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The map label for this gene is fis [C]

Identifier: 161870285

GI number: 161870285

Start: 1333446

End: 1333685

Strand: Reverse

Name: fis [C]

Synonym: NMCC_1326

Alternate gene names: 161870285

Gene position: 1333685-1333446 (Counterclockwise)

Preceding gene: 161870286

Following gene: 161870284

Centisome position: 61.93

GC content: 47.08

Gene sequence:

>240_bases
ATGCCCCATACCCTTCCCGATATTTCCCAATGTATCAGACAAAATTTGGAACAATATTTCAAAGACCTGAACGGTACCGA
ACCTTGCGGCGTGTACGATATGGTATTGCATCAGGTGGAAAAACCGCTGCTGGTGTGCGTGATGGAACAATGCGGCGGCA
ACCAGTCCAAAGCCTCCGTCATGTTGGGACTGAACCGCAATACCTTGCGTAAAAAACTGATTCAACACGGTTTATTGTGA

Upstream 100 bases:

>100_bases
CAGGTTATCTTGAAAGACTTGCCGGAAAAACCGACCGTTGGGCGTGCGCCTACCGCCCAAATGCCTTCTGAACACTTGAT
TATCCTTTGAAAGTGCAATC

Downstream 100 bases:

>100_bases
ATATGGCTGCAAGCGTCCGTATTTTGGGCATCGACCCGGGCAGCCGCGTAACGGGTTTCGGTGTCATCGATGTCAGGGGG
CGCGATCATTTTTACGTCGC

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 79; Mature: 78

Protein sequence:

>79_residues
MPHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLLVCVMEQCGGNQSKASVMLGLNRNTLRKKLIQHGLL

Sequences:

>Translated_79_residues
MPHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLLVCVMEQCGGNQSKASVMLGLNRNTLRKKLIQHGLL
>Mature_78_residues
PHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLLVCVMEQCGGNQSKASVMLGLNRNTLRKKLIQHGLL

Specific function: Activates Ribosomal RNA Transcription. Plays A Direct Role In Upstream Activation Of rRNA Promoters. Binds To A Recombinational Enhancer Sequence That Is Required To Stimulate Hin-Mediated DNA Inversion. Prevents Initiation Of DNA Replication From Oric.

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family

Homologues:

Organism=Escherichia coli, GI1789661, Length=71, Percent_Identity=45.0704225352113, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FISL_NEIMA (P64130)

Other databases:

- EMBL:   AL157959
- RefSeq:   YP_002342936.1
- ProteinModelPortal:   P64130
- SMR:   P64130
- EnsemblBacteria:   EBNEIT00000000203
- GeneID:   908021
- GenomeReviews:   AL157959_GR
- KEGG:   nma:NMA1632
- GeneTree:   EBGT00050000020647
- HOGENOM:   HBG509520
- OMA:   QSEASRI
- ProtClustDB:   PRK01905
- BioCyc:   NMEN122587:NMA1632-MONOMER
- HAMAP:   MF_00166
- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- PIRSF:   PIRSF002097
- PRINTS:   PR01590

Pfam domain/function: PF02954 HTH_8; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 8938; Mature: 8806

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLLVCVMEQCGGNQSKASV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
MLGLNRNTLRKKLIQHGLL
HHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLLVCVMEQCGGNQSKASV
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
MLGLNRNTLRKKLIQHGLL
HHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919