Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 161525336

GI number: 161525336

Start: 2383308

End: 2383748

Strand: Reverse

Name: acpS

Synonym: Bmul_2166

Alternate gene names: 161525336

Gene position: 2383748-2383308 (Counterclockwise)

Preceding gene: 161525337

Following gene: 161525335

Centisome position: 69.12

GC content: 69.16

Gene sequence:

>441_bases
ATGGCGATCTACGGCATCGGCACCGACATCGTGCAGGTCAGCCGCGTCGCGGCCGTGCTCGAGCGTACCGGCGGACGCTT
CGCGGAGAAGGTGCTCGGCCCCGACGAACTGCGCGTGTTCCATGCGCGCCGCGCCCGTTCAGAGGCGCGCGGCATCGCGT
TTCTCGCGACACGCTTTTCCGCGAAGGAAGCCTTCTCGAAGGCGATCGGGCTCGGCATGCATTGGCCGATGACCTGGCGC
GCGTTGCAGACGCTCAATCGACCGAGCGGCGAGCCGTACGTCGTCGCATCGGGCGAACTGGCCGACTGGCTCGCGGCGCG
CGGCATCACCGCGCGCGTGACGGTCAGCGACGAGCGCGATTACGCGGTGTCGTTCGTGATCGCCGAGACCGGCCTGCCTG
CGCCCGACGCACCCACCGCTGTTTCCCGAACCACTCCCTGA

Upstream 100 bases:

>100_bases
CGGCGGCGCGCGCTGACGATGCGGTCGTTGCGTACGACGCGCGTCGCATGCGGGCTGCCGACCGCGCACGCGACACCGCC
GCGGGCGCGAAGGAGCTGAC

Downstream 100 bases:

>100_bases
CGGACTTCCCGATTCGATGAAAACGACTCCCGGCCCGGTCATGCTCGACGTCGTCGGCACGGCCCTGTCACGCGACGATG
CGCGGCGTCTCGCGCATCCG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MAIYGIGTDIVQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWR
ALQTLNRPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVIAETGLPAPDAPTAVSRTTP

Sequences:

>Translated_146_residues
MAIYGIGTDIVQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWR
ALQTLNRPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVIAETGLPAPDAPTAVSRTTP
>Mature_145_residues
AIYGIGTDIVQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRA
LQTLNRPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVIAETGLPAPDAPTAVSRTTP

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=131, Percent_Identity=35.8778625954198, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BURM1 (A9ADD4)

Other databases:

- EMBL:   CP000868
- EMBL:   AP009385
- RefSeq:   YP_001580348.1
- RefSeq:   YP_001945555.1
- ProteinModelPortal:   A9ADD4
- SMR:   A9ADD4
- GeneID:   5767252
- GeneID:   6359869
- GenomeReviews:   AP009385_GR
- GenomeReviews:   CP000868_GR
- KEGG:   bmj:BMULJ_01075
- KEGG:   bmu:Bmul_2166
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15772; Mature: 15641

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYGIGTDIVQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFS
CEEEECCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEHHHHH
AKEAFSKAIGLGMHWPMTWRALQTLNRPSGEPYVVASGELADWLAARGITARVTVSDERD
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCEEEEEECCCCC
YAVSFVIAETGLPAPDAPTAVSRTTP
EEEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIYGIGTDIVQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFS
EEEECCHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEHHHHH
AKEAFSKAIGLGMHWPMTWRALQTLNRPSGEPYVVASGELADWLAARGITARVTVSDERD
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCEEEEEECCCCC
YAVSFVIAETGLPAPDAPTAVSRTTP
EEEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA