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The map label for this gene is clpX [H]

Identifier: 161870243

GI number: 161870243

Start: 1285275

End: 1286519

Strand: Reverse

Name: clpX [H]

Synonym: NMCC_1284

Alternate gene names: 161870243

Gene position: 1286519-1285275 (Counterclockwise)

Preceding gene: 161870249

Following gene: 161870241

Centisome position: 59.74

GC content: 52.05

Gene sequence:

>1245_bases
ATGTCCAACGAAAACCGTACCTGTTCCTTTTGCGGAAAATCCAAATCACACGTCAAACATTTAATTGAGGGCGAAAACGC
CTTTATCTGTGACGAATGCGTCTCAAACTGTATTGAAATATTGCATGAAGACGGAAATGACGGCACACCTTCGGAAAGTG
CCGGAGGGGAGCCGGAAGAATCCGGCAAGCTGCCCACGCCCGCCGAAATCGTCGCCAACCTCAACGACCACGTTATCGGT
CAGGAACAAGCCAAGAAAGCCTTGGCGGTGTCGGTGTACAACCATTACAAACGCCTGCGCCACCCGAAAGCCGGAGCTAA
TGTCGAATTGTCGAAATCCAACATCCTGCTTATCGGCCCGACCGGATCGGGTAAAACCCTGCTGGCGCAATCTTTGGCGC
GTAAACTGGATGTGCCGTTCGTGATGGCGGATGCAACCACGCTGACTGAAGCAGGTTATGTCGGCGAAGATGTCGAGCAA
ATCATCACCAAACTGTTGGGCAAATGTGATTTCGATGTTGAAAAAGCCCAGCGCGGCATCGTCTATATCGACGAAATCGA
TAAAATTTCACGCAAAGGCGACAATCCGTCCATCACGCGCGACGTGTCCGGCGAAGGTGTGCAACAAGCCTTGCTGAAAC
TGATTGAAGGTACGGTGGCAAGTGTTCCGCCCCAAGGCGGCCGCAAGCATCCGAATCAGGAATTTATCAACGTCGATACC
ACCAACATCCTGTTTATCTGCGGCGGTGCGTTTGCAGGCTTGGAAAAAGTCATCCGCCAGCGCACCGAGAAAGGCGGTAT
CGGTTTCGGTGCGTCCGTTCACAGCAAGGACGAAAATGCCGACATTACCAAGCTGTTCGGCATCGTCGAACCGGAAGATT
TAATCAAATTCGGTCTGATTCCGGAATTAATCGGACGTTTGCCCGTGATTGCAACACTAGAAGAACTGGATGAGGACGCG
CTGATTAATATTTTGACCGAGCCGAAAAATGCTTTGGTCAAGCAGTATCAAGCCTTGTTCGGTATGGAAAATGTCGAGTT
GGAATTTGAAGAAGGCGCATTGCGTTCCATCGCGCGTCAGGCAATGGAGCGCAAAACCGGCGCGCGCGGCCTGAGGTCCA
TCGTCGAACGCTGCCTGCTCGATACGATGTACCGCCTGCCTGATTTGCAAGGCTTGAAAAAAGTGGTGGTCGGTAAGGCA
GTCATCGAAGAGGGCAGGGAACCGGAATTGGTGTTCGAGTCCTGA

Upstream 100 bases:

>100_bases
TTTTAAGGTAATACATTGATAAGAACGGATATAGTTATTATACTTGGCAACCCGAACGGCACGTGCCGTTTTCTGTAACG
CATACATTGTAAAGAAAGCC

Downstream 100 bases:

>100_bases
TGGCAAACAAAACCGCTTCGGAACGTTGAACCACGTTTCCGAAGCGGTTTTTTGTTTTTGATGCCTAGGGGCGGTTTGCG
GCGGCAAATTCCGTCAGCAC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEESGKLPTPAEIVANLNDHVIG
QEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQ
IITKLLGKCDFDVEKAQRGIVYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDT
TNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDA
LINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLQGLKKVVVGKA
VIEEGREPELVFES

Sequences:

>Translated_414_residues
MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEESGKLPTPAEIVANLNDHVIG
QEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQ
IITKLLGKCDFDVEKAQRGIVYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDT
TNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDA
LINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLQGLKKVVVGKA
VIEEGREPELVFES
>Mature_413_residues
SNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEESGKLPTPAEIVANLNDHVIGQ
EQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQI
ITKLLGKCDFDVEKAQRGIVYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDTT
NILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDAL
INILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLQGLKKVVVGKAV
IEEGREPELVFES

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=327, Percent_Identity=51.6819571865443, Blast_Score=311, Evalue=8e-85,
Organism=Escherichia coli, GI1786642, Length=406, Percent_Identity=68.9655172413793, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI1790366, Length=220, Percent_Identity=35, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=329, Percent_Identity=44.0729483282675, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=329, Percent_Identity=44.0729483282675, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=415, Percent_Identity=39.5180722891566, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=275, Percent_Identity=40.3636363636364, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319704, Length=451, Percent_Identity=38.1374722838137, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24648291, Length=328, Percent_Identity=47.2560975609756, Blast_Score=294, Evalue=8e-80,
Organism=Drosophila melanogaster, GI24648289, Length=328, Percent_Identity=47.2560975609756, Blast_Score=293, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45070; Mature: 44939

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEE
CCCCCCEEHHCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
SGKLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGP
CCCCCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEC
TGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGI
CCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCE
VYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDT
EEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCEEECCC
TNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLI
CEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHH
PELIGRLPVIATLEELDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQ
HHHHCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
AMERKTGARGLRSIVERCLLDTMYRLPDLQGLKKVVVGKAVIEEGREPELVFES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
SNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEE
CCCCCEEHHCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
SGKLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGP
CCCCCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEC
TGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQIITKLLGKCDFDVEKAQRGI
CCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCCCE
VYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDT
EEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCCEEECCC
TNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLI
CEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHH
PELIGRLPVIATLEELDEDALINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQ
HHHHCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
AMERKTGARGLRSIVERCLLDTMYRLPDLQGLKKVVVGKAVIEEGREPELVFES
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA