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The map label for this gene is aroD [H]

Identifier: 161870315

GI number: 161870315

Start: 1372442

End: 1373239

Strand: Direct

Name: aroD [H]

Synonym: NMCC_1357

Alternate gene names: 161870315

Gene position: 1372442-1373239 (Clockwise)

Preceding gene: 161870313

Following gene: 161870316

Centisome position: 63.73

GC content: 57.39

Gene sequence:

>798_bases
ATGGCGGCTGTTTTTTCTGTGTGTGCCTGTTTTATGTGTTCCTGCCTTGTTGTCAAAAATACCGTTATCGGAAGCGGACG
CACCAAAATCGCCGTGCCGCTTGTCGCCCGCGATGCCGCCGAACTTTCCGCCGTACTTGAGCAAATCAAAAATATGCCCT
TCGATATTGCGGAGTTCCGCGCCGACTTTTTGGAATGCGCGGGCAGTATCGGCGAAATATTGCACCACACGCAGACCGTC
CGCGACGCGCTGCCCGACAAGCCGCTGCTGTTTACGTTCAGACGGCATGGCGAAGGCGGCTCGTTCCCGTGTTCGGACGA
TTATTATTTTAAACTGCTCGACGCGCTGATCGAAAGTCGCCTGCCCGACATTATCGATATCGAGCTGTTTTCCGGCGAAA
CCGCCGTCCGGCGCGCTGTGGCGAATGCTCAAAAAAACGGCATCGCCGCCCTGCTCTGCAATCATGAGTTTCACCGCACG
CCGCCGCAAGAAGAAATCGTATGCCGTCTGAAACAGATGGAGGACTGCGGCGCGGACATCTGCAAAATTGCGGTGATGCC
GCAAAGCGCGGAAGATGTGCTGACTTTGCTTTCCGCCACGCTCAAAGCGAAAGAGCTTGCCGCCAAACCGATTGTTACGA
TGTCGATGGGGCAGACGGGGGCGGTCAGCCGGCTTGCCGGACAGGTGTTCGGCTCAAGCATCACGTTCGGTTCGGGAACG
CAAAACTCCGCGCCGGGGCAAATCGGCGTATCCGCCCTCCGTGCGACACTCGACTGCCTCGAAAACGGCGCAGACTGA

Upstream 100 bases:

>100_bases
TTATCGCATATTTCCTTGCTTGCCGATATGCGCCAGGACGCGGCGGCTTGTGCCGGAATGGAATCTGGATGCCGTCTAAA
AGGCGGCCGGCTTTGTTATA

Downstream 100 bases:

>100_bases
TTTCAGACAGCATCAAAACATGATGAAACTCAATCCCCAACAGCTCGAAGCCGTCCGCTACCTCGGCGGCCCACTGCTCG
TCCTTGCCGGTGCAGGCAGC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAAVFSVCACFMCSCLVVKNTVIGSGRTKIAVPLVARDAAELSAVLEQIKNMPFDIAEFRADFLECAGSIGEILHHTQTV
RDALPDKPLLFTFRRHGEGGSFPCSDDYYFKLLDALIESRLPDIIDIELFSGETAVRRAVANAQKNGIAALLCNHEFHRT
PPQEEIVCRLKQMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQVFGSSITFGSGT
QNSAPGQIGVSALRATLDCLENGAD

Sequences:

>Translated_265_residues
MAAVFSVCACFMCSCLVVKNTVIGSGRTKIAVPLVARDAAELSAVLEQIKNMPFDIAEFRADFLECAGSIGEILHHTQTV
RDALPDKPLLFTFRRHGEGGSFPCSDDYYFKLLDALIESRLPDIIDIELFSGETAVRRAVANAQKNGIAALLCNHEFHRT
PPQEEIVCRLKQMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQVFGSSITFGSGT
QNSAPGQIGVSALRATLDCLENGAD
>Mature_264_residues
AAVFSVCACFMCSCLVVKNTVIGSGRTKIAVPLVARDAAELSAVLEQIKNMPFDIAEFRADFLECAGSIGEILHHTQTVR
DALPDKPLLFTFRRHGEGGSFPCSDDYYFKLLDALIESRLPDIIDIELFSGETAVRRAVANAQKNGIAALLCNHEFHRTP
PQEEIVCRLKQMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQVFGSSITFGSGTQ
NSAPGQIGVSALRATLDCLENGAD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=252, Percent_Identity=45.2380952380952, Blast_Score=226, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 28369; Mature: 28238

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVFSVCACFMCSCLVVKNTVIGSGRTKIAVPLVARDAAELSAVLEQIKNMPFDIAEFR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ADFLECAGSIGEILHHTQTVRDALPDKPLLFTFRRHGEGGSFPCSDDYYFKLLDALIESR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHC
LPDIIDIELFSGETAVRRAVANAQKNGIAALLCNHEFHRTPPQEEIVCRLKQMEDCGADI
CCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCHHH
CKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQVFGSSITFGSGT
HEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCC
QNSAPGQIGVSALRATLDCLENGAD
CCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAVFSVCACFMCSCLVVKNTVIGSGRTKIAVPLVARDAAELSAVLEQIKNMPFDIAEFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ADFLECAGSIGEILHHTQTVRDALPDKPLLFTFRRHGEGGSFPCSDDYYFKLLDALIESR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHC
LPDIIDIELFSGETAVRRAVANAQKNGIAALLCNHEFHRTPPQEEIVCRLKQMEDCGADI
CCCEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCHHH
CKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQVFGSSITFGSGT
HEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCC
QNSAPGQIGVSALRATLDCLENGAD
CCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA