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The map label for this gene is clpB [H]

Identifier: 161870340

GI number: 161870340

Start: 1403540

End: 1406119

Strand: Direct

Name: clpB [H]

Synonym: NMCC_1384

Alternate gene names: 161870340

Gene position: 1403540-1406119 (Clockwise)

Preceding gene: 161870336

Following gene: 161870343

Centisome position: 65.18

GC content: 52.48

Gene sequence:

>2580_bases
ATGCGATACGACAAATTAACCGCCAAATTCCAACAGGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACGGCAG
CTATCTGGAAGCGGGCTTTGTGCTGAAAGCCCTGCTTGACGACCAAAACAGCGGTGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTGAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGCCAGGGCGGCGAC
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCCGCAACCAAACGCGGCGATGCCTATATCGC
CAGTGAACTTTTCCTGCTTGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATTTTGAAAGAAGCCGGCGCGACCGAAC
AAAACATCAATGCCGCGATTGACACGGTACGAGGAGGACAAAACGTGAACGATGCCAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATATACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGCCGTGACGACGAAAT
CCGCCGTGCGATTCAGGTATTGCAACGCCGTACCAAAAACAACCCTGTGCTGATTGGCGAACCGGGCGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCACAACGCATCGTCAACGGCGAAGTACCCGAATCCCTGCGCAACAAACGCCTACTGGTTTTG
GACTTGGCGGCATTGATTGCCGGCGCGAAATACCGCGGCGAATTTGAAGAACGCTTGAAAGGCGTGTTGAACGACTTGGC
GAAAGACGACGGCAACACTCTGATTTTCATCGACGAAATCCATACTTTGGTCGGCGCAGGCAAAACCGACGGTGCGATGG
ATGCGGGCAATATGCTGAAACCGGCTTTGGCACGTGGCGAATTGCACTGTATCGGCGCGACCACCTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGCTTCCAAAAAGTATTGGTCGGCGAGCCAAGTGTAGAAGACACCAT
CGCTATCTTGCGCGGTTTACAGGAGCGTTATGAAATCCACCACGGTATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTCCTGCCTGATAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAGCCGGAAGCAATGGACAAAATCGACCGCCGTCTAATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCAACGGTCTGCAAAAAG
AATACGCCGATTTAGACGAAATCTGGAAAGCCGAAAAAGCAATTTCAGACGGTGCTGCTAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCAGAGGAAATCGCAGAAGTGGTTTCCCGTATGACCGGCATTCCTGTGTCAAAAATGATGGAAGGCGAACGC
GACAAGTTGCTGAAAATGGAAGAAGTGTTGCACCGCCGCGTAGTCGGTCAAGACGAAGCCGTGCGTGCCGTGTCCGACGC
CATCCGCCGCAGCCGCTCCGGTCTTGCCGACCCGAATAAACCTTACGGCAGCTTCCTGTTCTTGGGCCCGACCGGCGTGG
GTAAAACCGAGTTGTGCAAAGCATTGGCAGGCTTCCTGTTTGACAGTGAAGATCATCTGATTCGTATCGATATGTCCGAA
TATATGGAAAAACACGCCGTTGCCCGCCTCATCGGCGCGCCTCCAGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGAC
CGAACAAGTCCGCCGCAAACCGTACAGCGTAATTCTTTTGGACGAAGTGGAAAAAGCCCATCCCGATGTGTTCAACATCC
TGCTGCAAGTATTGGATGACGGCCGCTTGACCGACGGACAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGTACTCAAGACTACGAAGCGGTGAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCTGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCACGGACTGGATCAGGCAAACA
TCCGCAGTATTGCCAAAATCCAGCTTAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTCCGCCTGACTGTTTCCGAT
GCCGCTCTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCCATCCAGTCGGA
AATCGAAAACCCGCTGGCAAAAGCTCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAGGGTAGAAGCCAACGGCG
ACAGACTGAAATTTGCCTGA

Upstream 100 bases:

>100_bases
ATATCGAATTAAATATAGAAAAACAGAAAACAGAACTTGAGTTATCCACAATTATGCACATATAGGCTTCGACAGCGGAC
ATTTTGAAAAGGAAACAAAA

Downstream 100 bases:

>100_bases
TTCGTTCCTGCTGTTGAAAATGCCGTCTGAAACGGGAATCTCCGTTTCAGACGGCATTTTTTATCCTCGGCAGACAAACC
GTCCCCTTATTGGCGGTAGG

Product: ATP-dependent Clp protease ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDTVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEANGDRLKFA

Sequences:

>Translated_859_residues
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDTVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEANGDRLKFA
>Mature_859_residues
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDTVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEANGDRLKFA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=303, Percent_Identity=37.2937293729373, Blast_Score=206, Evalue=7e-53,
Organism=Escherichia coli, GI1788943, Length=857, Percent_Identity=66.5110851808635, Blast_Score=1167, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=391, Percent_Identity=40.4092071611253, Blast_Score=271, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=52.8089887640449, Blast_Score=745, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=852, Percent_Identity=44.7183098591549, Blast_Score=683, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95112; Mature: 95112

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQV
CCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHH
KQRLQQHLNSLPKVSGQGGDILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQND
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
AAGKILKEAGATEQNINAAIDTVRGGQNVNDANAEDQRDALKKYTLDLTQRARDGKLDPV
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGELHCIGATTLDEYRQYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIH
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASRVKMEKETKPEAMDKIDRRLI
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHH
AEVVSRMTGIPVSKMMEGERDKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNK
HHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
PYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSEYMEKHAVARLIGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCC
EEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
CCCCCHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKI
ECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
QLKGLEKRLEKQNLRLTVSDAALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGN
HHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
YAPESEIRVEANGDRLKFA
CCCCCCEEEEECCCEECCC
>Mature Secondary Structure
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQV
CCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHH
KQRLQQHLNSLPKVSGQGGDILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQND
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
AAGKILKEAGATEQNINAAIDTVRGGQNVNDANAEDQRDALKKYTLDLTQRARDGKLDPV
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGELHCIGATTLDEYRQYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIH
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASRVKMEKETKPEAMDKIDRRLI
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHH
AEVVSRMTGIPVSKMMEGERDKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNK
HHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
PYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSEYMEKHAVARLIGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCC
EEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
CCCCCHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNIGSQHIQQMGTQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKI
ECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHH
QLKGLEKRLEKQNLRLTVSDAALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGN
HHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
YAPESEIRVEANGDRLKFA
CCCCCCEEEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]