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The map label for this gene is mdtP [H]

Identifier: 161524923

GI number: 161524923

Start: 1935719

End: 1937215

Strand: Direct

Name: mdtP [H]

Synonym: Bmul_1750

Alternate gene names: 161524923

Gene position: 1935719-1937215 (Clockwise)

Preceding gene: 161524922

Following gene: 161524924

Centisome position: 56.13

GC content: 68.94

Gene sequence:

>1497_bases
ATGAAATCCTCCCCGTTGTCCGTGCGTGCCGGGTCGCGCCGCACCGCCGTTGCCGTTGCGGTCGCCGCACTGGCACTGGC
GGGCTGCGCGAACTACATCGGCATCAAGAGCGACAAGCAGATCGCCCCCGCGTCGCAGTTCGAAACCGCGCAGAGCCTTC
CGGCCCAGGGCGGCCACTGGCCGTCGCTCGACTGGGCGAGCCAGTTCGGCGATCCGCAGCTGCCGAAGCTGATCGACGAG
GCGCTCGCCGGCAATCCGTCGATCGCGCAGGCGCAGGCGCGCATCGCGAAGGCGTCGTCGTATATCGAATCGTCGCGCTC
GAACCTGCTGCCGAAGGCCGAAGCGAGCTACTCGTGGACGCGCGAGCTCTATTCGGCGAACGGCCTCTTCCCGCCGCCGT
ACGGCGGCCAGTGGTACAGCGAGAACAACGTGCTCGCCAGCGCATCGTGGGAGCTCGACCTGTGGGGCAAGAACCGCGAG
CGCCTGCGCACGGCCGTGTCGCAGGAAAAGGCCGCGGAAGCCGACATGCAGCAGGCGCGCATCACGCTCGCCTCGTCGGT
CGCGCGCACCTACAACTCGCTCGCGCAGCTGTACGCGCTGCGCGACATCGCGCAGCGCGAGATCGCCAACCGCGAGTCGG
TCGGCAAGATCACCGACGGCCGCGTGTCGGCCGGCCTCGACACGAACGTCGAACGCCAGACCGCACGCGGCAACATCGCG
ACGACGCAGGCGTCGCTGTCCGATCTCGACGGTCAGATCACGACCGTGCGCTACCAGCTCGCCGCACTGCTCGGCAAAGG
GCCGGACCGCGGGCTGCAGATCGCCGCGCCGGTGCTGAACCCGGCCGGCGACGTCGCGCTACCCGACAACCTGCCCGCCG
ACCTCGTATCGCGCCGCCCCGACATCGTCGCCGCGCGCTGGCAGGTCGAAGCGGCAATGCACGACGTGAAGGAAGCGAAG
GCCGAGTTCTTCCCGGACGTGAACCTCGCGGCCGGTTTCGGTTTCGATGCGTTCGGCTGGGGCAAATTCCTGAACTTCAC
GAGCCGCCAGGCGCAGTTCGGCCCGGCGATCCATCTGCCGATCTTCGACGCCGGCGCGCTGCGCGCGCAGCTCAAGGGCC
GCTACGCGGACTTCGATCTGTCGGTCGCGAACTACAACCAGACGCTGATCAGCGCGCTGAACGACGTGGCGACGCAAGTT
GCCGCGATCCGTGCGATCGATCGCCAGATGGGCGACGCGCAGCGCGCGCTCGACGCGTCGACGCGCGCATACGATCTCGC
GGTGATTCGCTACAAGGCCGGCCTGTCGCCGCAGCTGCAGGTGCTGACCGCGGACAGCAACCGGCTCGCCTCGGAGCAGA
CCGTGACGAATCTGAAGATGCGCCGTCGCGACATGCAGCTCGCGCTGATCAAGGCGCTCGGCGGCGGCTTCGATGCGACC
GGCACCGCGCTCGCGGCGCCCGAGACCGCGAAACAGACCCGACAGGCCGCCAACTGA

Upstream 100 bases:

>100_bases
CAGCGTCGCGCAATAGTTGCCATAACAATTACTTTTGACAGATTAATGTAAGGAAATCCTTGCAGTGTCCATCATTCATT
CCGAGTCAGGGATCAGCGCG

Downstream 100 bases:

>100_bases
TCCGGCGCCGCCCTACCAAGACACTCGAAATAACGGACGGAGAAAATCGCCATGAGCGACCCTCAACAAAACGCCGCCAG
CGCCCAGCCGCAGAACAACG

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MKSSPLSVRAGSRRTAVAVAVAALALAGCANYIGIKSDKQIAPASQFETAQSLPAQGGHWPSLDWASQFGDPQLPKLIDE
ALAGNPSIAQAQARIAKASSYIESSRSNLLPKAEASYSWTRELYSANGLFPPPYGGQWYSENNVLASASWELDLWGKNRE
RLRTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREIANRESVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPAGDVALPDNLPADLVSRRPDIVAARWQVEAAMHDVKEAK
AEFFPDVNLAAGFGFDAFGWGKFLNFTSRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
AAIRAIDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTALAAPETAKQTRQAAN

Sequences:

>Translated_498_residues
MKSSPLSVRAGSRRTAVAVAVAALALAGCANYIGIKSDKQIAPASQFETAQSLPAQGGHWPSLDWASQFGDPQLPKLIDE
ALAGNPSIAQAQARIAKASSYIESSRSNLLPKAEASYSWTRELYSANGLFPPPYGGQWYSENNVLASASWELDLWGKNRE
RLRTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREIANRESVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPAGDVALPDNLPADLVSRRPDIVAARWQVEAAMHDVKEAK
AEFFPDVNLAAGFGFDAFGWGKFLNFTSRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
AAIRAIDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTALAAPETAKQTRQAAN
>Mature_498_residues
MKSSPLSVRAGSRRTAVAVAVAALALAGCANYIGIKSDKQIAPASQFETAQSLPAQGGHWPSLDWASQFGDPQLPKLIDE
ALAGNPSIAQAQARIAKASSYIESSRSNLLPKAEASYSWTRELYSANGLFPPPYGGQWYSENNVLASASWELDLWGKNRE
RLRTAVSQEKAAEADMQQARITLASSVARTYNSLAQLYALRDIAQREIANRESVGKITDGRVSAGLDTNVERQTARGNIA
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPAGDVALPDNLPADLVSRRPDIVAARWQVEAAMHDVKEAK
AEFFPDVNLAAGFGFDAFGWGKFLNFTSRQAQFGPAIHLPIFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQV
AAIRAIDRQMGDAQRALDASTRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
GTALAAPETAKQTRQAAN

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=482, Percent_Identity=31.1203319502075, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1786785, Length=465, Percent_Identity=27.3118279569892, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53474; Mature: 53474

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSPLSVRAGSRRTAVAVAVAALALAGCANYIGIKSDKQIAPASQFETAQSLPAQGGHW
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCC
PSLDWASQFGDPQLPKLIDEALAGNPSIAQAQARIAKASSYIESSRSNLLPKAEASYSWT
CCCCHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RELYSANGLFPPPYGGQWYSENNVLASASWELDLWGKNRERLRTAVSQEKAAEADMQQAR
HHHHHCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ITLASSVARTYNSLAQLYALRDIAQREIANRESVGKITDGRVSAGLDTNVERQTARGNIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEECCCCCCCHHHHCCCCCE
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPAGDVALPDNLPADLVSRRP
ECHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCC
DIVAARWQVEAAMHDVKEAKAEFFPDVNLAAGFGFDAFGWGKFLNFTSRQAQFGPAIHLP
CEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEE
IFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQVAAIRAIDRQMGDAQRALDAS
ECCCHHHHHHHCCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
CCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTALAAPETAKQTRQAAN
CCEECCCHHHHHHHHCCC
>Mature Secondary Structure
MKSSPLSVRAGSRRTAVAVAVAALALAGCANYIGIKSDKQIAPASQFETAQSLPAQGGHW
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCC
PSLDWASQFGDPQLPKLIDEALAGNPSIAQAQARIAKASSYIESSRSNLLPKAEASYSWT
CCCCHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
RELYSANGLFPPPYGGQWYSENNVLASASWELDLWGKNRERLRTAVSQEKAAEADMQQAR
HHHHHCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ITLASSVARTYNSLAQLYALRDIAQREIANRESVGKITDGRVSAGLDTNVERQTARGNIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEECCCCCCCHHHHCCCCCE
TTQASLSDLDGQITTVRYQLAALLGKGPDRGLQIAAPVLNPAGDVALPDNLPADLVSRRP
ECHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCC
DIVAARWQVEAAMHDVKEAKAEFFPDVNLAAGFGFDAFGWGKFLNFTSRQAQFGPAIHLP
CEEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCEEEEE
IFDAGALRAQLKGRYADFDLSVANYNQTLISALNDVATQVAAIRAIDRQMGDAQRALDAS
ECCCHHHHHHHCCCCCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRAYDLAVIRYKAGLSPQLQVLTADSNRLASEQTVTNLKMRRRDMQLALIKALGGGFDAT
CCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GTALAAPETAKQTRQAAN
CCEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]