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The map label for this gene is pgl [H]

Identifier: 161870265

GI number: 161870265

Start: 1307686

End: 1308381

Strand: Reverse

Name: pgl [H]

Synonym: NMCC_1306

Alternate gene names: 161870265

Gene position: 1308381-1307686 (Counterclockwise)

Preceding gene: 161870266

Following gene: 161870264

Centisome position: 60.76

GC content: 53.3

Gene sequence:

>696_bases
ATGTTTGTTTGGCACGAATACGAAAATGCGGCAGAAGCGGCGCAGTCTTTGACTGACGCAGTGGCGGATGCTTTGCAGGG
CGCACTGGACGAGAAGGGCGGTGCGGTGTTGGCAGTTTCCGGCGGACGTTCGCCGATTGCATTTTTCAACGCCCTGTCGC
AAAAAGATTTGGATTGGAAAAACGTCGGCATCACCTTGGCAGATGAACGCATCGTGCCGACCGTCCACGCCGACAGCAAT
ACCGGTTTGGTGCGCGAATACCTGTTGAAGAACAAAGCGGAAGCGGCAATGTGGATTCCTATGGTGGAAGACGGAAAAAC
TGAAACCGAATTACATCCCGATGCTGTTGTCGATTATGCACTGAAACATTACAAGCAGCCCGATGTTTTGGTTTTGGGTA
TGGGAAACGACGGGCATACGGCTTCGATTTTCCCGAAAGCTCCGCAGTTTCAGACGGCAATCGACGGTTCGGCAGGTGTC
GCGCTGGTGCATACCACGCCCGTTACCGCGCCGCACGAGCGCGTCAGCATGACCTTGGATGCGATTGCCCATACGGGGCA
TGTATTTTTGGCGATACAGGGCGAAGAGAAAAAAGCCGTGTTCGAACAAGCCGCACAAGGCGAAAACCGCGAATATCCGA
TCAACCTCGTTTTGAACCATCAAGGAGTGAACTGCCATGTCTTCTACGCCGAATAA

Upstream 100 bases:

>100_bases
ATATTTGGTATCAAAAGCATAAACAACTGTTCGGCCGACATATTGCTCAACCCGTTTCCATAACGGAATATGCCGTCTGA
AATAAAAAAAGGACACAAAT

Downstream 100 bases:

>100_bases
ACAAGCCGGATATCCCCGACTGGTCGCCGATATCGGCGGGACGAATGCACGCTTTGCGCTGGAAACCGCGCCGCGCGTCA
TTGAAAAAGCCGCCGTGCTT

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MFVWHEYENAAEAAQSLTDAVADALQGALDEKGGAVLAVSGGRSPIAFFNALSQKDLDWKNVGITLADERIVPTVHADSN
TGLVREYLLKNKAEAAMWIPMVEDGKTETELHPDAVVDYALKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGV
ALVHTTPVTAPHERVSMTLDAIAHTGHVFLAIQGEEKKAVFEQAAQGENREYPINLVLNHQGVNCHVFYAE

Sequences:

>Translated_231_residues
MFVWHEYENAAEAAQSLTDAVADALQGALDEKGGAVLAVSGGRSPIAFFNALSQKDLDWKNVGITLADERIVPTVHADSN
TGLVREYLLKNKAEAAMWIPMVEDGKTETELHPDAVVDYALKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGV
ALVHTTPVTAPHERVSMTLDAIAHTGHVFLAIQGEEKKAVFEQAAQGENREYPINLVLNHQGVNCHVFYAE
>Mature_231_residues
MFVWHEYENAAEAAQSLTDAVADALQGALDEKGGAVLAVSGGRSPIAFFNALSQKDLDWKNVGITLADERIVPTVHADSN
TGLVREYLLKNKAEAAMWIPMVEDGKTETELHPDAVVDYALKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGV
ALVHTTPVTAPHERVSMTLDAIAHTGHVFLAIQGEEKKAVFEQAAQGENREYPINLVLNHQGVNCHVFYAE

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=173, Percent_Identity=33.5260115606936, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533058, Length=216, Percent_Identity=30.0925925925926, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533060, Length=219, Percent_Identity=29.6803652968037, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321957, Length=219, Percent_Identity=25.1141552511416, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24996; Mature: 24996

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVWHEYENAAEAAQSLTDAVADALQGALDEKGGAVLAVSGGRSPIAFFNALSQKDLDWK
CEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCHH
NVGITLADERIVPTVHADSNTGLVREYLLKNKAEAAMWIPMVEDGKTETELHPDAVVDYA
HCCEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
LKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGVALVHTTPVTAPHERVSMTLD
HHHCCCCCEEEEEECCCCCEEEECCCCCCCCEECCCCCCEEEEEECCCCCCHHHHHHHHH
AIAHTGHVFLAIQGEEKKAVFEQAAQGENREYPINLVLNHQGVNCHVFYAE
HHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MFVWHEYENAAEAAQSLTDAVADALQGALDEKGGAVLAVSGGRSPIAFFNALSQKDLDWK
CEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCCCCHH
NVGITLADERIVPTVHADSNTGLVREYLLKNKAEAAMWIPMVEDGKTETELHPDAVVDYA
HCCEEEECCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
LKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGVALVHTTPVTAPHERVSMTLD
HHHCCCCCEEEEEECCCCCEEEECCCCCCCCEECCCCCCEEEEEECCCCCCHHHHHHHHH
AIAHTGHVFLAIQGEEKKAVFEQAAQGENREYPINLVLNHQGVNCHVFYAE
HHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]