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The map label for this gene is 161525417

Identifier: 161525417

GI number: 161525417

Start: 2460515

End: 2461438

Strand: Reverse

Name: 161525417

Synonym: Bmul_2247

Alternate gene names: NA

Gene position: 2461438-2460515 (Counterclockwise)

Preceding gene: 161525419

Following gene: 161525415

Centisome position: 71.38

GC content: 67.42

Gene sequence:

>924_bases
ATGGCAACCGCCTTCTATACGCACCCCGACTGCATGCTGCACGAGATGGGGCAGTGGCATCCGGAATGCCCGGCCCGGCT
GTCGGCGATCCAGGATCAGCTGATCGCGAGCCGCATCGACGATCTGATCGTGCACGAAACGGCGCCGTTCGCGAGCGAAG
TCGCGCTCGGCCGCGTGCATACGCAGGCGCACATCGACTATCTGCGCGGGCTGACGCCCGTCGAGGGCTACGTCGAGATC
GACCCCGATACGCTGATGAACCGCGACACGTGGCGCGCCGCATTGCGCGCGGCCGGCGCCGCGGTCGCGGCGACCGACGC
CGTGATCGAGGGCCGCTACGCGAACGCGTTCTGCAGCGTGCGTCCGCCCGGCCATCATGCCGAGCCTGCGCGCGCGATGG
GCTTCTGCTTCTTCAACAACGTCGCGGTCGCGGCGCGGCACGCGCTCGACGTGCACGGCCTCGAGCGCGTCGCGATCGTC
GATTTCGACGTGCATCACGGCAACGGCACCGAGGCCGCGTTCGCGAACGATCCGCGCGTGCTGATGTGCAGCTTCTTCCA
GCATCCGCTGTATCCGTTCTCGGGCGTCGATCATCAGGCGCCGAACATGGTGAACCTGCCGATGCCCGCGCGCAGCAACG
GGATGGCGATCCGCGAGGCGGTCGACATGTTCTGGCTGCCGCGTCTCGACGCGTTCAAGCCGCAGATGCTGTTCGTATCC
GCGGGCTTCGATGCGCATCGCGAGGACGACATCGGCAATCTCGGTCTCGTTGAAGCCGACTTTGAGTGGCTCACCGCACA
GATCGTCGACGTTGCGCGCCGGCATGCGCAGGGCCGCATCGTCAGCTGTCTCGAGGGCGGCTACAACCTATCCGCGCTCG
GGCGCAGCGTCGTCGCGCATCTGCGCGTGCTCGCCGGCATCTGA

Upstream 100 bases:

>100_bases
AGCGGGCGCGCGATGTGGTAAGTTAGCGGCGAATTCGCGGCAGACGATGGACATCATTGAAGGAGACCTGCGGTGCATCC
AGCGCTGCAGATGACACGTT

Downstream 100 bases:

>100_bases
CGGCCCGCGCCCGGCCCGCAGTCAGCGCGCCGGCACGCGCGCATCTATCCAGCCGATCAGCGCATCGATCACGCGCTCGC
GCTCGATGTCGTTCATCGTT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MATAFYTHPDCMLHEMGQWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVHTQAHIDYLRGLTPVEGYVEI
DPDTLMNRDTWRAALRAAGAAVAATDAVIEGRYANAFCSVRPPGHHAEPARAMGFCFFNNVAVAARHALDVHGLERVAIV
DFDVHHGNGTEAAFANDPRVLMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGI

Sequences:

>Translated_307_residues
MATAFYTHPDCMLHEMGQWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVHTQAHIDYLRGLTPVEGYVEI
DPDTLMNRDTWRAALRAAGAAVAATDAVIEGRYANAFCSVRPPGHHAEPARAMGFCFFNNVAVAARHALDVHGLERVAIV
DFDVHHGNGTEAAFANDPRVLMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGI
>Mature_306_residues
ATAFYTHPDCMLHEMGQWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVHTQAHIDYLRGLTPVEGYVEID
PDTLMNRDTWRAALRAAGAAVAATDAVIEGRYANAFCSVRPPGHHAEPARAMGFCFFNNVAVAARHALDVHGLERVAIVD
FDVHHGNGTEAAFANDPRVLMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVSA
GFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGI

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=307, Percent_Identity=35.8306188925081, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI20070354, Length=330, Percent_Identity=36.0606060606061, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI17158039, Length=331, Percent_Identity=32.6283987915408, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI30795204, Length=331, Percent_Identity=32.6283987915408, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI30795202, Length=331, Percent_Identity=32.6283987915408, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI226529806, Length=327, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI153085395, Length=329, Percent_Identity=32.8267477203647, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI62750347, Length=238, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI62750349, Length=238, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI169234807, Length=238, Percent_Identity=36.5546218487395, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI148539870, Length=238, Percent_Identity=36.5546218487395, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI217272877, Length=268, Percent_Identity=25.7462686567164, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13128862, Length=275, Percent_Identity=21.8181818181818, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=33.6601307189542, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=33.6601307189542, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=33.6601307189542, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193209491, Length=324, Percent_Identity=32.7160493827161, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25154020, Length=297, Percent_Identity=32.3232323232323, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17537347, Length=308, Percent_Identity=32.1428571428571, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25154022, Length=299, Percent_Identity=32.4414715719064, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534739, Length=328, Percent_Identity=25.3048780487805, Blast_Score=88, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324307, Length=318, Percent_Identity=32.0754716981132, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325141, Length=301, Percent_Identity=24.5847176079734, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323999, Length=287, Percent_Identity=23.3449477351916, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=25.5681818181818, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=317, Percent_Identity=35.9621451104101, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24642146, Length=317, Percent_Identity=35.9621451104101, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24642142, Length=317, Percent_Identity=35.9621451104101, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24642144, Length=317, Percent_Identity=35.9621451104101, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24641720, Length=341, Percent_Identity=31.3782991202346, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281360801, Length=341, Percent_Identity=31.3782991202346, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281360799, Length=341, Percent_Identity=31.3782991202346, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24657891, Length=273, Percent_Identity=25.2747252747253, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649807, Length=296, Percent_Identity=26.3513513513513, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33711; Mature: 33579

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAFYTHPDCMLHEMGQWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVH
CCCEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TQAHIDYLRGLTPVEGYVEIDPDTLMNRDTWRAALRAAGAAVAATDAVIEGRYANAFCSV
HHHHHHHHHCCCCCCCEEEECHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEC
RPPGHHAEPARAMGFCFFNNVAVAARHALDVHGLERVAIVDFDVHHGNGTEAAFANDPRV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEECCCCCE
LMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
EEEHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LRVLAGI
HHHHHCC
>Mature Secondary Structure 
ATAFYTHPDCMLHEMGQWHPECPARLSAIQDQLIASRIDDLIVHETAPFASEVALGRVH
CCEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TQAHIDYLRGLTPVEGYVEIDPDTLMNRDTWRAALRAAGAAVAATDAVIEGRYANAFCSV
HHHHHHHHHCCCCCCCEEEECHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEC
RPPGHHAEPARAMGFCFFNNVAVAARHALDVHGLERVAIVDFDVHHGNGTEAAFANDPRV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEECCCCCE
LMCSFFQHPLYPFSGVDHQAPNMVNLPMPARSNGMAIREAVDMFWLPRLDAFKPQMLFVS
EEEHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDIGNLGLVEADFEWLTAQIVDVARRHAQGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LRVLAGI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]