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The map label for this gene is tadA [H]

Identifier: 161869845

GI number: 161869845

Start: 878607

End: 879326

Strand: Reverse

Name: tadA [H]

Synonym: NMCC_0876

Alternate gene names: 161869845

Gene position: 879326-878607 (Counterclockwise)

Preceding gene: 161869846

Following gene: 161869844

Centisome position: 40.83

GC content: 56.25

Gene sequence:

>720_bases
ATGCTGACCACACCGCCGCTCGCCCCCAAAACCGTCGCCGCCCTGCACAGGCTCGGTATCCGTACGCTCGAAGAACTGCG
GCAAAACGGTTCGGTCAAAGCCTTTCTGCTGCTCAAAGCATCGGGTTTGACCCTCACGAAAAGCACACTGTGGCAGCTTC
AGTCGCTGCTGGACGACACGCTGCCGCAAGAAATGTCCCAAGCGCATAAAGCCCGCCTTCTTGCCGAATTGAAAAACCAT
CCGCCCGTCGCCGCCTTCCCATCGCAGGAAGAAATGGAACACTTCATGCGCGAAGCACTGCGCCAAGCAGAACAATCCGC
CGCCGACGGCGAAATACCCGTCGGGGCAGTCATTGTTTCAGACGGCAAAATCATCGCATCGGCACACAACACCTGCATTG
CCGACTGCAATGTCAGCCGACACGCCGAAATCAACGCCTTGGCACAGGCAGGCAGAGAAATACAAAACTACCGCCTTGAC
GGATGCGACATATATATCACCCTCGAACCCTGCGCCATGTGCGCGTCCGCACTGATACAGGCACGAATCAGGCGTGTGAT
ATATGGTGCGGCAGAACCCAAAACCGGCGCGGCAGGCAGCATTGTCAACCTGTTTGCCGACAAACGCCTCAATACGCACA
CCGCCATACGGGGCGGAATCCTGCAAGAAGAATGCCGCGCCGTATTAAGCCGTTTTTTTCAGAACAAAAGAAAAGGTTGA

Upstream 100 bases:

>100_bases
GCGCAAAACACCTTTAGACTGCGTTGCCGACCCGTTTTCAGACGGCACTTCATGCACACGCCTGATTGAGGCGGCAAAAC
GGTTTTTCGGCGCATAAACC

Downstream 100 bases:

>100_bases
ACCTATGACCGTACTGACCGTCATCCTCGCCCTCGCCCTGATAGCCGTCGGCACGGCGGGCATCGTTTACCCCGCCCTGC
CCGGATTGGCATTGATGTTT

Product: cytidine and deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLTTPPLAPKTVAALHRLGIRTLEELRQNGSVKAFLLLKASGLTLTKSTLWQLQSLLDDTLPQEMSQAHKARLLAELKNH
PPVAAFPSQEEMEHFMREALRQAEQSAADGEIPVGAVIVSDGKIIASAHNTCIADCNVSRHAEINALAQAGREIQNYRLD
GCDIYITLEPCAMCASALIQARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRGGILQEECRAVLSRFFQNKRKG

Sequences:

>Translated_239_residues
MLTTPPLAPKTVAALHRLGIRTLEELRQNGSVKAFLLLKASGLTLTKSTLWQLQSLLDDTLPQEMSQAHKARLLAELKNH
PPVAAFPSQEEMEHFMREALRQAEQSAADGEIPVGAVIVSDGKIIASAHNTCIADCNVSRHAEINALAQAGREIQNYRLD
GCDIYITLEPCAMCASALIQARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRGGILQEECRAVLSRFFQNKRKG
>Mature_239_residues
MLTTPPLAPKTVAALHRLGIRTLEELRQNGSVKAFLLLKASGLTLTKSTLWQLQSLLDDTLPQEMSQAHKARLLAELKNH
PPVAAFPSQEEMEHFMREALRQAEQSAADGEIPVGAVIVSDGKIIASAHNTCIADCNVSRHAEINALAQAGREIQNYRLD
GCDIYITLEPCAMCASALIQARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRGGILQEECRAVLSRFFQNKRKG

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=163, Percent_Identity=30.0613496932515, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19923945, Length=70, Percent_Identity=48.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=45.2054794520548, Blast_Score=134, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=32.4324324324324, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=37.1134020618557, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355527, Length=150, Percent_Identity=31.3333333333333, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 26088; Mature: 26088

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTPPLAPKTVAALHRLGIRTLEELRQNGSVKAFLLLKASGLTLTKSTLWQLQSLLDDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEHHHHHHHHHHHHHHH
LPQEMSQAHKARLLAELKNHPPVAAFPSQEEMEHFMREALRQAEQSAADGEIPVGAVIVS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
DGKIIASAHNTCIADCNVSRHAEINALAQAGREIQNYRLDGCDIYITLEPCAMCASALIQ
CCEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHH
ARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRGGILQEECRAVLSRFFQNKRKG
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTTPPLAPKTVAALHRLGIRTLEELRQNGSVKAFLLLKASGLTLTKSTLWQLQSLLDDT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCEEHHHHHHHHHHHHHHH
LPQEMSQAHKARLLAELKNHPPVAAFPSQEEMEHFMREALRQAEQSAADGEIPVGAVIVS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
DGKIIASAHNTCIADCNVSRHAEINALAQAGREIQNYRLDGCDIYITLEPCAMCASALIQ
CCEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHH
ARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRGGILQEECRAVLSRFFQNKRKG
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]