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The map label for this gene is efp [H]

Identifier: 161525333

GI number: 161525333

Start: 2379865

End: 2380422

Strand: Direct

Name: efp [H]

Synonym: Bmul_2163

Alternate gene names: 161525333

Gene position: 2379865-2380422 (Clockwise)

Preceding gene: 161525332

Following gene: 161525334

Centisome position: 69.01

GC content: 59.32

Gene sequence:

>558_bases
ATGAAGACCGCACAGGAACTCCGCGTAGGCAACGTCGTGCAGATCGGCAGCGACGCTTGGGTCATCTCGAAGACGGAATA
CAACAAGTCGGGCCGTAACGCCGCCGTCGTCAAGCTGAAGATGAAGAACCTGCTGACGAACGCAGGCCAGGAATCGGTCT
ACAAGGCCGACGACAAGTTCGACGTCGTCATGCTCGACCGCAAGGAAGTGACGTACTCGTACTTCGCCGACCCGATGTAC
GTGTTCATGGACGCCGACTACAACCAGTACGAAGTCGAAGCCGAAATGATGGGCGACGCGCTGAACTACCTCGAAGACGG
CATGGCGTGCGAAGTCGTGTTCTACAACGAGAAGGCGATCTCGGTCGAACTGCCGACGATCCTCGTTCGCGAGATCACGT
ACACGGAACCGGCCGTCAAGGGCGACACGTCGTCGGGCAAGGTGCTGAAGAACGCGAAGCTCGCGACGGGCTTCGAACTG
CAGGTGCCGCTGTTCTGCAACACCGGCGACAAGATCGAAATCGACACGCGCACGCACGAGTACCGCAGCCGCGCGTAA

Upstream 100 bases:

>100_bases
CGCTCGCTTTTGGCGCCCACGGAACCTTCCCGCTTGCGCTGTCAGCCGTTGTGCAACGCTCAGGCACCTATTTATTTGAT
TTGATCAGGACAGTTTTTTT

Downstream 100 bases:

>100_bases
CCGCTCTCGATGCCGCATTGAACAAAGCGCCCTTCGGGGCGCTTTTTGTTTGTCCGTTCGCAACAGCGGCGTGCCGGACG
CGGGCCGCGCGCCCGACGTA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKTAQELRVGNVVQIGSDAWVISKTEYNKSGRNAAVVKLKMKNLLTNAGQESVYKADDKFDVVMLDRKEVTYSYFADPMY
VFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAISVELPTILVREITYTEPAVKGDTSSGKVLKNAKLATGFEL
QVPLFCNTGDKIEIDTRTHEYRSRA

Sequences:

>Translated_185_residues
MKTAQELRVGNVVQIGSDAWVISKTEYNKSGRNAAVVKLKMKNLLTNAGQESVYKADDKFDVVMLDRKEVTYSYFADPMY
VFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAISVELPTILVREITYTEPAVKGDTSSGKVLKNAKLATGFEL
QVPLFCNTGDKIEIDTRTHEYRSRA
>Mature_185_residues
MKTAQELRVGNVVQIGSDAWVISKTEYNKSGRNAAVVKLKMKNLLTNAGQESVYKADDKFDVVMLDRKEVTYSYFADPMY
VFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAISVELPTILVREITYTEPAVKGDTSSGKVLKNAKLATGFEL
QVPLFCNTGDKIEIDTRTHEYRSRA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=31.8681318681319, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=31.0526315789474, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20875; Mature: 20875

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAQELRVGNVVQIGSDAWVISKTEYNKSGRNAAVVKLKMKNLLTNAGQESVYKADDKF
CCCHHHCCCCCEEEECCCEEEEEECCCCCCCCCEEEEEEEEHHHHHCCCCCCEEECCCCE
DVVMLDRKEVTYSYFADPMYVFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAI
EEEEEECCCCEEEECCCEEEEEEECCCCEEEEHHHHHHHHHHHHHCCCEEEEEEECCEEE
SVELPTILVREITYTEPAVKGDTSSGKVLKNAKLATGFELQVPLFCNTGDKIEIDTRTHE
EEECCEEEEEEEECCCCCCCCCCCCCCEEECCEECCCEEEEEEEEECCCCEEEEECCCCH
YRSRA
HHCCC
>Mature Secondary Structure
MKTAQELRVGNVVQIGSDAWVISKTEYNKSGRNAAVVKLKMKNLLTNAGQESVYKADDKF
CCCHHHCCCCCEEEECCCEEEEEECCCCCCCCCEEEEEEEEHHHHHCCCCCCEEECCCCE
DVVMLDRKEVTYSYFADPMYVFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAI
EEEEEECCCCEEEECCCEEEEEEECCCCEEEEHHHHHHHHHHHHHCCCEEEEEEECCEEE
SVELPTILVREITYTEPAVKGDTSSGKVLKNAKLATGFELQVPLFCNTGDKIEIDTRTHE
EEECCEEEEEEEECCCCCCCCCCCCCCEEECCEECCCEEEEEEEEECCCCEEEEECCCCH
YRSRA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA