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The map label for this gene is nagZ [H]

Identifier: 161525335

GI number: 161525335

Start: 2382263

End: 2383291

Strand: Reverse

Name: nagZ [H]

Synonym: Bmul_2165

Alternate gene names: 161525335

Gene position: 2383291-2382263 (Counterclockwise)

Preceding gene: 161525336

Following gene: 161525331

Centisome position: 69.11

GC content: 68.9

Gene sequence:

>1029_bases
ATGAAAACGACTCCCGGCCCGGTCATGCTCGACGTCGTCGGCACGGCCCTGTCACGCGACGATGCGCGGCGTCTCGCGCA
TCCGAACACCGGCGGCGTGATCCTGTTCGCGCGGCACTTTCAGAACCGCGCGCAACTGACCGCGCTGACCGATGCGATCC
GCGCAGTGCGCGACGATATCCTGATCGCGGTCGATCACGAAGGCGGGCGCGTGCAGCGCTTCCGCACCGACGGCTTCACG
GTGCTGCCGGCGATGCGCCGCCTCGGCGAGCTATGGGATCGCGACGTGCTGCTCGCGACGAAAGTGGCGACCGCGGTCGG
CTACATCCTTGCCGCCGAGCTGCGCGCGTGCGGGATCGACATGAGCTTTACGCCGGTGCTCGACCTCGACTACGGTCAGT
CGCAGGTGATCGGCGATCGGGCGTTCCATCGCGATCCGCGCGTCGTCACGCTGCTCGCGAAGAGCCTCAATCACGGGCTT
GCGCTCGCCGGCATGGCGAACTGCGGCAAGCATTTCCCCGGCCACGGCTTCGCGGAAGCGGACTCGCACGTCGCGCTGCC
GACCGACGACCGTCCGCTCGAGACGATCCTCGCACAGGACGTCGCGCCGTACGACTGGCTCGGCCTGTCGTTGTCGGCCG
TGATTCCCGCGCACGTGATCTATACGCAGGTCGACGCGCGCCCGGCCGGCTTCTCGCGCGTCTGGCTGCAGGACATCCTG
CGCGGCCGGCTCGGCTTTACCGGCGCGATCTTCAGCGACGATCTGTCGATGGAAGCCGCGCGCGAGGGCGGCACGCTGAC
GCAGGCCGCCGACGCGGCGCTCGCCGCCGGCTGCGACATGGTGCTCGTGTGCAATCAGCCGGAAGCGGCCGAAGTGGTCC
TGAACGAGCTGAAGGCCGAGCGCAATGCCGATTCCGCACGGCGCATCAAGCGGATGCGCGCACGCGGCAAGGCGCTCAAG
TGGGACAAGCTGATCGAGCAGCCCGAGTATCGGCGCGCGCAGGCGCTGCTGGCCGACGCGCTCCGATAA

Upstream 100 bases:

>100_bases
GATTACGCGGTGTCGTTCGTGATCGCCGAGACCGGCCTGCCTGCGCCCGACGCACCCACCGCTGTTTCCCGAACCACTCC
CTGACGGACTTCCCGATTCG

Downstream 100 bases:

>100_bases
GGGCAGGGGAGCGCGGTGCGCGGGCCGCCGCCGCGCGCCGGTCGCATCAAGCAAAAAGCCGCGCGTTTGCGCGGCTTTTC
GCTCAAAGCGCTCTTTCAAT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKTTPGPVMLDVVGTALSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVRDDILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGIDMSFTPVLDLDYGQSQVIGDRAFHRDPRVVTLLAKSLNHGL
ALAGMANCGKHFPGHGFAEADSHVALPTDDRPLETILAQDVAPYDWLGLSLSAVIPAHVIYTQVDARPAGFSRVWLQDIL
RGRLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPEAAEVVLNELKAERNADSARRIKRMRARGKALK
WDKLIEQPEYRRAQALLADALR

Sequences:

>Translated_342_residues
MKTTPGPVMLDVVGTALSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVRDDILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGIDMSFTPVLDLDYGQSQVIGDRAFHRDPRVVTLLAKSLNHGL
ALAGMANCGKHFPGHGFAEADSHVALPTDDRPLETILAQDVAPYDWLGLSLSAVIPAHVIYTQVDARPAGFSRVWLQDIL
RGRLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPEAAEVVLNELKAERNADSARRIKRMRARGKALK
WDKLIEQPEYRRAQALLADALR
>Mature_342_residues
MKTTPGPVMLDVVGTALSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVRDDILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGIDMSFTPVLDLDYGQSQVIGDRAFHRDPRVVTLLAKSLNHGL
ALAGMANCGKHFPGHGFAEADSHVALPTDDRPLETILAQDVAPYDWLGLSLSAVIPAHVIYTQVDARPAGFSRVWLQDIL
RGRLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPEAAEVVLNELKAERNADSARRIKRMRARGKALK
WDKLIEQPEYRRAQALLADALR

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=314, Percent_Identity=45.859872611465, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37275; Mature: 37275

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTPGPVMLDVVGTALSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVRDDI
CCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCE
LIAVDHEGGRVQRFRTDGFTVLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGID
EEEEECCCCEEEEEECCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLDYGQSQVIGDRAFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGFAEA
CCCCEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
DSHVALPTDDRPLETILAQDVAPYDWLGLSLSAVIPAHVIYTQVDARPAGFSRVWLQDIL
CCEEECCCCCCHHHHHHHHCCCCCHHHCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
RGRLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPEAAEVVLNELKAE
HHHCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
RNADSARRIKRMRARGKALKWDKLIEQPEYRRAQALLADALR
CCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTTPGPVMLDVVGTALSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVRDDI
CCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCE
LIAVDHEGGRVQRFRTDGFTVLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGID
EEEEECCCCEEEEEECCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLDYGQSQVIGDRAFHRDPRVVTLLAKSLNHGLALAGMANCGKHFPGHGFAEA
CCCCEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCC
DSHVALPTDDRPLETILAQDVAPYDWLGLSLSAVIPAHVIYTQVDARPAGFSRVWLQDIL
CCEEECCCCCCHHHHHHHHCCCCCHHHCCHHHHHHHHHHEEEECCCCCCCHHHHHHHHHH
RGRLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPEAAEVVLNELKAE
HHHCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
RNADSARRIKRMRARGKALKWDKLIEQPEYRRAQALLADALR
CCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]