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The map label for this gene is degP [H]

Identifier: 161525344

GI number: 161525344

Start: 2390963

End: 2392435

Strand: Reverse

Name: degP [H]

Synonym: Bmul_2174

Alternate gene names: 161525344

Gene position: 2392435-2390963 (Counterclockwise)

Preceding gene: 161525345

Following gene: 161525343

Centisome position: 69.38

GC content: 68.77

Gene sequence:

>1473_bases
ATGATGAAAATCACGCTGCGCAAATGGCTTGCGGCGGCGGCGCTGTCCGCCTGCCTGCCGCTCGTGCCGCACACCGCGGC
CGCCGCGCCGGTCCCCGCTGCCAGCCTGCCCGATTTCGCCGATCTGGTCGAAAAGGTCGGGCCGGCCGTCGTGAACATCC
GCACCACCGCGAACGTGCCGTCCGGCCCGCGCGGCGGGCTGCCGCCCGGTTTCGACAACGGCGACATGTCGGAATTCTTC
CGGCGCTTCTTCGGCATTCCGCTGCCGCAGGCGCCCGGCAATCCCAAAAACGCACCGGCGCCCGACAACGCGCCCGACAC
CGAGCAGAACCGCGGCGTCGGCTCGGGCTTCATCGTGTCGGCCGACGGCTACGTGATGACGAACGCGCACGTCGTCGACG
ACGCGGACACGATCTACGTGACGCTCACCGACAAGCGCGAATTCAAGGCGAAGCTGATCGGCGTCGACGACCGCACCGAC
GTCGCGGTCGTGAAGATCCAGGCGTCGAATCTGCCGGTCGTCGCGATCGGCGATTCCAACAAGGTGCGCGTCGGCGAGTG
GGTCGTCGCGATCGGCTCGCCGTTCGGCCTCGACAACACGGTCACGGCCGGCATCGTCAGCTCGAAGAGCCGCAACACCG
GCGATTACCTGCCGTTCATCCAGACCGACGTCGCCGTGAACCCCGGCAACTCGGGCGGCCCGCTGATCAACATGCAGGGC
GAGGTGATCGGCATCAACTCGCAGATCTACAGCCGCACCGGCGGCTTCATGGGCATTTCGTTCGCGATCCCGATCGACGA
GGCGATGCGCGTCGCCGATCAGCTGAAAGCGACCGGCAAGGTCACGCGCGGCCGGATCGCGGTCGCCATCGGCGAGGTGA
CGAAGGACGTGGCCGACTCGATCGGACTGCCGAAGGCAGAAGGCGCGCTCGTCAGCAGCGTCGAGCCGGGCGGCCCGGCC
GACAAGGCGGGCGTCCAGCCGGGCGACATCATCCTGAAGTTCAACGGCCGCGCCGTCGATACGGCATCGGACCTGCCGCG
CATGGTCGGCGACACGAAGCCGGGCACGAAGGCGACCGTCACCGTATGGCGCAAGGGTCAGGCGCGCGATCTGCCGATCA
CGATCGCGGAGACGCCGTCCGATACGACCGCGAAGGCCGATCCGCGCAAGAACGCGCCGCAGAAGCCGCGCCAGAGCAAT
GCGCTCGGCCTGACGGTCAGCGACCTGTCGGCCGATCAGCTGAAGGCGCTGAAGCTGAAGAACGGCGTGCAGGTGGACGG
CGTCGACGGTCCGGCCGCGCGCGCCGGCCTGCAGCGCGGCGACATCGTGCTGCGCGTCGGCGATACCGACATCACGAGCG
CGAAGCAGTTCGCCGAGGTGACGTCGCAGCTCGACGCGCAGAAGGCCGTCGCGGTGCTCGTGCGGCGCGGCGACAACACG
CAGTTCGTGCCGGTGCGGCCGCGCCAGAAGTAA

Upstream 100 bases:

>100_bases
TACTGGATCACCGTGCTCGGCGAAGTGCCGCCGGCAACGTTGCAGCAGTTCGCGTCTGCCATAGAATACAAGGCTTCCAA
GTAACGCTACGGCTTCCGAC

Downstream 100 bases:

>100_bases
CGCGCGATGTTCACGCTCTACGGCCGCGGCTGGTGCCATCTCTGCGACGACATGCGCGACGCGCTGGCACCGGTCGCCGC
CGAATTCGGCGTGGCGGTCG

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MMKITLRKWLAAAALSACLPLVPHTAAAAPVPAASLPDFADLVEKVGPAVVNIRTTANVPSGPRGGLPPGFDNGDMSEFF
RRFFGIPLPQAPGNPKNAPAPDNAPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTD
VAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGGPLINMQG
EVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSSVEPGGPA
DKAGVQPGDIILKFNGRAVDTASDLPRMVGDTKPGTKATVTVWRKGQARDLPITIAETPSDTTAKADPRKNAPQKPRQSN
ALGLTVSDLSADQLKALKLKNGVQVDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTSQLDAQKAVAVLVRRGDNT
QFVPVRPRQK

Sequences:

>Translated_490_residues
MMKITLRKWLAAAALSACLPLVPHTAAAAPVPAASLPDFADLVEKVGPAVVNIRTTANVPSGPRGGLPPGFDNGDMSEFF
RRFFGIPLPQAPGNPKNAPAPDNAPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTD
VAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGGPLINMQG
EVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSSVEPGGPA
DKAGVQPGDIILKFNGRAVDTASDLPRMVGDTKPGTKATVTVWRKGQARDLPITIAETPSDTTAKADPRKNAPQKPRQSN
ALGLTVSDLSADQLKALKLKNGVQVDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTSQLDAQKAVAVLVRRGDNT
QFVPVRPRQK
>Mature_490_residues
MMKITLRKWLAAAALSACLPLVPHTAAAAPVPAASLPDFADLVEKVGPAVVNIRTTANVPSGPRGGLPPGFDNGDMSEFF
RRFFGIPLPQAPGNPKNAPAPDNAPDTEQNRGVGSGFIVSADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTD
VAVVKIQASNLPVVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGGPLINMQG
EVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADSIGLPKAEGALVSSVEPGGPA
DKAGVQPGDIILKFNGRAVDTASDLPRMVGDTKPGTKATVTVWRKGQARDLPITIAETPSDTTAKADPRKNAPQKPRQSN
ALGLTVSDLSADQLKALKLKNGVQVDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTSQLDAQKAVAVLVRRGDNT
QFVPVRPRQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=355, Percent_Identity=34.9295774647887, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI22129776, Length=339, Percent_Identity=34.5132743362832, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=36.4, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.8406374501992, Blast_Score=149, Evalue=5e-36,
Organism=Escherichia coli, GI1789629, Length=492, Percent_Identity=37.3983739837398, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI1786356, Length=488, Percent_Identity=34.8360655737705, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789630, Length=294, Percent_Identity=37.0748299319728, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24646839, Length=292, Percent_Identity=37.6712328767123, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 51211; Mature: 51211

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKITLRKWLAAAALSACLPLVPHTAAAAPVPAASLPDFADLVEKVGPAVVNIRTTANVP
CEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
SGPRGGLPPGFDNGDMSEFFRRFFGIPLPQAPGNPKNAPAPDNAPDTEQNRGVGSGFIVS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEE
ADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASNLPVVAIGDSN
CCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCEEEECCCC
KVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGGPLINMQG
CEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCCCCEEEECC
EVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADS
CEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHH
IGLPKAEGALVSSVEPGGPADKAGVQPGDIILKFNGRAVDTASDLPRMVGDTKPGTKATV
CCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCEEECCHHHHHHHHCCCCCCCEEEE
TVWRKGQARDLPITIAETPSDTTAKADPRKNAPQKPRQSNALGLTVSDLSADQLKALKLK
EEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHC
NGVQVDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTSQLDAQKAVAVLVRRGDNT
CCCEEECCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCC
QFVPVRPRQK
EEEECCCCCC
>Mature Secondary Structure
MMKITLRKWLAAAALSACLPLVPHTAAAAPVPAASLPDFADLVEKVGPAVVNIRTTANVP
CEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCC
SGPRGGLPPGFDNGDMSEFFRRFFGIPLPQAPGNPKNAPAPDNAPDTEQNRGVGSGFIVS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCEEEE
ADGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDDRTDVAVVKIQASNLPVVAIGDSN
CCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCEEEECCCC
KVRVGEWVVAIGSPFGLDNTVTAGIVSSKSRNTGDYLPFIQTDVAVNPGNSGGPLINMQG
CEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEECCCCCCCCEEEECC
EVIGINSQIYSRTGGFMGISFAIPIDEAMRVADQLKATGKVTRGRIAVAIGEVTKDVADS
CEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHH
IGLPKAEGALVSSVEPGGPADKAGVQPGDIILKFNGRAVDTASDLPRMVGDTKPGTKATV
CCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCEEECCHHHHHHHHCCCCCCCEEEE
TVWRKGQARDLPITIAETPSDTTAKADPRKNAPQKPRQSNALGLTVSDLSADQLKALKLK
EEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHC
NGVQVDGVDGPAARAGLQRGDIVLRVGDTDITSAKQFAEVTSQLDAQKAVAVLVRRGDNT
CCCEEECCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCC
QFVPVRPRQK
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]