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The map label for this gene is dacC [H]

Identifier: 161869810

GI number: 161869810

Start: 840943

End: 842112

Strand: Reverse

Name: dacC [H]

Synonym: NMCC_0839

Alternate gene names: 161869810

Gene position: 842112-840943 (Counterclockwise)

Preceding gene: 161869812

Following gene: 161869803

Centisome position: 39.11

GC content: 49.06

Gene sequence:

>1170_bases
ATGACAGCACATAAAATCCTGCCCGTCCTGCTTTCCATCATCTTAGGCGTTTCTCATGCAACGGCTGCATCGCCCGCGCC
CAACAGACCGACGGCACACGCCGCCCCCACGCTCCAAACACCCGAAACCCTCACAGCGGCACACATCGTTATCGACCTTC
AAAGCAGACAGACTTTATCCGCCAAAAACATCAATACCCCTGTCGAACCGGCGGCACTAACCCAACTGATGACCGCATAT
CTGGTTTTCAAAAACATGAAATCGGGAAATATCCGATCTGAAGAAAACTTAAAAATACCCGAATCCGCATGGGCTTCAGA
AGGAAGCAGAATGTTTGTACGTCCCGGCGATACGGTCAGCACCGACAAACTCTTAAAAGGCATGATTGCACTATCCGCAA
ACGATGCCGCCCTAACCCTTGCCGGCCGGCTGGGCAACGGCTCGATTGAAAATTTTGTGCAACAAATGAACAAAGAAGCC
CGACGCTTGGGCATGAAGAACACTGTATTCAAAAATCCGACAGGCTTGAGTAGAGAAGGACAGGTTTCCACCGCCAAAGA
CCTCGCCCAGCTGTCTGAAGCATTGATGCGCGACTTTCCGGAATATTACCCGCTGTTTTCCATCAAATCTTTCAAATTCA
AAAATATAGAGCAAAACAACCGCAATATCCTTTTATATAGGGACAACAATGTAAACGGTCTGAAAGCCGGACACACAGAA
AGCGGCGGCTACAACCTTGCCGTGTCATACTCCGGCAACGGCAGGCACATCCTTGTCATCACATTGGGTTCGGAATCGGC
GGAAACACGCGCATCGGACAACAGCAAGCTGCTGAACTGGGCATTGCAAGCCTTCGATACGCCCAAAATATATCCGAAAG
GCAAAACCGTTGCCCAAATCCAAATTTCCGGAGGCAGCAAAAAAACCGTCCGCGCAGGCTTCCTCAAAGAAGCCTACATC
ACTCTGCCACATAAGGAAGCGAAAATGGCAGAACAGATTTTGGAAACCATACAGCCGATTCCCGCCCCGGTAAAAAAAGG
GCAAATTTTAGGAAAAATCAAAATCAGACAAAACGGATACACCATTGCCGAAAAAGAAATCGTCGCACTGGAAAATGTAG
AAAAAAGAAGCCGGTGGCAAAGGCTTTGGGTGCGTCTGACAGGGCAGTAA

Upstream 100 bases:

>100_bases
CATACGCCCAAGACGGCGCGAAATCAAGAAAAATCCGCCCGATCAGACACCCTAAGCGTATAATCGGCAGGCTGAAACAC
GCACACAATTAGAATATTTC

Downstream 100 bases:

>100_bases
TCCGCCGTTTCAAATATCCCGCTTTTCCAACAAATAAAGAAATGCCGTCTGAAACACGGTTCAGACGGCATAAAACAACA
GGGCAGTACGTATTGCATAC

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTAHKILPVLLSIILGVSHATAASPAPNRPTAHAAPTLQTPETLTAAHIVIDLQSRQTLSAKNINTPVEPAALTQLMTAY
LVFKNMKSGNIRSEENLKIPESAWASEGSRMFVRPGDTVSTDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEA
RRLGMKNTVFKNPTGLSREGQVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQNNRNILLYRDNNVNGLKAGHTE
SGGYNLAVSYSGNGRHILVITLGSESAETRASDNSKLLNWALQAFDTPKIYPKGKTVAQIQISGGSKKTVRAGFLKEAYI
TLPHKEAKMAEQILETIQPIPAPVKKGQILGKIKIRQNGYTIAEKEIVALENVEKRSRWQRLWVRLTGQ

Sequences:

>Translated_389_residues
MTAHKILPVLLSIILGVSHATAASPAPNRPTAHAAPTLQTPETLTAAHIVIDLQSRQTLSAKNINTPVEPAALTQLMTAY
LVFKNMKSGNIRSEENLKIPESAWASEGSRMFVRPGDTVSTDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEA
RRLGMKNTVFKNPTGLSREGQVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQNNRNILLYRDNNVNGLKAGHTE
SGGYNLAVSYSGNGRHILVITLGSESAETRASDNSKLLNWALQAFDTPKIYPKGKTVAQIQISGGSKKTVRAGFLKEAYI
TLPHKEAKMAEQILETIQPIPAPVKKGQILGKIKIRQNGYTIAEKEIVALENVEKRSRWQRLWVRLTGQ
>Mature_388_residues
TAHKILPVLLSIILGVSHATAASPAPNRPTAHAAPTLQTPETLTAAHIVIDLQSRQTLSAKNINTPVEPAALTQLMTAYL
VFKNMKSGNIRSEENLKIPESAWASEGSRMFVRPGDTVSTDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEAR
RLGMKNTVFKNPTGLSREGQVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQNNRNILLYRDNNVNGLKAGHTES
GGYNLAVSYSGNGRHILVITLGSESAETRASDNSKLLNWALQAFDTPKIYPKGKTVAQIQISGGSKKTVRAGFLKEAYIT
LPHKEAKMAEQILETIQPIPAPVKKGQILGKIKIRQNGYTIAEKEIVALENVEKRSRWQRLWVRLTGQ

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=364, Percent_Identity=36.2637362637363, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI87082022, Length=379, Percent_Identity=34.0369393139842, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786851, Length=343, Percent_Identity=32.9446064139942, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI87082054, Length=264, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42712; Mature: 42581

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHKILPVLLSIILGVSHATAASPAPNRPTAHAAPTLQTPETLTAAHIVIDLQSRQTLS
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEC
AKNINTPVEPAALTQLMTAYLVFKNMKSGNIRSEENLKIPESAWASEGSRMFVRPGDTVS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCC
TDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEARRLGMKNTVFKNPTGLSREG
HHHHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
QVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQNNRNILLYRDNNVNGLKAGHTE
CCHHHHHHHHHHHHHHHHCHHHCCCEEECCCEECCCCCCCCEEEEEECCCCCCCCCCCCC
SGGYNLAVSYSGNGRHILVITLGSESAETRASDNSKLLNWALQAFDTPKIYPKGKTVAQI
CCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
QISGGSKKTVRAGFLKEAYITLPHKEAKMAEQILETIQPIPAPVKKGQILGKIKIRQNGY
EECCCCCCHHHHHHHEEHEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCC
TIAEKEIVALENVEKRSRWQRLWVRLTGQ
EEEHHHHHHHHCHHHHHHHHEEEEEECCC
>Mature Secondary Structure 
TAHKILPVLLSIILGVSHATAASPAPNRPTAHAAPTLQTPETLTAAHIVIDLQSRQTLS
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEC
AKNINTPVEPAALTQLMTAYLVFKNMKSGNIRSEENLKIPESAWASEGSRMFVRPGDTVS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCC
TDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEARRLGMKNTVFKNPTGLSREG
HHHHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
QVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQNNRNILLYRDNNVNGLKAGHTE
CCHHHHHHHHHHHHHHHHCHHHCCCEEECCCEECCCCCCCCEEEEEECCCCCCCCCCCCC
SGGYNLAVSYSGNGRHILVITLGSESAETRASDNSKLLNWALQAFDTPKIYPKGKTVAQI
CCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEE
QISGGSKKTVRAGFLKEAYITLPHKEAKMAEQILETIQPIPAPVKKGQILGKIKIRQNGY
EECCCCCCHHHHHHHEEHEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCC
TIAEKEIVALENVEKRSRWQRLWVRLTGQ
EEEHHHHHHHHCHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]