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The map label for this gene is argD

Identifier: 161611180

GI number: 161611180

Start: 3973095

End: 3974255

Strand: Reverse

Name: argD

Synonym: BAS4037

Alternate gene names: 161611180

Gene position: 3974255-3973095 (Counterclockwise)

Preceding gene: 49187036

Following gene: 49187034

Centisome position: 76.01

GC content: 38.67

Gene sequence:

>1161_bases
ATGATAAGTCATCTTTTTCAAACGTATGGGAGAAGAACTGTTGAGTTTGTAAAGGGGAATGGAACGAAAGTCATTGATAA
CAACGGTAAACAATATTTAGATTTCACATCAGGGATTGGTGTATGTAATTTAGGGCATTGCCATCCTACTGTTATGAAAG
CGGTACAAGAGCAACTTAATGATATATGGCATATATCTAATTTGTTTACAAATAGCTTACAAGAAGAAGTCGCGTCATTA
TTAACAGAAAATATAGCATTAGATTATGTGTTCTTCTGTAATAGCGGGGCAGAGGCGAATGAAGCAGCTTTGAAGCTAGC
CCGTAAGCATACTGGAAAATCTCTCGTCGTAACGTGTGAGCAGTCTTTTCACGGTAGAACATTCGGAACGATGAGTGCGA
CGGGACAAAATAAAGTGAAAGAAGGGTTTGGTCCGCTCCTTCCGTCTTTTTTACATACTCCATTTAACGATATAAAGGCG
CTCAAGGAAGTAATGAATGAAGAAGTTGCGGCAGTAATGGTAGAAGTTGTTCAAGGAGAGGGAGGAGTCATACCTGCTGA
TCTATCCTTTTTGAAAGAGATTGAAACATTATGTAAGAAGTTTGGTTCCTTATTTATTATAGACGAAGTACAAACAGGGA
TCGGAAGAACAGGTACATTATTTGCTTACGAACAAATGGGAATAGATCCTCATATCGTTACTACCGCTAAGGCGCTTGGA
AATGGGATTCCTGTCGGAGCAATGATTGGCCGGAAAGAACTCGGAACGTCGTTCACTGCAGGATCGCACGGTTCAACGTT
TGGCGGAAATTATGTTGCAATGGCTGCAGCGAAAGAAGTATTACAAGTAAGTAAAAGACTATCGTTTTTAAAAGAAGTAC
AAGAAAAGGGCGAGTACGTATTACAGAAGTTGCAAGAGGAATTACAACATGTCGAATGTATTCAAAATATACGTGGTAAG
GGCCTTATGGTTGGAATTGAATGTACGCATGAAGTTGCAAGTTTTATAGAGCAACTAGAAAAAGAGGGACTACTCGTATT
ACAAGCAGGGCCTAATGTGATAAGACTATTACCGCCGCTCATTGTAACGAATGAAGAGTTAGAACAGGCAGTATATATGA
TAAAAAAAGTAGTTTGTACAAAAAATGTATCAATTATATAA

Upstream 100 bases:

>100_bases
TGGGAGTGCAAAAGATAAGTATCGTAAATGGTACAAAAGATTTTACTGAAGATACAGGAGAATGTATTGGAATGACGGTA
ACGAGGGGAGTGAGTATCGT

Downstream 100 bases:

>100_bases
GGGGGAAATTTCATGTCAACTGTACAAGTACCGAAGTTAAATACGAAAGATCTTTTAACACTAGAAGAATTAACGCAAGA
AGAAATCATTTCTTTAATTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRLSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMVGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII

Sequences:

>Translated_386_residues
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRLSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMVGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII
>Mature_386_residues
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRLSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMVGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPLIVTNEELEQAVYMIKKVVCTKNVSII

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=31.9587628865979, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=30.4147465437788, Blast_Score=181, Evalue=8e-46,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.2225913621262, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=27.6029055690073, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=27.6960784313726, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=27.7777777777778, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI226442705, Length=413, Percent_Identity=26.634382566586, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI188536080, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI38679950, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI38679946, Length=415, Percent_Identity=22.8915662650602, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1789759, Length=376, Percent_Identity=40.6914893617021, Blast_Score=300, Evalue=9e-83,
Organism=Escherichia coli, GI1788044, Length=361, Percent_Identity=41.8282548476454, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI145693181, Length=400, Percent_Identity=36, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=33.0808080808081, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=32.6424870466321, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786349, Length=277, Percent_Identity=32.129963898917, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786991, Length=417, Percent_Identity=27.3381294964029, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=34.8958333333333, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=32.0276497695853, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=376, Percent_Identity=30.5851063829787, Blast_Score=181, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=410, Percent_Identity=30.4878048780488, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI71981843, Length=193, Percent_Identity=31.0880829015544, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=23.4624145785877, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=35.7142857142857, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.3333333333333, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6324386, Length=346, Percent_Identity=25.7225433526012, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=370, Percent_Identity=25.4054054054054, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=31.0880829015544, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI161085790, Length=408, Percent_Identity=31.3725490196078, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574759, Length=408, Percent_Identity=31.3725490196078, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=31.1274509803922, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=25.1196172248804, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=25.1196172248804, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=25.1196172248804, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ARGD_BACAN (Q81M98)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_846584.1
- RefSeq:   YP_022688.1
- ProteinModelPortal:   Q81M98
- SMR:   Q81M98
- IntAct:   Q81M98
- EnsemblBacteria:   EBBACT00000012225
- EnsemblBacteria:   EBBACT00000016219
- EnsemblBacteria:   EBBACT00000023217
- GeneID:   1087573
- GeneID:   2816449
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4352
- KEGG:   bar:GBAA_4352
- KEGG:   bat:BAS4037
- TIGR:   BA_4352
- TIGR:   GBAA_4352
- GeneTree:   EBGT00070000031861
- HOGENOM:   HBG725944
- OMA:   VKEGFGP
- ProtClustDB:   PRK02936
- BioCyc:   BANT260799:BAS4037-MONOMER
- BioCyc:   BANT261594:GBAA4352-MONOMER
- BRENDA:   2.6.1.11
- GO:   GO:0005737
- HAMAP:   MF_01107
- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF19
- TIGRFAMs:   TIGR00707

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.11

Molecular weight: Translated: 42179; Mature: 42179

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: BINDING 123-123 BINDING 126-126 BINDING 265-265 BINDING 266-266

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRLSFLKEVQEKGEYV
CCCCHHHHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQKLQEELQHVECIQNIRGKGLMVGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCH
IVTNEELEQAVYMIKKVVCTKNVSII
HCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MISHLFQTYGRRTVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAKEVLQVSKRLSFLKEVQEKGEYV
CCCCHHHHHCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQKLQEELQHVECIQNIRGKGLMVGIECTHEVASFIEQLEKEGLLVLQAGPNVIRLLPPL
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCEEEEECCCCHHHHCCCH
IVTNEELEQAVYMIKKVVCTKNVSII
HCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629