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The map label for this gene is pgm [H]

Identifier: 161869736

GI number: 161869736

Start: 761933

End: 763315

Strand: Reverse

Name: pgm [H]

Synonym: NMCC_0756

Alternate gene names: 161869736

Gene position: 763315-761933 (Counterclockwise)

Preceding gene: 161869737

Following gene: 161869732

Centisome position: 35.45

GC content: 55.68

Gene sequence:

>1383_bases
ATGGCAAATATTGCCCGCGACATCTTCAAAGCCTACGACATCCGAGGCATTGTCGGCAAAACCCTGACTGACGATGCCGC
CTATCTCATCGGCAGGGCCATCGCCGCCAAAGCCGCCGAAAAAGGCATGACCCGCATCGCGCTCGGACGCGACGGACGCT
TGAGCGGTCCCGAACTGATGGAGCACATCCAACGCGGCTTTACCGACAGCGGTATCGGCGTCCTCAACGTCGGTATGGTC
GCCACGCCCATGCTCTATTTTGCCGCTATCAACGAATGCGGCGGCAGCGGCGTGATGATTACCGGCAGCCACAATCCGCC
TGATTACAACGGTTTCAAAATGATGCTCGGCGGCGACACGCTTGCCGGCGAAGCCATCCAAGAGCTTTTGTCCATCATTG
AAAAAGACGGTTTTGCTGCCGCCGGCAAACAAGGCAGCGTAACCGAAAAAGACATCTCCGGCGAATACCACAACCACATC
GTCGGACACGTCAAACTCAAACGCCCGATGAACATCGCCATTGACGCGGGCAACGGCGTGGGCGGCGCATTTGCAGGCAA
ACTCTACCGCGCTTTGAGGTGCGGCGTTACCGAACTTTTCTGCGACGTGGACGGCAATTTCCCCAACCACCATCCCGACC
CATCCAAACCCAAAAACCTGCAAGATTTGATTGCCGCGCTGAAAAACGGCGATGCCGAAATCGGCTTGGCGTTTGACGGC
GATGCCGACCGCTTGGGCGTGGTTACCAAAGACGGCAACATTATTTATCCCGACCGCCAACTGATGCTGTTCGCGCAAGA
CGTGTTGAGCCGCAACCCCGGCGCGAAAGTCATCTTCGACGTGAAGTCCACCCGCCTGCTTGCCCCGTGGATTAAAGAAC
ACGGCGGCGAAGCCATAATGGAAAAAACCGGCCACAGCTTTATCAAATCCTCCATGAAAAAAACCGGCGCACTCGTCGCC
GGCGAAATGAGCGGACACATCTTCTTCAAAGAACGCTGGTTCGGATTCGACGACGGTCTGTACGCCGGCGCACGCCTCTT
GGAAATCCTGTCTGCCTCCGATAATCCGTCCGAAGTGTTAAACAACCTGCCGCAAAGCATTTCCACGCCCGAACTCAACA
TTGACCTGCCGGAAGGCAGCAACGGCCACAAAGTGATTGAAGAGCTGGCTGCCAATGCCAAGTTTGAAGGTGCGACCGAA
ATCATCACCATCGACGGTCTGCGCGTTGAATTTCCCGACGGCTTCGGTCTGATGCGTGCTTCCAATACCACGCCGATTCT
GGTGTTGCGTTTTGAGGCAGATACGCAAGAAGCCATCGAGCGGATTCAAAACCAATTCAAAGCCGTCATCGAAAGCAATC
CGAATCTAATCTGGCCTCTGTAA

Upstream 100 bases:

>100_bases
CAAGCACATATGCCGTCTGAACACCTCCCGCAAGCCTTCGGACAATGTTGCAACGTGTTAAAATAGCCTCCTTTCCTGAA
ACCACAACAAGGAAACCATC

Downstream 100 bases:

>100_bases
ACACAGGAAAAATGCTTAATCAAATCTTGGTAGATTGGATTTGGCTTAAAAATCTCCGCGTCCGCTCATGTTTGGGATGG
TTGAACAAATCTTGCGGGCT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MANIARDIFKAYDIRGIVGKTLTDDAAYLIGRAIAAKAAEKGMTRIALGRDGRLSGPELMEHIQRGFTDSGIGVLNVGMV
ATPMLYFAAINECGGSGVMITGSHNPPDYNGFKMMLGGDTLAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYHNHI
VGHVKLKRPMNIAIDAGNGVGGAFAGKLYRALRCGVTELFCDVDGNFPNHHPDPSKPKNLQDLIAALKNGDAEIGLAFDG
DADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPGAKVIFDVKSTRLLAPWIKEHGGEAIMEKTGHSFIKSSMKKTGALVA
GEMSGHIFFKERWFGFDDGLYAGARLLEILSASDNPSEVLNNLPQSISTPELNIDLPEGSNGHKVIEELAANAKFEGATE
IITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQEAIERIQNQFKAVIESNPNLIWPL

Sequences:

>Translated_460_residues
MANIARDIFKAYDIRGIVGKTLTDDAAYLIGRAIAAKAAEKGMTRIALGRDGRLSGPELMEHIQRGFTDSGIGVLNVGMV
ATPMLYFAAINECGGSGVMITGSHNPPDYNGFKMMLGGDTLAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYHNHI
VGHVKLKRPMNIAIDAGNGVGGAFAGKLYRALRCGVTELFCDVDGNFPNHHPDPSKPKNLQDLIAALKNGDAEIGLAFDG
DADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPGAKVIFDVKSTRLLAPWIKEHGGEAIMEKTGHSFIKSSMKKTGALVA
GEMSGHIFFKERWFGFDDGLYAGARLLEILSASDNPSEVLNNLPQSISTPELNIDLPEGSNGHKVIEELAANAKFEGATE
IITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQEAIERIQNQFKAVIESNPNLIWPL
>Mature_459_residues
ANIARDIFKAYDIRGIVGKTLTDDAAYLIGRAIAAKAAEKGMTRIALGRDGRLSGPELMEHIQRGFTDSGIGVLNVGMVA
TPMLYFAAINECGGSGVMITGSHNPPDYNGFKMMLGGDTLAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYHNHIV
GHVKLKRPMNIAIDAGNGVGGAFAGKLYRALRCGVTELFCDVDGNFPNHHPDPSKPKNLQDLIAALKNGDAEIGLAFDGD
ADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPGAKVIFDVKSTRLLAPWIKEHGGEAIMEKTGHSFIKSSMKKTGALVAG
EMSGHIFFKERWFGFDDGLYAGARLLEILSASDNPSEVLNNLPQSISTPELNIDLPEGSNGHKVIEELAANAKFEGATEI
ITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQEAIERIQNQFKAVIESNPNLIWPL

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=439, Percent_Identity=31.4350797266515, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1789566, Length=471, Percent_Identity=25.0530785562633, Blast_Score=88, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17864244, Length=460, Percent_Identity=23.2608695652174, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 49550; Mature: 49419

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIARDIFKAYDIRGIVGKTLTDDAAYLIGRAIAAKAAEKGMTRIALGRDGRLSGPELM
CCHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
EHIQRGFTDSGIGVLNVGMVATPMLYFAAINECGGSGVMITGSHNPPDYNGFKMMLGGDT
HHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCC
LAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYHNHIVGHVKLKRPMNIAIDAGNGV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHCCEEEEEEECCCCEEEEECCCCC
GGAFAGKLYRALRCGVTELFCDVDGNFPNHHPDPSKPKNLQDLIAALKNGDAEIGLAFDG
CHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
DADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPGAKVIFDVKSTRLLAPWIKEHGGEAIM
CCCCEEEEECCCCEECCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHHHHHCCCHHHH
EKTGHSFIKSSMKKTGALVAGEMSGHIFFKERWFGFDDGLYAGARLLEILSASDNPSEVL
HHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHH
NNLPQSISTPELNIDLPEGSNGHKVIEELAANAKFEGATEIITIDGLRVEFPDGFGLMRA
HHCCHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCEEEE
SNTTPILVLRFEADTQEAIERIQNQFKAVIESNPNLIWPL
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
ANIARDIFKAYDIRGIVGKTLTDDAAYLIGRAIAAKAAEKGMTRIALGRDGRLSGPELM
CHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHH
EHIQRGFTDSGIGVLNVGMVATPMLYFAAINECGGSGVMITGSHNPPDYNGFKMMLGGDT
HHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCCC
LAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYHNHIVGHVKLKRPMNIAIDAGNGV
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHCCEEEEEEECCCCEEEEECCCCC
GGAFAGKLYRALRCGVTELFCDVDGNFPNHHPDPSKPKNLQDLIAALKNGDAEIGLAFDG
CHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
DADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPGAKVIFDVKSTRLLAPWIKEHGGEAIM
CCCCEEEEECCCCEECCCHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHHHHHCCCHHHH
EKTGHSFIKSSMKKTGALVAGEMSGHIFFKERWFGFDDGLYAGARLLEILSASDNPSEVL
HHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHH
NNLPQSISTPELNIDLPEGSNGHKVIEELAANAKFEGATEIITIDGLRVEFPDGFGLMRA
HHCCHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCEEEE
SNTTPILVLRFEADTQEAIERIQNQFKAVIESNPNLIWPL
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]