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The map label for this gene is ykuM [H]

Identifier: 161870107

GI number: 161870107

Start: 1134483

End: 1135397

Strand: Reverse

Name: ykuM [H]

Synonym: NMCC_1146

Alternate gene names: 161870107

Gene position: 1135397-1134483 (Counterclockwise)

Preceding gene: 161870114

Following gene: 161870104

Centisome position: 52.73

GC content: 54.86

Gene sequence:

>915_bases
ATGGATGCCGTACAATTAAAATCATTTGTCGCCGTCGCGCACGAGGGCAACCTTACCCAAGCCGCCAAACGACTTTTCCT
TTCCCAGCCTGCCGTTTCCGCCCAAATTAAAGCCCTTGAAGAATATGTCGGCACGCCGCTGTTCAGGCGCACGGGGAAAG
GCATGGTATTGACGCGGGCGGGCGAAATACTGTTGCCCGAAGCGGAATCCCTGCTGCAATACAAACACAAGTTGGAGTAT
TTTGCCAAAACGCTGGCAGGCGATTATTCGGAAGAGACCAGTTTGGGCATTATCCACCCCATCGATTCGGCAAAGCTCGT
CGCGCTGACGGACAATATCGGTCAAACAGCCCCCAAAACGCGCCTGCACATCCAATACGGAATGAGCGGCGAAATCCTCT
CGCGCATCCAACACAAAACCCTGCACGGCGGCTTTATACTCGGCAACGCCGCCCAACGGGGCATCCGCAGCGTATTCCTG
CAAAACCTGACCTACGCGCTGATTTGCCCGCAAAGCCAATATCCCCATCTGACCCGCTCCCTTCCGCAGAGCCTGCAAGA
ATGCGTATGGATAGAAATGTCGGGCGTGTCCGGAAGTAGGAAGCACCTGCACCAGTTTTGGCGCAGCAACCGGCTCTCAC
CCAAAAAACAGATATTGTGCGACTACCCCCAAACCATTATCGATTTGGTTGCAGGCGGTATAGGTGTGGCAATGGTGCCG
GGAAACAAAGCCGAAGCGGCGGCAAAAGAAGGCGCGGGCGTGGCTATTATCGAATCGTGCCGCCACAGTATGCCGCTCAA
TTTCATTTATGCGGAAGAATACGAGGATAATCCCCACGTCTCACTCCTGCTCGAGTGCATTGAAAAAGTATGGGGAGTGC
AGGCGGTGCAGCCGCCCGTTGTCTCGGACAACTGA

Upstream 100 bases:

>100_bases
ATTTACAAACCACTTGATTAAAAAGTTAATTTTCAGCAACAATCCGCCTAAAAGATTTCGATTGCACAAATATAGAAAAC
ATCCGCACAAGGAGGGATAT

Downstream 100 bases:

>100_bases
AATAAATCCTGCTTTGCTGATTGTTTTAAAATAGAAATTTGAATTTTATCACGCTGAAAACACTGAAAACGCCATCCGCA
TTCTCTCAAATACGGCTTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVGTPLFRRTGKGMVLTRAGEILLPEAESLLQYKHKLEY
FAKTLAGDYSEETSLGIIHPIDSAKLVALTDNIGQTAPKTRLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFL
QNLTYALICPQSQYPHLTRSLPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQILCDYPQTIIDLVAGGIGVAMVP
GNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYEDNPHVSLLLECIEKVWGVQAVQPPVVSDN

Sequences:

>Translated_304_residues
MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVGTPLFRRTGKGMVLTRAGEILLPEAESLLQYKHKLEY
FAKTLAGDYSEETSLGIIHPIDSAKLVALTDNIGQTAPKTRLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFL
QNLTYALICPQSQYPHLTRSLPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQILCDYPQTIIDLVAGGIGVAMVP
GNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYEDNPHVSLLLECIEKVWGVQAVQPPVVSDN
>Mature_304_residues
MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVGTPLFRRTGKGMVLTRAGEILLPEAESLLQYKHKLEY
FAKTLAGDYSEETSLGIIHPIDSAKLVALTDNIGQTAPKTRLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFL
QNLTYALICPQSQYPHLTRSLPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQILCDYPQTIIDLVAGGIGVAMVP
GNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYEDNPHVSLLLECIEKVWGVQAVQPPVVSDN

Specific function: Positive Regulator Required For The Expression Of Xapa And Xapb. Binds To The Inducer Xanthosine. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=291, Percent_Identity=23.0240549828179, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=25.8064516129032, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=283, Percent_Identity=26.1484098939929, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=279, Percent_Identity=24.3727598566308, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=240, Percent_Identity=24.1666666666667, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=65, Percent_Identity=50.7692307692308, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787806, Length=247, Percent_Identity=23.4817813765182, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=98, Percent_Identity=35.7142857142857, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786713, Length=149, Percent_Identity=30.2013422818792, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789506, Length=239, Percent_Identity=25.5230125523013, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33439; Mature: 33439

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVGTPLFRRTGKGMVLTRA
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEEC
GEILLPEAESLLQYKHKLEYFAKTLAGDYSEETSLGIIHPIDSAKLVALTDNIGQTAPKT
CCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCC
RLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFLQNLTYALICPQSQYPHLTRS
EEEEEECCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
LPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQILCDYPQTIIDLVAGGIGVAMVP
HHHHHHHHEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCEEEEEC
GNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYEDNPHVSLLLECIEKVWGVQAVQPPV
CCCHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCC
VSDN
CCCC
>Mature Secondary Structure
MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVGTPLFRRTGKGMVLTRA
CCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCEEEEEC
GEILLPEAESLLQYKHKLEYFAKTLAGDYSEETSLGIIHPIDSAKLVALTDNIGQTAPKT
CCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCC
RLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFLQNLTYALICPQSQYPHLTRS
EEEEEECCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHH
LPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQILCDYPQTIIDLVAGGIGVAMVP
HHHHHHHHEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCCCEEEEEC
GNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYEDNPHVSLLLECIEKVWGVQAVQPPV
CCCHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCC
VSDN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]