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The map label for this gene is narQ [H]

Identifier: 161870092

GI number: 161870092

Start: 1116515

End: 1118125

Strand: Direct

Name: narQ [H]

Synonym: NMCC_1130

Alternate gene names: 161870092

Gene position: 1116515-1118125 (Clockwise)

Preceding gene: 161870088

Following gene: 161870093

Centisome position: 51.85

GC content: 50.65

Gene sequence:

>1611_bases
TTGAGAATGCAGGCATACCGTCTGGCATACATGGCGGGTGAAGGATCTCCCCGCTCCCAAATAGACAATCAGGTTGACGA
ATTTGAAAAAAGCCTGAATCGTATTTCACAAAGTGATGCCATCCATCCGCTGATTCCTTCGGACACCCCTCTTGCTTATG
ATTTGATACAATCCATGCTGATTATAGATTGGCAGGCACACATCCTCCCCCCGCTCCAGTCCTACCGGCGACCGACTCAG
GTCGATCTCTACCGCTTTGCCGGAAACATCGAACTGTTTTTGCAGGCATTGGAAAATGCCAACGAAAAAAACACATGGTG
GCTCAGGCGTTTTCAATGGGCAATTATGTTGATGACGCTGGTGTCGTCTGTACTGATGCTGTTTTGGCACCAGATTTGGG
TTATCCGGCCGCTGCAGGCGTTAAGGGAAGGTGCGGAACGCATCGGACGGAGGTGTTTCGATATTCCGGTTCCCGAAGGC
GGTACGCCGGAATTCAAACAGGTCGGGCGTTGTTTCAATCAAATGGGCGGCAGGTTGAAAATTTTATATGATGATTTGGA
AGGACAAGTCGCCGAGCAGACACGCAGTCTCGAAAAACAAAATCAAAACCTGACCCTGCTGTACCAAACTACACGGGACC
TGCACCAATCCTACATACCGCAACAGGCTGCAGAACATTTTCTAAACCGTATCCTGCCCGCCGTAGGAGCAGATTCCGGC
AGAGTTTGTTTGGACGGCGGATCCGATGTTTATGTTTCCATTCATCATGCGGATTGCGGCACAGCAGCTTCGGATTTGGG
GAAGTACCATGAGGAAATCTTCCCCATTGAGTACCAGAACGAAACATTGGGCAGGCTGTTGCTCAGCTTTCCAAACGGCA
TTTCTCTTGATGAAGACGACCGCATCCTGCTTCAAACACTAGGCAGGCAATTGGGCGTATCGCTTGCCGGCGCAAAACAG
GAGGAAGAAAAACGCCTGCTTGCAGTATTGCAGGAACGCAACCTGATTGCGCAAGGATTACATGACAGCATCGCACAAGC
ATTAACGTTCCTAAACCTACAGGTACAGATGCTGGAAACCGCCTTTGCCGAAAACAAACGGGAGGAAGCCGCAGAAAACA
TCGGCTTCATCAAAACAGGCGTGCAGGAATGTTATGAAGATGTCCGCGAACTGCTGCTCAACTTCCGTACCAAAATCAGT
AATAAAGAATTTCCCGAAGCCGTTGCCGACCTATTCGCGCGCTTCACGCAACAGACCGGCACGACTGTCGAAACCGTTTG
GGAAAACGGCACGCACCTGCCTACACAGGACGAGCAGCTCCAAATGATTTTTATCCTGCAAGAAAGCCTGTCCAACATCC
GCAAACACGCCCGCGCCACCCATGTAAAATTCACCCTTTCCGAACACGGCGGACGCTTTACCATGACCATCCAAGACAAC
GGACAAGGTTTCGACACGGAGAAAATAGGAGAACCCACGGGCAGCCATGTCGGACTGCACATCATGCAGGAGCGTGCCAA
ACGTATCCGCGCCGTATTGAAAATCTATTCCCAACCCCAACAGGGAACCACCGTCTCATTGGCGGGTGTATCTGAAGAAA
GCTTGAAATGA

Upstream 100 bases:

>100_bases
CGGACTGTGGGTCGGGTTGGCGGCATTGTCTGTCGTTTTGACACTGCTGCTCTCTTTGCGTCTGGAAAACGCGGCCTCCG
TCATCGAAGAGGCGGGCAAC

Downstream 100 bases:

>100_bases
CCATTAAAATTATCCTGATAGACGACCATACCCTTTTCCGCAGCGGCATCAAGGCACTTTTGTCGCGCCAACATGATTTT
GAGGTCATCGGCGAAGCCGC

Product: two-component system, NarL family nitrate/nitrite sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MRMQAYRLAYMAGEGSPRSQIDNQVDEFEKSLNRISQSDAIHPLIPSDTPLAYDLIQSMLIIDWQAHILPPLQSYRRPTQ
VDLYRFAGNIELFLQALENANEKNTWWLRRFQWAIMLMTLVSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEG
GTPEFKQVGRCFNQMGGRLKILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQAAEHFLNRILPAVGADSG
RVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQNETLGRLLLSFPNGISLDEDDRILLQTLGRQLGVSLAGAKQ
EEEKRLLAVLQERNLIAQGLHDSIAQALTFLNLQVQMLETAFAENKREEAAENIGFIKTGVQECYEDVRELLLNFRTKIS
NKEFPEAVADLFARFTQQTGTTVETVWENGTHLPTQDEQLQMIFILQESLSNIRKHARATHVKFTLSEHGGRFTMTIQDN
GQGFDTEKIGEPTGSHVGLHIMQERAKRIRAVLKIYSQPQQGTTVSLAGVSEESLK

Sequences:

>Translated_536_residues
MRMQAYRLAYMAGEGSPRSQIDNQVDEFEKSLNRISQSDAIHPLIPSDTPLAYDLIQSMLIIDWQAHILPPLQSYRRPTQ
VDLYRFAGNIELFLQALENANEKNTWWLRRFQWAIMLMTLVSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEG
GTPEFKQVGRCFNQMGGRLKILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQAAEHFLNRILPAVGADSG
RVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQNETLGRLLLSFPNGISLDEDDRILLQTLGRQLGVSLAGAKQ
EEEKRLLAVLQERNLIAQGLHDSIAQALTFLNLQVQMLETAFAENKREEAAENIGFIKTGVQECYEDVRELLLNFRTKIS
NKEFPEAVADLFARFTQQTGTTVETVWENGTHLPTQDEQLQMIFILQESLSNIRKHARATHVKFTLSEHGGRFTMTIQDN
GQGFDTEKIGEPTGSHVGLHIMQERAKRIRAVLKIYSQPQQGTTVSLAGVSEESLK
>Mature_536_residues
MRMQAYRLAYMAGEGSPRSQIDNQVDEFEKSLNRISQSDAIHPLIPSDTPLAYDLIQSMLIIDWQAHILPPLQSYRRPTQ
VDLYRFAGNIELFLQALENANEKNTWWLRRFQWAIMLMTLVSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEG
GTPEFKQVGRCFNQMGGRLKILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQAAEHFLNRILPAVGADSG
RVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQNETLGRLLLSFPNGISLDEDDRILLQTLGRQLGVSLAGAKQ
EEEKRLLAVLQERNLIAQGLHDSIAQALTFLNLQVQMLETAFAENKREEAAENIGFIKTGVQECYEDVRELLLNFRTKIS
NKEFPEAVADLFARFTQQTGTTVETVWENGTHLPTQDEQLQMIFILQESLSNIRKHARATHVKFTLSEHGGRFTMTIQDN
GQGFDTEKIGEPTGSHVGLHIMQERAKRIRAVLKIYSQPQQGTTVSLAGVSEESLK

Specific function: Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the narL/narP proteins. NarQ probably activates narL and narP by phosphorylation. NarQ probably negatively regulates the narL protein by dephosphorylation [H]

COG id: COG3850

COG function: function code T; Signal transduction histidine kinase, nitrate/nitrite-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=550, Percent_Identity=29.0909090909091, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787474, Length=576, Percent_Identity=24.8263888888889, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR016380
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60893; Mature: 60893

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMQAYRLAYMAGEGSPRSQIDNQVDEFEKSLNRISQSDAIHPLIPSDTPLAYDLIQSML
CCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
IIDWQAHILPPLQSYRRPTQVDLYRFAGNIELFLQALENANEKNTWWLRRFQWAIMLMTL
HHCCHHHCCCCHHHCCCCCCEEHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEGGTPEFKQVGRCFNQMGGRLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCEEE
ILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQAAEHFLNRILPAVGADSG
EEEECCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
RVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQNETLGRLLLSFPNGISLDEDD
CEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEECCHHHHHHHHHCCCCCCCCCCC
RILLQTLGRQLGVSLAGAKQEEEKRLLAVLQERNLIAQGLHDSIAQALTFLNLQVQMLET
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAENKREEAAENIGFIKTGVQECYEDVRELLLNFRTKISNKEFPEAVADLFARFTQQTG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
TTVETVWENGTHLPTQDEQLQMIFILQESLSNIRKHARATHVKFTLSEHGGRFTMTIQDN
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEEECC
GQGFDTEKIGEPTGSHVGLHIMQERAKRIRAVLKIYSQPQQGTTVSLAGVSEESLK
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCC
>Mature Secondary Structure
MRMQAYRLAYMAGEGSPRSQIDNQVDEFEKSLNRISQSDAIHPLIPSDTPLAYDLIQSML
CCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
IIDWQAHILPPLQSYRRPTQVDLYRFAGNIELFLQALENANEKNTWWLRRFQWAIMLMTL
HHCCHHHCCCCHHHCCCCCCEEHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEGGTPEFKQVGRCFNQMGGRLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHCCEEE
ILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQAAEHFLNRILPAVGADSG
EEEECCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCC
RVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQNETLGRLLLSFPNGISLDEDD
CEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEECCHHHHHHHHHCCCCCCCCCCC
RILLQTLGRQLGVSLAGAKQEEEKRLLAVLQERNLIAQGLHDSIAQALTFLNLQVQMLET
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAENKREEAAENIGFIKTGVQECYEDVRELLLNFRTKISNKEFPEAVADLFARFTQQTG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
TTVETVWENGTHLPTQDEQLQMIFILQESLSNIRKHARATHVKFTLSEHGGRFTMTIQDN
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEEECC
GQGFDTEKIGEPTGSHVGLHIMQERAKRIRAVLKIYSQPQQGTTVSLAGVSEESLK
CCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1528845; 1508040; 9205837; 9278503 [H]