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The map label for this gene is dnaQ [H]

Identifier: 161525206

GI number: 161525206

Start: 2231982

End: 2232716

Strand: Direct

Name: dnaQ [H]

Synonym: Bmul_2036

Alternate gene names: 161525206

Gene position: 2231982-2232716 (Clockwise)

Preceding gene: 161525205

Following gene: 161525208

Centisome position: 64.72

GC content: 66.94

Gene sequence:

>735_bases
ATGCGCCAGATCATTCTCGATACCGAAACCACCGGCCTGAACGCCCGCTCGGGCGACCGCATCATCGAAATCGGCTGCGT
CGAGCTGCTGAACCGGCGGCTCACCGGCAACAACCTGCACTTCTACGTGAATCCGGAGCGCGACAGCGATCCGGGCGCAC
TGGCCGTGCACGGCCTCACGACCGAGTTCCTCAGCGACAAGCCGAAGTTCGCGGAAATCGCGCATCAGATTCTCGACTTC
GTGAAAGGCGCGGAGCTGATCATCCACAATGCGCCGTTCGACCTCGGCTTTCTCGACGCCGAATTCGCGCTGCTCGGGCT
GCCGCCGTTCAGCGAGCACTGCGCGGGCGTCATCGACACGCTGGTGCAGGCCAAGCAGATGTTCCCCGGCAAGCGCAACT
CGCTCGACGCGCTGTGCGACCGCTTCGGCATCAGCAACGCGCACCGCACGCTGCACGGCGCGCTGCTCGACTCGGAGCTG
CTCGCCGAGGTCTATCTCGCGATGACGCGCGGCCAGGACAGCCTCGTCATCGACATGCTCGACGACGACGCGGGCGGTGC
CGGCGCCGCCAACGGCCAGCGCGTGTCGCTTGCGGCGCTGGACCTGCCGGTGCTCGCCGCCACGGCCGAAGAGCTCGCCG
AGCATCAGGCGCAGCTCGACGATCTCGACAAGTCGGTCAAGGGTGCATGCGTGTGGCGCCAGGCGGACGAAGCCGACACG
GCCGAAGCCGCATGA

Upstream 100 bases:

>100_bases
ATCCCGAAAACGAACGCGCGGACGCGCTCGCGAATCGCGGCGTCGCGTCGCTCGCGGCCTGAGCGACGGCCGCTTTTTTG
CCTTTCCCGATTTATCCGAC

Downstream 100 bases:

>100_bases
AGCGGCGGCCGCCGCGCGCGCGCCGCCTGCTCATCCGCGCGGCTGCAGCGCGATGACAGCCATGCCGGCCAGCGCGAGCG
CCGCGCCGGCCGCGTCCCAG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRQIILDTETTGLNARSGDRIIEIGCVELLNRRLTGNNLHFYVNPERDSDPGALAVHGLTTEFLSDKPKFAEIAHQILDF
VKGAELIIHNAPFDLGFLDAEFALLGLPPFSEHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSEL
LAEVYLAMTRGQDSLVIDMLDDDAGGAGAANGQRVSLAALDLPVLAATAEELAEHQAQLDDLDKSVKGACVWRQADEADT
AEAA

Sequences:

>Translated_244_residues
MRQIILDTETTGLNARSGDRIIEIGCVELLNRRLTGNNLHFYVNPERDSDPGALAVHGLTTEFLSDKPKFAEIAHQILDF
VKGAELIIHNAPFDLGFLDAEFALLGLPPFSEHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSEL
LAEVYLAMTRGQDSLVIDMLDDDAGGAGAANGQRVSLAALDLPVLAATAEELAEHQAQLDDLDKSVKGACVWRQADEADT
AEAA
>Mature_244_residues
MRQIILDTETTGLNARSGDRIIEIGCVELLNRRLTGNNLHFYVNPERDSDPGALAVHGLTTEFLSDKPKFAEIAHQILDF
VKGAELIIHNAPFDLGFLDAEFALLGLPPFSEHCAGVIDTLVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSEL
LAEVYLAMTRGQDSLVIDMLDDDAGGAGAANGQRVSLAALDLPVLAATAEELAEHQAQLDDLDKSVKGACVWRQADEADT
AEAA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=54.6218487394958, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26286; Mature: 26286

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIILDTETTGLNARSGDRIIEIGCVELLNRRLTGNNLHFYVNPERDSDPGALAVHGLT
CCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCH
TEFLSDKPKFAEIAHQILDFVKGAELIIHNAPFDLGFLDAEFALLGLPPFSEHCAGVIDT
HHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCEEEEECCCHHHHHHHHHHH
LVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSELLAEVYLAMTRGQDSLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
DDDAGGAGAANGQRVSLAALDLPVLAATAEELAEHQAQLDDLDKSVKGACVWRQADEADT
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
AEAA
CCCC
>Mature Secondary Structure
MRQIILDTETTGLNARSGDRIIEIGCVELLNRRLTGNNLHFYVNPERDSDPGALAVHGLT
CCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCH
TEFLSDKPKFAEIAHQILDFVKGAELIIHNAPFDLGFLDAEFALLGLPPFSEHCAGVIDT
HHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCEEEEECCCHHHHHHHHHHH
LVQAKQMFPGKRNSLDALCDRFGISNAHRTLHGALLDSELLAEVYLAMTRGQDSLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
DDDAGGAGAANGQRVSLAALDLPVLAATAEELAEHQAQLDDLDKSVKGACVWRQADEADT
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
AEAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]