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The map label for this gene is pdxH [H]

Identifier: 161870230

GI number: 161870230

Start: 1270982

End: 1271614

Strand: Reverse

Name: pdxH [H]

Synonym: NMCC_1271

Alternate gene names: 161870230

Gene position: 1271614-1270982 (Counterclockwise)

Preceding gene: 161870232

Following gene: 161870224

Centisome position: 59.05

GC content: 57.82

Gene sequence:

>633_bases
ATGGATTTGCACAATATTCGGGAAGATTACAGCAAACGGGAATTGTCGGAAGGCGATTGCGCCGACAATCCGATCGAGCA
GTTCGAGCGGTGGTTGGACGAGGCGGTACGCGCCGAGGTTAACGAGCCGACGGCGGTCAATGTGGCGGCGGTCGACGGAC
GCGGCAGGCCTAACAGCCGTATGGTGCTGCTGAAGGAAGTTAATTCTGAAGGTTTTGTTTTCTTTACGAATTATCACAGC
CGCAAGGGGCGTTCGCTGGATGCTCATCCGTTTGCGGCGATGACGTTTTTCTGGCCGGAGCTGGAGCGTCAGGTGCGCGT
GGAAGGGCGTGTTGAAAGGCTGGCGGAGAAGTTGTCGGACGAATATTTTGAGAGTCGCCCGTATCAGAGCCGTTTGGGTG
CGTGGGCAAGCGCGCAGAGCGAAGTGATTCCGAACAAGGCGGTATTGGTGGCAAAGGCGGCGGCGGTCGGACTCAAACAT
CCTTTGCATGTGCCGCGTCCGCCGCATTGGGGCGGCTATATTGTGATTCCCGATTTGCTTGAGTTTTGGCAGGGCAGGCC
GAGCAGGCTGCACGACCGCATCCAATACCGTTTGCTGGATGGTGGCTGGATACGCGAGCGGCTGTCGCCTTGA

Upstream 100 bases:

>100_bases
TCACTTGGTGCTTGAGCACCTTAGAGAATCGTTCTCTTTGAGCTAAGGCGAGGCAACGCCGTATTGGTTTTTGTTAATCC
ACTATTAAGAGGAGCGGTAA

Downstream 100 bases:

>100_bases
ACAGGAAAAAACATATGCCGTCTGAAAACCGGAATCGGGTTTCAGACGGCATTTTTTCACGGGGAAAATACGGACGGGAA
GTTTTTTGTGTTCCGAACGG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAEVNEPTAVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHS
RKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKH
PLHVPRPPHWGGYIVIPDLLEFWQGRPSRLHDRIQYRLLDGGWIRERLSP

Sequences:

>Translated_210_residues
MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAEVNEPTAVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHS
RKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKH
PLHVPRPPHWGGYIVIPDLLEFWQGRPSRLHDRIQYRLLDGGWIRERLSP
>Mature_210_residues
MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAEVNEPTAVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHS
RKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKH
PLHVPRPPHWGGYIVIPDLLEFWQGRPSRLHDRIQYRLLDGGWIRERLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=202, Percent_Identity=44.5544554455446, Blast_Score=173, Evalue=1e-43,
Organism=Escherichia coli, GI1787926, Length=207, Percent_Identity=41.5458937198068, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17553712, Length=221, Percent_Identity=40.2714932126697, Blast_Score=160, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=40.6698564593301, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI45551845, Length=228, Percent_Identity=41.2280701754386, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24644901, Length=228, Percent_Identity=41.2280701754386, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24644903, Length=162, Percent_Identity=31.4814814814815, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24203; Mature: 24203

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAEVNEPTAVNVAAVDGRGRPNSR
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
MVLLKEVNSEGFVFFTNYHSRKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSD
EEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKHPLHVPRPPHWGGYIVIPDLL
HHHHCCCCHHHHCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHH
EFWQGRPSRLHDRIQYRLLDGGWIRERLSP
HHHCCCHHHHHHHHHEEECCCHHHHHHCCC
>Mature Secondary Structure
MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAEVNEPTAVNVAAVDGRGRPNSR
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
MVLLKEVNSEGFVFFTNYHSRKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSD
EEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKHPLHVPRPPHWGGYIVIPDLL
HHHHCCCCHHHHCCHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHH
EFWQGRPSRLHDRIQYRLLDGGWIRERLSP
HHHCCCHHHHHHHHHEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA