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The map label for this gene is trxB [H]

Identifier: 161870199

GI number: 161870199

Start: 1228618

End: 1229442

Strand: Reverse

Name: trxB [H]

Synonym: NMCC_1239

Alternate gene names: 161870199

Gene position: 1229442-1228618 (Counterclockwise)

Preceding gene: 161870204

Following gene: 161870198

Centisome position: 57.09

GC content: 54.67

Gene sequence:

>825_bases
ATGACCACCACCGAAGTGGACAACTGGCCTGCCGATGCCGACGGCGTGCAAGGGCCGGAATTGATGGCGCGGTTTCTCGC
CCACGCCGAACGTTTCGGAACGGAAATCATTTTTGACCAAATCAACGCCGTCGATCTGCAAAAACGCCCGTTTACACTCA
AAGGCGATATGGGCGAGTACACTTGCGATGCCCTGATTGTCGCAACAGGCGCGTCCGCCAAATACCTCGGTTTGCCGAGT
GAGGAAGCGTTTGCCGGAAAAGGCGTTTCCGCTTGTGCCACCTGCGACGGTTTCTTCTACAAAAACCAAGATGTTGCCGT
AGTCGGCGGCGGCAATACGGCAGTTGAAGAGGCACTCTACCTTGCCAATATCGCCAAAACCGTTACCCTGATCCACCGCC
GCAGCGAGTTCCGTGCCGAAAAAATCATGATCGACAAACTGATGAAACGCGTGGAAGAGGGCAAAATCATCCTCAAGCTG
GAAAGCAACCTGCAAGAAGTACTGGGCGACGATCGGGGCGTAAACGGCGCATTATTAAAAAACAACGACGGTTCTGAGCA
ACAAATTGCCGTCAGCGGCATTTTTATCGCCATCGGGCACAAGCCGAATACCGATATTTTCAAAGGTCAGTTGGAAATGG
ACGAAGCCGGTTACCTGAAAACCAAAGGCGGCACGGCGGACAATGTCGGCGCAACCAATATCGAAGGCGTATGGGCGGCG
GGCGACGTAAAAGACCATACCTACCGTCAGGCGATTACCAGCGCGGCTTCCGGCTGTCAGGCGGCTTTGGACGCGGAACG
CTGGCTGGGCAGCCAAAACATTTGA

Upstream 100 bases:

>100_bases
TTTGGGTTCCGGTCCCGCCGGATACACCGCCGCCGTCTATGCCGCGCGCGCCAATTTAAACCCCGTCATTATTACAGGTA
TCGCGCAAGGCGGGCAACTG

Downstream 100 bases:

>100_bases
ATGCCGTCTGAAACCGAAATTTTCGGCGGAATGCAAGTTTTTCGCACCAAATCCTTGATTCCGTCGGCAAACCCCAATAT
AATGCCTGCTCTTTGAACCT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTTTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEYTCDALIVATGASAKYLGLPS
EEAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEALYLANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKL
ESNLQEVLGDDRGVNGALLKNNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNIEGVWAA
GDVKDHTYRQAITSAASGCQAALDAERWLGSQNI

Sequences:

>Translated_274_residues
MTTTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEYTCDALIVATGASAKYLGLPS
EEAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEALYLANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKL
ESNLQEVLGDDRGVNGALLKNNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNIEGVWAA
GDVKDHTYRQAITSAASGCQAALDAERWLGSQNI
>Mature_273_residues
TTTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEYTCDALIVATGASAKYLGLPSE
EAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEALYLANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKLE
SNLQEVLGDDRGVNGALLKNNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNIEGVWAAG
DVKDHTYRQAITSAASGCQAALDAERWLGSQNI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=270, Percent_Identity=65.5555555555556, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI87081763, Length=278, Percent_Identity=31.294964028777, Blast_Score=124, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=278, Percent_Identity=45.6834532374101, Blast_Score=227, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6321898, Length=279, Percent_Identity=43.7275985663082, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 29423; Mature: 29292

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCEEEECCCCCC
TCDALIVATGASAKYLGLPSEEAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEALY
EEEEEEEEECCCCEEECCCCCHHHCCCCCCHHEECCCEEECCCCEEEEECCCHHHHHHHH
LANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKLESNLQEVLGDDRGVNGALLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCCEEEE
NNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNIEGVWAA
CCCCCCCEEEEEEEEEEECCCCCCCCEECEEEECCCCEEEECCCCCCCCCCCCCCEEEEC
GDVKDHTYRQAITSAASGCQAALDAERWLGSQNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEY
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCEEEECCCCCC
TCDALIVATGASAKYLGLPSEEAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEALY
EEEEEEEEECCCCEEECCCCCHHHCCCCCCHHEECCCEEECCCCEEEEECCCHHHHHHHH
LANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKLESNLQEVLGDDRGVNGALLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCCEEEE
NNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNIEGVWAA
CCCCCCCEEEEEEEEEEECCCCCCCCEECEEEECCCCEEEECCCCCCCCCCCCCCEEEEC
GDVKDHTYRQAITSAASGCQAALDAERWLGSQNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]