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The map label for this gene is degU [H]

Identifier: 161870093

GI number: 161870093

Start: 1118122

End: 1118778

Strand: Direct

Name: degU [H]

Synonym: NMCC_1131

Alternate gene names: 161870093

Gene position: 1118122-1118778 (Clockwise)

Preceding gene: 161870092

Following gene: 161870096

Centisome position: 51.92

GC content: 54.64

Gene sequence:

>657_bases
ATGACCATTAAAATTATCCTGATAGACGACCATACCCTTTTCCGCAGCGGCATCAAGGCACTTTTGTCGCGCCAACATGA
TTTTGAGGTCATCGGCGAAGCCGCAGACGGCCTCTCGGGCATTAAAATGATCAACCGGCTGCAACCCGATGTCGTCCTGC
TTGACCTTGATATGCCCGGTATGAACGGACGCGAAGCACTCTCCCAAATCATCAGCATCAATCCGCAGCAGGCAGTGATT
ATGCTGACCGTTTCCGAAGACAACGACGACTTGACCGAATGTATGCGCATCGGCGCGCGCGGCTACCTGCTGAAAAACAT
CAACGCCGACTTTCTGCTCGAAAGCATACGCAAAGCCGCCGAAGGCGATAATGTATTCTCGCCCGAGATGACCGCCAAAC
TCGTTAAAAGCCTGATTTCCCCCCAACCTGCCCAAGGGACACAGGCACTCTCCTCTCTTACCCCTCGCGAACTGGAAATC
TTGGGCTATCTCGCCGCAGGACACAGCAACAAAATCATCGCCCGCCACCTCGATCTTGCCGAATCCACCGTCAAAGTCCA
CGTTCAAAACCTGCTCCGCAAACTCAACCTCAGCAGCCGGGTGCAGGCCGCTGTTTACGCCATCCGGCACAACGTCCCCC
AACCCGTGCTGGAATAA

Upstream 100 bases:

>100_bases
AGGAGCGTGCCAAACGTATCCGCGCCGTATTGAAAATCTATTCCCAACCCCAACAGGGAACCACCGTCTCATTGGCGGGT
GTATCTGAAGAAAGCTTGAA

Downstream 100 bases:

>100_bases
GGCGGGTTCAGACGGCATATTAGGGGTTTTAATCCCCGTACGGTCATTCGGATAACAGACCAAGCATGTAAGTTTATGCC
CCCATAAGTACGCTTGGCAT

Product: two-component system, NarL family nitrate/nitrite response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTIKIILIDDHTLFRSGIKALLSRQHDFEVIGEAADGLSGIKMINRLQPDVVLLDLDMPGMNGREALSQIISINPQQAVI
MLTVSEDNDDLTECMRIGARGYLLKNINADFLLESIRKAAEGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEI
LGYLAAGHSNKIIARHLDLAESTVKVHVQNLLRKLNLSSRVQAAVYAIRHNVPQPVLE

Sequences:

>Translated_218_residues
MTIKIILIDDHTLFRSGIKALLSRQHDFEVIGEAADGLSGIKMINRLQPDVVLLDLDMPGMNGREALSQIISINPQQAVI
MLTVSEDNDDLTECMRIGARGYLLKNINADFLLESIRKAAEGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEI
LGYLAAGHSNKIIARHLDLAESTVKVHVQNLLRKLNLSSRVQAAVYAIRHNVPQPVLE
>Mature_217_residues
TIKIILIDDHTLFRSGIKALLSRQHDFEVIGEAADGLSGIKMINRLQPDVVLLDLDMPGMNGREALSQIISINPQQAVIM
LTVSEDNDDLTECMRIGARGYLLKNINADFLLESIRKAAEGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEIL
GYLAAGHSNKIIARHLDLAESTVKVHVQNLLRKLNLSSRVQAAVYAIRHNVPQPVLE

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=214, Percent_Identity=41.588785046729, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1787473, Length=202, Percent_Identity=44.0594059405941, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=31.9047619047619, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=33.9901477832512, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788712, Length=209, Percent_Identity=30.622009569378, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786747, Length=203, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082052, Length=106, Percent_Identity=29.2452830188679, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789937, Length=203, Percent_Identity=25.615763546798, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23964; Mature: 23833

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIILIDDHTLFRSGIKALLSRQHDFEVIGEAADGLSGIKMINRLQPDVVLLDLDMPG
CEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCC
MNGREALSQIISINPQQAVIMLTVSEDNDDLTECMRIGARGYLLKNINADFLLESIRKAA
CCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHH
EGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEILGYLAAGHSNKIIARHLDLA
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
ESTVKVHVQNLLRKLNLSSRVQAAVYAIRHNVPQPVLE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TIKIILIDDHTLFRSGIKALLSRQHDFEVIGEAADGLSGIKMINRLQPDVVLLDLDMPG
EEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCC
MNGREALSQIISINPQQAVIMLTVSEDNDDLTECMRIGARGYLLKNINADFLLESIRKAA
CCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHH
EGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEILGYLAAGHSNKIIARHLDLA
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
ESTVKVHVQNLLRKLNLSSRVQAAVYAIRHNVPQPVLE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]