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The map label for this gene is yegE [C]

Identifier: 161525114

GI number: 161525114

Start: 2128782

End: 2131199

Strand: Reverse

Name: yegE [C]

Synonym: Bmul_1942

Alternate gene names: 161525114

Gene position: 2131199-2128782 (Counterclockwise)

Preceding gene: 161525115

Following gene: 161525113

Centisome position: 61.8

GC content: 67.54

Gene sequence:

>2418_bases
ATGGAAAACATTTCGAGGCTCCAGCGTCAACGCAGCGCGTTTCATGTCTGGCCCTGGAGTCCCGCGCTCGGCATCCTGCC
GATCGTGGTCGTGATGGTCGCGCTGGCGGGCTTCGTCGCCGTCAGCCTGATCATCATCATGTCGTTGCGCGTGTACGTCG
GCGGCGAAAGCAACTGGTCCAAAGCGCAGAAGGACGCGATCATCCTGTTGAACCGCTACGGCGAGACCGGCGACGAGCGT
CTGTTCGACGCGTACGCGAGCACCGACCGCACGCTGCGCTTTCTGACGGTCGCGCGCGCGGCGATGACGGCCGTGCCGCC
CGACCACGCGACCGCGCGCGGCGCGATGATCGCGGCCGGCATCAATCCGCTCGATGCGGCCGCGGTCGTCTGGTTCTATC
CGGTGCTGGCGAGCTTCGCGCGGCTCGACCCCGCGCTGCAGTACTGGCAGGCGGCCGACCGGCAGCTCGACGCGTTGCGC
ACCGTCGCGCATGCGCTGCGCGATGCGGTGAAGGCGCACGACGGGCCGCGCACGCGTGCGCTCGCGCAGCGCGTATGGGA
GATCAACTCGCGGATCGAGCCGCTGCCGAAGCGGTTCTCCAGCGAGCTGAGCGCGGAATTCCGCTCGGCCGTCATTCAGC
TGTTCCTGTCGTACCTCGCCGCATCGTTGCTGATCGTCTTTCTCGGCGTGCGCTGGGCGGGCCGCGCGCAGCATCAGCAG
CGCTCGATCCAGAGCGAGCTCGATCGCAGCCAGGCGCTCGCCGAAGCCGCGCTGCGTTCGGTTGCCGACGCGATCGTCAC
GGTCGGTCTGACGAGCGGCATCGAGACCGTCAATCCGGCCGCCGAGCAGTTGCTCGGCACATCGGCGCGCGACTGCATCG
GCAAGCCCGTGAACGACGTGCTGGCGCTGATCGATCCGTCGACCGGCATGTCGATCAACCTGCTGCCGTCGCTCAGCAAT
AGCGGCGACGCGACGCTGACGCGCGACCTCGAACTGCTCCGCGCCGATGCGCCCGCGGTCGCCGTGCGGGCGTCGCTGTC
GCGGATGGACAATGCGCCGGGCCGCTGCGTCGGCTATGTGCTGATCCTGCGCGACATGACGCGCGAATATCAGCTGATCG
AGCGGCTGACCTGGCAGGCCTCGCACGATGCGCTGACGGGCCTGATCAACCGCACCGCGTTCGAGCGGCGCGTCGGCGAG
GCGCTGAACGCATGCGCGGCGACGGTGCTGCTCGTGCTCGATCTCGACGGCTTCAAGGAGGTCAACGACGTGTGCGGCCA
CGCGGCCGGCGACGCGCTGCTGCGCGAAGTCACCGCGGTGTTCCAGCGTTGCCTCGGCGCCGACGACGCGTTCGGCCGCC
TCGGCGGCGACGAATTCGGGATCCTGCTGACCGCGACGGGCGGCCCGCTGCCGGACGGCGGCAAGGCCGAGCAGCTTCGC
GCGAGCCTCGAGGCGTACACGTTCTGCTGGGACGGCGAGCGCTTCAAGCTGAGCGTCAGCATCGGGATGCTGAATCTCGA
CTGCCGGCCCGAAAGCGTCGAGAAGGCGATGCAGCTCGCGGACGTCGCCTGCTACGTCGCGAAGGATCGCGGCCGCAATC
GCGTCCACGTCGCCGAGCCGCGCGACATGAGCGCGAGCCGGCAGGCGTATCACCTGGAGTGGAGCCGCCGCGTGAAGGCC
GCGCTCGAGTCGAATACGTTCCAGCTGTATGCGCAGCCGATCGTGCCGATCCAGCCGGCGCTCGCCGCGCAGCAGCGCAT
CGAGATCCTGCTGCGCATCCCCGACGCCGACGGCAAGCTCGTGTCGCCGGTATTCCTGCCGGCTGCCGAGCGCTACGGGC
ACATGACGATGATCGACCGCTGGGTCGTGCGCACCGTCGTGCGGCGACTCGCGCAGCTCGAACGGCGCAGCGACTTCGAA
TGCAACGTGAACCTGTCCGCGATGTCGATCACGAACGAAGGCTTCGTCGAGTTCGTGAAGCGCGAGCTGACGACGTCGGG
CGTCGATCCGTCGCAGCTGTGTTTCGAGATCACCGAAACGAGCGCCGTGCGCAATCTCGAAGTCGCGTCGCGTTTCATGC
ACGAGCTGCGCGATCTCGGCTGCCGGTTCGCGCTCGACGATTTCGGCGCCGGCATGTCGTCGTTTTCCTATCTGAGCAAG
CTGCCGATCGATTATCTGAAGATCGACGGCGGCCTCGTATCGCGCATGACGTCGGATTGCGTGAAGCGCGGCATCGTCTG
CGCGATCAACGATATCGCGCACCTGCTGCAGTACCGGACCGTTGCGGAGCACGTCGAGGACGAGGAGACGGCCGAGATGC
TTCGCTCGCTGGGCGTCGACTACTGCCAGGGCTACTACTTCAGCCGTCCCGCGCGATGGCAGGCCGGGGAGCCTGTACAA
CAAGGAGAAGTGGAATGA

Upstream 100 bases:

>100_bases
GCTGTAGCGCAAGCAGTCGAAGTCAGCGGCGCAGCCGCGCCGCAAGCAGCGAACACTCCGGGCCGGGAGTGTCGAATAAG
CATAAGAACAGTGAATCGGT

Downstream 100 bases:

>100_bases
AAGTGCCGTTCGAGAGAACCGGTGAGCTGATGGATCTGGGCAGCTACCCGGCCTGGTTGCGCGACGTGGTCGGCGCGACG
GCGGAATTGAAGGAGCGGGT

Product: PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 805; Mature: 805

Protein sequence:

>805_residues
MENISRLQRQRSAFHVWPWSPALGILPIVVVMVALAGFVAVSLIIIMSLRVYVGGESNWSKAQKDAIILLNRYGETGDER
LFDAYASTDRTLRFLTVARAAMTAVPPDHATARGAMIAAGINPLDAAAVVWFYPVLASFARLDPALQYWQAADRQLDALR
TVAHALRDAVKAHDGPRTRALAQRVWEINSRIEPLPKRFSSELSAEFRSAVIQLFLSYLAASLLIVFLGVRWAGRAQHQQ
RSIQSELDRSQALAEAALRSVADAIVTVGLTSGIETVNPAAEQLLGTSARDCIGKPVNDVLALIDPSTGMSINLLPSLSN
SGDATLTRDLELLRADAPAVAVRASLSRMDNAPGRCVGYVLILRDMTREYQLIERLTWQASHDALTGLINRTAFERRVGE
ALNACAATVLLVLDLDGFKEVNDVCGHAAGDALLREVTAVFQRCLGADDAFGRLGGDEFGILLTATGGPLPDGGKAEQLR
ASLEAYTFCWDGERFKLSVSIGMLNLDCRPESVEKAMQLADVACYVAKDRGRNRVHVAEPRDMSASRQAYHLEWSRRVKA
ALESNTFQLYAQPIVPIQPALAAQQRIEILLRIPDADGKLVSPVFLPAAERYGHMTMIDRWVVRTVVRRLAQLERRSDFE
CNVNLSAMSITNEGFVEFVKRELTTSGVDPSQLCFEITETSAVRNLEVASRFMHELRDLGCRFALDDFGAGMSSFSYLSK
LPIDYLKIDGGLVSRMTSDCVKRGIVCAINDIAHLLQYRTVAEHVEDEETAEMLRSLGVDYCQGYYFSRPARWQAGEPVQ
QGEVE

Sequences:

>Translated_805_residues
MENISRLQRQRSAFHVWPWSPALGILPIVVVMVALAGFVAVSLIIIMSLRVYVGGESNWSKAQKDAIILLNRYGETGDER
LFDAYASTDRTLRFLTVARAAMTAVPPDHATARGAMIAAGINPLDAAAVVWFYPVLASFARLDPALQYWQAADRQLDALR
TVAHALRDAVKAHDGPRTRALAQRVWEINSRIEPLPKRFSSELSAEFRSAVIQLFLSYLAASLLIVFLGVRWAGRAQHQQ
RSIQSELDRSQALAEAALRSVADAIVTVGLTSGIETVNPAAEQLLGTSARDCIGKPVNDVLALIDPSTGMSINLLPSLSN
SGDATLTRDLELLRADAPAVAVRASLSRMDNAPGRCVGYVLILRDMTREYQLIERLTWQASHDALTGLINRTAFERRVGE
ALNACAATVLLVLDLDGFKEVNDVCGHAAGDALLREVTAVFQRCLGADDAFGRLGGDEFGILLTATGGPLPDGGKAEQLR
ASLEAYTFCWDGERFKLSVSIGMLNLDCRPESVEKAMQLADVACYVAKDRGRNRVHVAEPRDMSASRQAYHLEWSRRVKA
ALESNTFQLYAQPIVPIQPALAAQQRIEILLRIPDADGKLVSPVFLPAAERYGHMTMIDRWVVRTVVRRLAQLERRSDFE
CNVNLSAMSITNEGFVEFVKRELTTSGVDPSQLCFEITETSAVRNLEVASRFMHELRDLGCRFALDDFGAGMSSFSYLSK
LPIDYLKIDGGLVSRMTSDCVKRGIVCAINDIAHLLQYRTVAEHVEDEETAEMLRSLGVDYCQGYYFSRPARWQAGEPVQ
QGEVE
>Mature_805_residues
MENISRLQRQRSAFHVWPWSPALGILPIVVVMVALAGFVAVSLIIIMSLRVYVGGESNWSKAQKDAIILLNRYGETGDER
LFDAYASTDRTLRFLTVARAAMTAVPPDHATARGAMIAAGINPLDAAAVVWFYPVLASFARLDPALQYWQAADRQLDALR
TVAHALRDAVKAHDGPRTRALAQRVWEINSRIEPLPKRFSSELSAEFRSAVIQLFLSYLAASLLIVFLGVRWAGRAQHQQ
RSIQSELDRSQALAEAALRSVADAIVTVGLTSGIETVNPAAEQLLGTSARDCIGKPVNDVLALIDPSTGMSINLLPSLSN
SGDATLTRDLELLRADAPAVAVRASLSRMDNAPGRCVGYVLILRDMTREYQLIERLTWQASHDALTGLINRTAFERRVGE
ALNACAATVLLVLDLDGFKEVNDVCGHAAGDALLREVTAVFQRCLGADDAFGRLGGDEFGILLTATGGPLPDGGKAEQLR
ASLEAYTFCWDGERFKLSVSIGMLNLDCRPESVEKAMQLADVACYVAKDRGRNRVHVAEPRDMSASRQAYHLEWSRRVKA
ALESNTFQLYAQPIVPIQPALAAQQRIEILLRIPDADGKLVSPVFLPAAERYGHMTMIDRWVVRTVVRRLAQLERRSDFE
CNVNLSAMSITNEGFVEFVKRELTTSGVDPSQLCFEITETSAVRNLEVASRFMHELRDLGCRFALDDFGAGMSSFSYLSK
LPIDYLKIDGGLVSRMTSDCVKRGIVCAINDIAHLLQYRTVAEHVEDEETAEMLRSLGVDYCQGYYFSRPARWQAGEPVQ
QGEVE

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=541, Percent_Identity=27.1719038817006, Blast_Score=193, Evalue=5e-50,
Organism=Escherichia coli, GI1787541, Length=579, Percent_Identity=27.6338514680484, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1788849, Length=238, Percent_Identity=36.5546218487395, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=29.3577981651376, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=34.2857142857143, Blast_Score=130, Evalue=5e-31,
Organism=Escherichia coli, GI226510982, Length=443, Percent_Identity=25.2821670428894, Blast_Score=129, Evalue=9e-31,
Organism=Escherichia coli, GI87081980, Length=257, Percent_Identity=33.4630350194552, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI87082096, Length=442, Percent_Identity=24.6606334841629, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=38.75, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788502, Length=237, Percent_Identity=28.6919831223629, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=29.8319327731092, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081845, Length=236, Percent_Identity=30.9322033898305, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786507, Length=245, Percent_Identity=27.7551020408163, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1787055, Length=250, Percent_Identity=29.6, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=190, Percent_Identity=32.6315789473684, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=36.3128491620112, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1787262, Length=179, Percent_Identity=32.4022346368715, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787802, Length=171, Percent_Identity=29.8245614035088, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=34.1772151898734, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788085, Length=181, Percent_Identity=28.1767955801105, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI87081977, Length=171, Percent_Identity=28.6549707602339, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 88689; Mature: 88689

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENISRLQRQRSAFHVWPWSPALGILPIVVVMVALAGFVAVSLIIIMSLRVYVGGESNWS
CCHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHH
KAQKDAIILLNRYGETGDERLFDAYASTDRTLRFLTVARAAMTAVPPDHATARGAMIAAG
HHCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEC
INPLDAAAVVWFYPVLASFARLDPALQYWQAADRQLDALRTVAHALRDAVKAHDGPRTRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LAQRVWEINSRIEPLPKRFSSELSAEFRSAVIQLFLSYLAASLLIVFLGVRWAGRAQHQQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RSIQSELDRSQALAEAALRSVADAIVTVGLTSGIETVNPAAEQLLGTSARDCIGKPVNDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHCCCCHHHH
LALIDPSTGMSINLLPSLSNSGDATLTRDLELLRADAPAVAVRASLSRMDNAPGRCVGYV
HHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
LILRDMTREYQLIERLTWQASHDALTGLINRTAFERRVGEALNACAATVLLVLDLDGFKE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VNDVCGHAAGDALLREVTAVFQRCLGADDAFGRLGGDEFGILLTATGGPLPDGGKAEQLR
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCHHHHH
ASLEAYTFCWDGERFKLSVSIGMLNLDCRPESVEKAMQLADVACYVAKDRGRNRVHVAEP
HHHHHHEEEECCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
RDMSASRQAYHLEWSRRVKAALESNTFQLYAQPIVPIQPALAAQQRIEILLRIPDADGKL
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCCE
VSPVFLPAAERYGHMTMIDRWVVRTVVRRLAQLERRSDFECNVNLSAMSITNEGFVEFVK
ECHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHHHHHHH
RELTTSGVDPSQLCFEITETSAVRNLEVASRFMHELRDLGCRFALDDFGAGMSSFSYLSK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCHHHHHHHHH
LPIDYLKIDGGLVSRMTSDCVKRGIVCAINDIAHLLQYRTVAEHVEDEETAEMLRSLGVD
CCCHHEEECCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHH
YCQGYYFSRPARWQAGEPVQQGEVE
HHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MENISRLQRQRSAFHVWPWSPALGILPIVVVMVALAGFVAVSLIIIMSLRVYVGGESNWS
CCHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHH
KAQKDAIILLNRYGETGDERLFDAYASTDRTLRFLTVARAAMTAVPPDHATARGAMIAAG
HHCCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEC
INPLDAAAVVWFYPVLASFARLDPALQYWQAADRQLDALRTVAHALRDAVKAHDGPRTRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LAQRVWEINSRIEPLPKRFSSELSAEFRSAVIQLFLSYLAASLLIVFLGVRWAGRAQHQQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
RSIQSELDRSQALAEAALRSVADAIVTVGLTSGIETVNPAAEQLLGTSARDCIGKPVNDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHCCCCHHHH
LALIDPSTGMSINLLPSLSNSGDATLTRDLELLRADAPAVAVRASLSRMDNAPGRCVGYV
HHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
LILRDMTREYQLIERLTWQASHDALTGLINRTAFERRVGEALNACAATVLLVLDLDGFKE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VNDVCGHAAGDALLREVTAVFQRCLGADDAFGRLGGDEFGILLTATGGPLPDGGKAEQLR
HHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCHHHHH
ASLEAYTFCWDGERFKLSVSIGMLNLDCRPESVEKAMQLADVACYVAKDRGRNRVHVAEP
HHHHHHEEEECCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
RDMSASRQAYHLEWSRRVKAALESNTFQLYAQPIVPIQPALAAQQRIEILLRIPDADGKL
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHEEEECCCCCCCE
VSPVFLPAAERYGHMTMIDRWVVRTVVRRLAQLERRSDFECNVNLSAMSITNEGFVEFVK
ECHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHHHHHHH
RELTTSGVDPSQLCFEITETSAVRNLEVASRFMHELRDLGCRFALDDFGAGMSSFSYLSK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCHHHHHHHHH
LPIDYLKIDGGLVSRMTSDCVKRGIVCAINDIAHLLQYRTVAEHVEDEETAEMLRSLGVD
CCCHHEEECCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHH
YCQGYYFSRPARWQAGEPVQQGEVE
HHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]