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The map label for this gene is ruvC [H]

Identifier: 161870284

GI number: 161870284

Start: 1332907

End: 1333449

Strand: Reverse

Name: ruvC [H]

Synonym: NMCC_1325

Alternate gene names: 161870284

Gene position: 1333449-1332907 (Counterclockwise)

Preceding gene: 161870285

Following gene: 161870283

Centisome position: 61.92

GC content: 61.69

Gene sequence:

>543_bases
GTGAATATGGCTGCAAGCGTCCGTATTTTGGGCATCGACCCGGGCAGCCGCGTAACGGGTTTCGGTGTCATCGATGTCAG
GGGGCGCGATCATTTTTACGTCGCCTCCGGCTGCATCAAAACGCCTGCCGATGCGCCTCTGGCAGACAGGATTGCCGTGA
TTGTGCGGCACATCGGCGAAGTCGTTGCCGTTTACAAGCCGCAGCAGGCGGCGGTGGAACAGGTGTTCGTCAACGTCAAT
CCTGCATCGACGCTGATGCTCGGTCAGGCGCGGGGCGCGGCATTGGCGGCATTGGTCAGCCATAAGCTGCCCGTTTCGGA
ATACACGGCCTTGCAGGTCAAACAGGCGGTAGTCGGCAAAGGCAAGGCGGCAAAAGAACAGGTGCAGCATATGGTGGTGC
AGATGCTGGGGCTTTCGGGAACGCCGCAGGCGGATGCGGCGGACGGTCTTGCCGTCGCGCTGACCCACGCCTTACGCAAC
CACGGGCTTGCGTCCCGGCTCAACCCGTCGGGGATGCAGGTCAAGCGCGGAAGGTTTCAATAG

Upstream 100 bases:

>100_bases
GCGTGATGGAACAATGCGGCGGCAACCAGTCCAAAGCCTCCGTCATGTTGGGACTGAACCGCAATACCTTGCGTAAAAAA
CTGATTCAACACGGTTTATT

Downstream 100 bases:

>100_bases
TTTCAGACGGCATTTGTATTTTGCCGTCTGAAAAGAAAATGTGTATCGAGATGAAATTTATATTTTTTGTACTGTATGTT
TTGCAGTTTCTGCCGTTTGC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNMAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVN
PASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRN
HGLASRLNPSGMQVKRGRFQ

Sequences:

>Translated_180_residues
MNMAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVN
PASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRN
HGLASRLNPSGMQVKRGRFQ
>Mature_180_residues
MNMAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVN
PASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRN
HGLASRLNPSGMQVKRGRFQ

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=172, Percent_Identity=50.5813953488372, Blast_Score=139, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18908; Mature: 18908

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGE
CCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
VVAVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGK
HHEEECCHHHHHHHHEEECCCHHEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHGLASRLNPSGMQVKRGRFQ
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNMAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGE
CCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
VVAVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGK
HHEEECCHHHHHHHHEEECCCHHEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
GKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHGLASRLNPSGMQVKRGRFQ
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA