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The map label for this gene is argC

Identifier: 161751104

GI number: 161751104

Start: 217734

End: 218783

Strand: Reverse

Name: argC

Synonym: ST0195

Alternate gene names: 161751104

Gene position: 218783-217734 (Counterclockwise)

Preceding gene: 15920376

Following gene: 15920373

Centisome position: 8.12

GC content: 35.9

Gene sequence:

>1050_bases
ATGATAAGAGTTGCTGTAATAGGAGGTTCAGGTTATACTGGTGGAGAATTGCTAAGAATTCTGGCAGTTCACCCCAAAAT
AGAAGTAACGTATGTAACATCTAGAGAATATGCCGGTAAACCCATAACATTAGTACATCCAAATTTAAGAGGATTTTATA
ATATGAATTTTTCACAGTTTTCATTTGATAAACTAGGAGATAAAGCGGATGCTGTATTTCTAGGGTTACCGCATAAAGTT
TCATTAGAATATGTACCAAAGATTCTAGAAATGGGAATTCAAGTAATTGATTTAAGTGCAGATTTTAGGTTAAAAGATCC
TACTCTATATAAAATATGGTATGGTTATGAGCATCCATACCCAGATTTACTGAAAAAAGCTGTGTATGGCTTACCAGAAC
TTCACTATGAAGAACTTAAAAATGCAAAACTTATCGCTTCTCCAGGCTGTAATGCTACTGCAACTATATTAGCTGGTGCT
CCTTTAGTTGCATCAAGTCTATTAGAGACTTACAAATTAATCAGCGATGTAAAAGTTGGAAGTAGTGAAGGAGGTGCGAA
ACCTCATGAAGGTAGCCATCATCCAGAAAGACAAAATGCAATAAGACCTTATGAGGCCGATGGGCATAGACACGCAGCTG
AAGCTGAGCAAGAACTTAGTTTAATAGCAAAAAGGGATGTAAAAGTAAGTTTGGTTCCTCACGCCGTTAGTAGTGTGAGA
GGTGCTTTGGCTTCAGTTCATGGTTGGCTAAGTAGTGATATAAGCGAAATGGATATGTGGAAGAAATCCATAGAATTCTA
TAAAGGAAGAAAATTCATACGTATAATAAGGAGTAATATTCATCCTTATCCAGACCCAAAATTTGTTATAGGTAGTAATT
TTGCAGATATAGGTTTTGCAATAGAAAAAAGAATGCAAAGAATAACAATGTTTTCTGCAATAGATAACTTGATGAAAGGT
GCTGCTGGTCAAGCAGTACAAGCTTTTAACATATCAAGAGGTTTTGAAGAAGATGAGGGTTTAAGAATACCTCCTCTGAG
GCCTGCTTAA

Upstream 100 bases:

>100_bases
TTTCTTCTAAGAATTTCTTCAATTCGTCTGTTGTTATACTCATAATATAATACTATATATGCTTAAATTACTTATAATCC
TATTGCTTTATGGTCAAAAG

Downstream 100 bases:

>100_bases
AATGATAGTTATAAAAGCCGGAGGAAGAGTAATAAAAAATAATTTAGATGGTATTATTGAAAGTTTATCTAATGTAGGAG
AACAAGCTATATTTGTTCAT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde/N-acetyl-aminoadipate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MIRVAVIGGSGYTGGELLRILAVHPKIEVTYVTSREYAGKPITLVHPNLRGFYNMNFSQFSFDKLGDKADAVFLGLPHKV
SLEYVPKILEMGIQVIDLSADFRLKDPTLYKIWYGYEHPYPDLLKKAVYGLPELHYEELKNAKLIASPGCNATATILAGA
PLVASSLLETYKLISDVKVGSSEGGAKPHEGSHHPERQNAIRPYEADGHRHAAEAEQELSLIAKRDVKVSLVPHAVSSVR
GALASVHGWLSSDISEMDMWKKSIEFYKGRKFIRIIRSNIHPYPDPKFVIGSNFADIGFAIEKRMQRITMFSAIDNLMKG
AAGQAVQAFNISRGFEEDEGLRIPPLRPA

Sequences:

>Translated_349_residues
MIRVAVIGGSGYTGGELLRILAVHPKIEVTYVTSREYAGKPITLVHPNLRGFYNMNFSQFSFDKLGDKADAVFLGLPHKV
SLEYVPKILEMGIQVIDLSADFRLKDPTLYKIWYGYEHPYPDLLKKAVYGLPELHYEELKNAKLIASPGCNATATILAGA
PLVASSLLETYKLISDVKVGSSEGGAKPHEGSHHPERQNAIRPYEADGHRHAAEAEQELSLIAKRDVKVSLVPHAVSSVR
GALASVHGWLSSDISEMDMWKKSIEFYKGRKFIRIIRSNIHPYPDPKFVIGSNFADIGFAIEKRMQRITMFSAIDNLMKG
AAGQAVQAFNISRGFEEDEGLRIPPLRPA
>Mature_349_residues
MIRVAVIGGSGYTGGELLRILAVHPKIEVTYVTSREYAGKPITLVHPNLRGFYNMNFSQFSFDKLGDKADAVFLGLPHKV
SLEYVPKILEMGIQVIDLSADFRLKDPTLYKIWYGYEHPYPDLLKKAVYGLPELHYEELKNAKLIASPGCNATATILAGA
PLVASSLLETYKLISDVKVGSSEGGAKPHEGSHHPERQNAIRPYEADGHRHAAEAEQELSLIAKRDVKVSLVPHAVSSVR
GALASVHGWLSSDISEMDMWKKSIEFYKGRKFIRIIRSNIHPYPDPKFVIGSNFADIGFAIEKRMQRITMFSAIDNLMKG
AAGQAVQAFNISRGFEEDEGLRIPPLRPA

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=34.1040462427746, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320913, Length=348, Percent_Identity=29.0229885057471, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_SULTO (Q976J5)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376043.2
- ProteinModelPortal:   Q976J5
- SMR:   Q976J5
- GeneID:   1458080
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0195
- NMPDR:   fig|273063.1.peg.211
- HOGENOM:   HBG294213
- ProtClustDB:   PRK00436
- BioCyc:   STOK273063:ST0195-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38700; Mature: 38700

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 150-150

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVAVIGGSGYTGGELLRILAVHPKIEVTYVTSREYAGKPITLVHPNLRGFYNMNFSQF
CEEEEEECCCCCCHHHHHHHEEECCCEEEEEEECCCCCCCCEEEECCCCCEEEECCCCCC
SFDKLGDKADAVFLGLPHKVSLEYVPKILEMGIQVIDLSADFRLKDPTLYKIWYGYEHPY
CHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCEECCCEEEEEEECCCCCC
PDLLKKAVYGLPELHYEELKNAKLIASPGCNATATILAGAPLVASSLLETYKLISDVKVG
HHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
SSEGGAKPHEGSHHPERQNAIRPYEADGHRHAAEAEQELSLIAKRDVKVSLVPHAVSSVR
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHH
GALASVHGWLSSDISEMDMWKKSIEFYKGRKFIRIIRSNIHPYPDPKFVIGSNFADIGFA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEEECCCCHHHHHH
IEKRMQRITMFSAIDNLMKGAAGQAVQAFNISRGFEEDEGLRIPPLRPA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEECCCCCCC
>Mature Secondary Structure
MIRVAVIGGSGYTGGELLRILAVHPKIEVTYVTSREYAGKPITLVHPNLRGFYNMNFSQF
CEEEEEECCCCCCHHHHHHHEEECCCEEEEEEECCCCCCCCEEEECCCCCEEEECCCCCC
SFDKLGDKADAVFLGLPHKVSLEYVPKILEMGIQVIDLSADFRLKDPTLYKIWYGYEHPY
CHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCEECCCEEEEEEECCCCCC
PDLLKKAVYGLPELHYEELKNAKLIASPGCNATATILAGAPLVASSLLETYKLISDVKVG
HHHHHHHHHCCCCHHHHHHCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCC
SSEGGAKPHEGSHHPERQNAIRPYEADGHRHAAEAEQELSLIAKRDVKVSLVPHAVSSVR
CCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHH
GALASVHGWLSSDISEMDMWKKSIEFYKGRKFIRIIRSNIHPYPDPKFVIGSNFADIGFA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCEEECCCCHHHHHH
IEKRMQRITMFSAIDNLMKGAAGQAVQAFNISRGFEEDEGLRIPPLRPA
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479