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The map label for this gene is gcp [H]

Identifier: 161611186

GI number: 161611186

Start: 252951

End: 253967

Strand: Direct

Name: gcp [H]

Synonym: BAS0247

Alternate gene names: 161611186

Gene position: 252951-253967 (Clockwise)

Preceding gene: 49183278

Following gene: 49183281

Centisome position: 4.84

GC content: 40.22

Gene sequence:

>1017_bases
ATGGAAAAAAATACGATTATACTTGGTATTGAAACAAGTTGTGATGAAACAGCAGTAGCGGTTGTTAAAAATGGAACGGA
AATTATTGCGAATGTCGTTGCATCACAAATTGAAAGTCATAAACGTTTTGGCGGAGTTGTACCAGAGATTGCATCTCGTC
ATCATGTAGAAGAAATTACAGTTGTGTTAGAAGAAGCTTTAAAAGAAGCGAATATCACATTTGATGATATTGATGCAATT
GCTGTAACAGAAGGACCTGGTTTAGTAGGAGCACTTCTAATAGGGGTAAATGCAGCGAAAGCAGTGGCATTTGCACATGA
TATCCCTCTAGTTGGCGTTCATCATATCGCTGGCCACATTTATGCGAACCGTTTAGTAAAAGAAGTTCAATTCCCATTAC
TATCACTTGTTGTGTCTGGTGGACATACAGAGCTTGTTTATATGAAAGAACATGGTTCATTTGAAGTAATTGGTGAAACG
CGAGATGATGCAGCAGGAGAAGCATATGATAAAGTAGCTCGTACGTTATCTATGCCATATCCAGGGGGGCCTCATATTGA
TCGCCTTGCACATGAAGGGAAACCAACAATCGATTTACCTCGTGCATGGCTTGAACCTGATTCGTATGATTTCAGTTTTA
GCGGATTAAAATCAGCAGTTATCAACACTGTGCATAACGCAAAACAACGCGGTATAGAGATTGCACCGGAAGATTTAGCG
GCAAGTTTCCAAGAGAGTGTCATTGACGTACTAGTAACGAAAGCATCTCGTGCAGCGGATGCTTATAACGTAAAGCAAGT
GCTTCTTGCTGGTGGAGTGGCTGCTAATAAAGGGCTTCGTGCACGCTTAGAAACAGAATTTGCACAAAAAGAAAATGTAG
AGCTAATTATTCCTCCTCTATCTTTATGCACAGATAATGCAGCAATGATTGCAGCGGCAGGTACAATTGCATATGAACAA
GGAAAACGTGCTACATTAGCTTTAAATGCAAATCCAGGATTAGATATCGAAGCATAG

Upstream 100 bases:

>100_bases
AACAGTTATACAGAAAATACGGATTTCAAAATGGTGGAATTCGTAAACGATACTATGCAGACAATCAGGAAGATGGTCTC
GTAATGTGGGTGAATATATA

Downstream 100 bases:

>100_bases
TTATGCACAAAATTAACCACAGCTTGTGGATAAAACCCATATTATCTGTTGATAATATGGGTTTTATTGTGTATATAAAA
TGTTGATAACTTTTTAGTTA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLETEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA

Sequences:

>Translated_338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLETEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA
>Mature_338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLETEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI8923380, Length=325, Percent_Identity=36.6153846153846, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI116812636, Length=333, Percent_Identity=33.3333333333333, Blast_Score=165, Evalue=7e-41,
Organism=Escherichia coli, GI1789445, Length=328, Percent_Identity=43.5975609756098, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=32.3076923076923, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=32.2085889570552, Blast_Score=147, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6320099, Length=351, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=30.4597701149425, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI20129063, Length=361, Percent_Identity=31.0249307479224, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=31.6109422492401, Blast_Score=154, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35973; Mature: 35973

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEIT
CCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHI
HHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
YANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
PGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
CCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHH
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLETEFAQKENVELIIPPL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCH
SLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
HHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEIT
CCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHI
HHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
YANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
PGGPHIDRLAHEGKPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
CCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHH
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLETEFAQKENVELIIPPL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEECCH
SLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
HHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA