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The map label for this gene is natD [H]

Identifier: 161870585

GI number: 161870585

Start: 1686269

End: 1687696

Strand: Reverse

Name: natD [H]

Synonym: NMCC_1651

Alternate gene names: 161870585

Gene position: 1687696-1686269 (Counterclockwise)

Preceding gene: 161870595

Following gene: 161870584

Centisome position: 78.37

GC content: 55.67

Gene sequence:

>1428_bases
ATGTTTTTCTCCGCCCTGAAATCCTTTCTTTCCCGCTACATTACCGTATGGCGCAATGTTTGGGCGGTGCGCGACCAGTT
GGAACCGCCCAAACGCACGGCGGAAGAACAGGCGTTTTTGCCCGCGCATTTGGAACTGACCGATACGCCGGTCTCTGCCG
CTCCGAAATGGGCGGCGCGTTTTATTATGGCGTTTGCGCTTTTGGCTTTGTTGTGGTCCTGGTTCGGCAAAATCGATATT
GTGGCGGCGGCTTCGGGCAAAACGGTGTCGGGCGGGCGCAGCAAAACCATCCAGCCGCTGGAAACGGTGGTGGTTAAGGC
GGTACATGTGCGCGACGGGCAGCATGTGAAACAGGGAGAAACGCTGGCGGAACTGGAGGCTGTGGGAACAGACAGCGATG
TGGTGCAGTCGGAGCAGGCTTTGCAGGCTGCCCAATTGTCCAAACTGCGTTATGAAGCGGTATTGGCGGCATTGGAAAGC
CGTACCGTGCCGCATATCGATATGGCGCAAGCACGGTCTTTAGGTCTCTCCGATGCCGATGTGCAATCGGCGCAGGTGTT
GGCGCAGCACCAGTATCAGGCATGGGCGGCGCAGGATGCGCAATTGCAGTCGGCTTTGCGCGGCCATCAGGCGGAATTGC
AGTCGGCCAAGGCGCAGGAGCAGAAGCTGGTTTCGGTGGGGGCGATCGAGCAGCAGAAAACAGCAGACTACCGCCGTTTG
CGGGCCGACAATTTTATTTCGGAACATGCGTTTTTGGAGCAGCAGAGCAAATCGGTCAGCAATTGGAACGATTTGGAAAG
TACGCGCGGTCAGATGAGGCAGATTCAGGCGGCCATTGCACAGGCGGAGCAGAATCGGGTGCTGAATACGCAGAACCTGA
AACGCGATACGCTGGATGCGCTGCGCCAGGCAAACGAACAGATTGACCAATACCGCGGCCAAATGGATAAGGCAAAGCAG
CGGCAGCAGCTGATGACAATACAGTCGCCTGCGGACGGCACGGTGCAGGAATTGGCCACCTATACGGTGGGCGGTGTGGT
GCAGGCTGCCCAAAAAATGATGGTGGTTGCGCCCGATGACGACAAAATGGACGTGGAAGTTTTGGTATTGAACAAAGACA
TCGGTTTTGTGGAACAGGGACAGGATGCGGTGGTGAAGATTGAGAGTTTTCCCTATACGCGCTACGGTTATCTGACGGGC
AAGGTGAAAAGTGTCAGCCATGATGCGGTAAGCCACGAACAGTTGGGCTTGGTTTATACGGCGGTGGTGTCGCTGGACAA
ACATACCTTGAATATTGACGGCAAAGCAGTGAATCTGACGGCGGGCATGAATGTCACGGCGGAGATTAAAACGGGTAAAC
GGCGGGTGCTGGATTATCTGTTAAGCCCGCTGCAAACCAAATTGGACGAAAGCTTTAGGGAGCGATAG

Upstream 100 bases:

>100_bases
TATTCCCGCCTTTCCCTTAACAGCTGCCGCGCTTTCCGTTAAAATTCCTTTACATATTTATATTGTTTCCTGTTTCTATA
TTGCCAAGGTTATACCCGTT

Downstream 100 bases:

>100_bases
GCGGATCCATACTGGGCATTTGTTATCCGCCGGTTCGGACATGCAGACTGCCTGAAACCATTGCCCGGATGACATTGCTC
AATCTAATGATAATGCAAGA

Product: periplasmic type I secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MFFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQAFLPAHLELTDTPVSAAPKWAARFIMAFALLALLWSWFGKIDI
VAAASGKTVSGGRSKTIQPLETVVVKAVHVRDGQHVKQGETLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALES
RTVPHIDMAQARSLGLSDADVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRRL
RADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLDALRQANEQIDQYRGQMDKAKQ
RQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVVAPDDDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTG
KVKSVSHDAVSHEQLGLVYTAVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER

Sequences:

>Translated_475_residues
MFFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQAFLPAHLELTDTPVSAAPKWAARFIMAFALLALLWSWFGKIDI
VAAASGKTVSGGRSKTIQPLETVVVKAVHVRDGQHVKQGETLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALES
RTVPHIDMAQARSLGLSDADVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRRL
RADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLDALRQANEQIDQYRGQMDKAKQ
RQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVVAPDDDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTG
KVKSVSHDAVSHEQLGLVYTAVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER
>Mature_475_residues
MFFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQAFLPAHLELTDTPVSAAPKWAARFIMAFALLALLWSWFGKIDI
VAAASGKTVSGGRSKTIQPLETVVVKAVHVRDGQHVKQGETLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALES
RTVPHIDMAQARSLGLSDADVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRRL
RADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLDALRQANEQIDQYRGQMDKAKQ
RQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVVAPDDDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTG
KVKSVSHDAVSHEQLGLVYTAVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER

Specific function: Involved in the transport of the hemolysin/leukotoxin [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 52696; Mature: 52696

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQAFLPAHLELTDTPVSAAPKWAAR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHCCCCCEEEEECCCCCCCHHHHHH
FIMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLETVVVKAVHVRDGQHVKQGE
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALESRTVPHIDMAQARSLGLSDAD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCH
VQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLDA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHH
LRQANEQIDQYRGQMDKAKQRQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVVAPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCC
DKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTGKVKSVSHDAVSHEQLGLVYT
CCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEECCHHHCCHHHHHHHHHHHHHH
AVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER
HHHHHCCEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFSALKSFLSRYITVWRNVWAVRDQLEPPKRTAEEQAFLPAHLELTDTPVSAAPKWAAR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCHHHHCCCCCEEEEECCCCCCCHHHHHH
FIMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLETVVVKAVHVRDGQHVKQGE
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
TLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALESRTVPHIDMAQARSLGLSDAD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCH
VQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKAQEQKLVSVGAIEQQKTADYRRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQAAIAQAEQNRVLNTQNLKRDTLDA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHH
LRQANEQIDQYRGQMDKAKQRQQLMTIQSPADGTVQELATYTVGGVVQAAQKMMVVAPDD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCC
DKMDVEVLVLNKDIGFVEQGQDAVVKIESFPYTRYGYLTGKVKSVSHDAVSHEQLGLVYT
CCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEECCHHHCCHHHHHHHHHHHHHH
AVVSLDKHTLNIDGKAVNLTAGMNVTAEIKTGKRRVLDYLLSPLQTKLDESFRER
HHHHHCCEEEECCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2402458; 1961107 [H]