)

Preceding gene: 161870692

Following gene: 161870687

Centisome position: 84.26

GC content: 50.64

Gene sequence:

>855_bases
GTGTCAATAAGCACATATAGTGGATTAAATTTAAATAAGGACAAGGCGAGGCAACGCCGTACTGGTTTAAATTTAATCCA
CTATAATCATGATGGGGCAAAGCGCACAAAAAGGTACGGTATGGCTTCGCATAATACTACACATCAGATGAAAACGCTGT
GTTCTTCCTGTTCTTTGCGGGAACTCTGCCTGCCTGTCGGGCTGCTGCCCAACGAGCTCAGCCAACTCGATGCCGTCATC
CGTCAAAGCCGCCGCCTGAAAAAGGGCGAATACCTGTTCTGTGTCGGCGAAGCCTTTACCTCGCTCTTTGCCATCCGTTC
GGGCTTCTTCAAAACAACCGTCGCCAGTCAGGACGGCCGCGATCAGGTAACGGGTTTCTTTATGTCGGGCGAACTCATCG
GCATGGACGGCATCTGTTCCCATGTGCACAGTTGCGACGCGGTCGCCTTGGAAGACAGCGAAGTGTGCGAACTGCCGTTT
ACCCACATCGAAGAACTGGGGCAGAATATCCCCAGCCTGCGTACCCACTTTTTCCGCATGATGAGTCGTGAAATCGTGCG
CGACCAAGGTGTTATGCTGCTGTTGGGCAATATGCGCGCCGAAGAGCGGATTGCCGCCTTTCTGTTGAACCTTTCCCAAC
GCCTTTATTCCCGAGGTTTTGCTGCCAACGACTTCATCTTAAGAATGTCCCGCGAAGAAATCGGCAGTTATCTCGGGCTG
AAACTTGAAACCGTCAGCCGCACATTATCTAAATTTCATCAGGAAGGATTGATTTCCGTCGAACACAAACACATCAAGAT
CCTCAATCTGCAGGTGTTGAAGAAGATGGTATCCGGTTGTTCGCACGCCATTTGA

Upstream 100 bases:

>100_bases
TATCTGAATGATTTTCATGGTGTGTGTGCGGTTTTATGATGTTAGTCAAATTTTGGATAGTTTGGTAGAATGCCACAGTA
TGATAAACCTGTCTTGATAT

Downstream 100 bases:

>100_bases
TTAACCCGTACGAACATTTCAGACGGCATTCTCAATAAACACAGGGCAGACGAAAACATCTGTCCTGTTTGTTGTATCTG
CCGCAAAGTGCCGTCTGAAA

Product: Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSISTYSGLNLNKDKARQRRTGLNLIHYNHDGAKRTKRYGMASHNTTHQMKTLCSSCSLRELCLPVGLLPNELSQLDAVI
RQSRRLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPF
THIEELGQNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGL
KLETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSGCSHAI

Sequences:

>Translated_284_residues
MSISTYSGLNLNKDKARQRRTGLNLIHYNHDGAKRTKRYGMASHNTTHQMKTLCSSCSLRELCLPVGLLPNELSQLDAVI
RQSRRLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPF
THIEELGQNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGL
KLETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSGCSHAI
>Mature_283_residues
SISTYSGLNLNKDKARQRRTGLNLIHYNHDGAKRTKRYGMASHNTTHQMKTLCSSCSLRELCLPVGLLPNELSQLDAVIR
QSRRLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPFT
HIEELGQNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGLK
LETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSGCSHAI

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=224, Percent_Identity=44.1964285714286, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 32034; Mature: 31902

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISTYSGLNLNKDKARQRRTGLNLIHYNHDGAKRTKRYGMASHNTTHQMKTLCSSCSLR
CCCCCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHH
ELCLPVGLLPNELSQLDAVIRQSRRLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGR
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCHHHHHHCCCCCC
DQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPFTHIEELGQNIPSLRTHFFRM
HHHHEEEECCCEECHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
MSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGL
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECHHHHHHHHCC
KLETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSGCSHAI
HHHHHHHHHHHHHHCCCEEECCCCEEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SISTYSGLNLNKDKARQRRTGLNLIHYNHDGAKRTKRYGMASHNTTHQMKTLCSSCSLR
CCCCCCCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHCCCHH
ELCLPVGLLPNELSQLDAVIRQSRRLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGR
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCHHHHHHCCCCCC
DQVTGFFMSGELIGMDGICSHVHSCDAVALEDSEVCELPFTHIEELGQNIPSLRTHFFRM
HHHHEEEECCCEECHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHH
MSREIVRDQGVMLLLGNMRAEERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGL
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECHHHHHHHHCC
KLETVSRTLSKFHQEGLISVEHKHIKILNLQVLKKMVSGCSHAI
HHHHHHHHHHHHHHCCCEEECCCCEEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]