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The map label for this gene is ppiD [H]

Identifier: 161524527

GI number: 161524527

Start: 1490720

End: 1492654

Strand: Direct

Name: ppiD [H]

Synonym: Bmul_1354

Alternate gene names: 161524527

Gene position: 1490720-1492654 (Clockwise)

Preceding gene: 161524526

Following gene: 161524529

Centisome position: 43.23

GC content: 65.94

Gene sequence:

>1935_bases
ATGCTCGATTTCTTCCGTAATCACCAGCGCCTGATGATGGCGCTCCTGCTCCTGATCGTATTGCCGGGGCTGGGTTTCGT
CGGGATCCAAGGTTTCCGCGGCTTCTTCGACGAAAGCGCGAACGTCGCGGCGGTCAACGGGCACAAGATCACGCGCGTCG
AATTCGACGGCGCGTTTCGTCAGCAGATCGACCAGGCGCGTCAGGCGCTCGGCGCTCAGTTCGACATCAAGGCGTTCGAT
ACGCCGGAACACCGCAAGCAGGTGCTCGACGGCCTGATCCAGCAGCGCGTGCTCGCCGATGAAACGCAGCGTCTGCATCT
GACGGCCTCGGATAACGCCGTGCGCGAAGCGCTGCTGAGCGATCCGATGATCGCGTCGCTGAAGAAGCCCGACGGCTCGA
TCGACGTCGAGCGCTATGCGCAACTGATGTCGTTCCAGGGCATGACGCCCGAGCAGTATCAGGAGCGCGTGCGTTACAGC
CTCGCGCTGCAGCAGATTCCGGCGAGCATCGTGTCGAGCGCGTTTACGCCGAAGAGCCTCGCGCAGCGGCTGTCGGAACT
CGCCGCGCAGCAGCGTGAAGTGCAGGCGCTCGTGCTGAAGACGAGCGACTATGCATCGAAGGTCCAGCCGACCGACGCAC
AGCTCGCCGCGTACTACGACGCGCACAAGCAGCAGTTCGCGACGCCCGAGACGGCGACGATCGAGTATCTCGTCTATTCG
CCGGCCGCGGCCGCCGCGAGCGCGCAGCCGACCGACGCGGACATCAAGAAGTTCTACGACGACAACCCGACGCACTTCCG
CACCGAAGCGCAGGTTCGCGTGAGCCACATCTTCATCGCTGCGGCGAGCGATGCGAGCGCCGCGGACAAGGCGGCCGCGA
AGGCCAAGGCCGAGCAGCTGCTCGCCGACGTGAAGGCGCACCCGGACCAGTTCGCGCAGATCGCCGAGAAGAACTCGCAG
GACGCGCCGTCGGCGGCGAAGGGCGGCGATCTCGGCTTCATCACGCGCGGCTCGACCGCGGGCGGCAAGGCATTCGACGA
TGCGGCGTTCGCGCTGAAGCAAGGCGAGATCAGCGGCGTCGTGCAGTCCGATCTCGGCTTCCACATCCTGAAGGCGACCG
AGGTGAAGCCGTCGATCGTCAAGCCGTTCGCGGAAGTGAAGGACGAAATCGCCGCGACGCTGAAGCAGCAATACGCGGCG
AAGGCGTTCTCGGACAACGCGGAAGGCTTCACGTCGACCGTCTACGAGAAGGCGAAGAGCCTGCAGCCGGCCGCCGACAA
GTACAAGCTGACGATCCAGACGGCGACCGTCACGCCGACGCCCAATCCGCAACTGCCGGCCACGAGCCCGCTGAACAACG
CGAAGTTCCTCGCGGCGGTGTTCGCGAACGACTCGGTGAAGGCGCACAACAACACGCAGGCGATCGACGTCGGCAACAAC
ACGCTGATCTCGGCGCGCGTGACCGACTACAAGCCGGCCGCCGTGCCCGCGCTCGACGCGATCAAGGACGCCGTGCGCCA
GAAGGTCGTCGCCGAGCAGGCTGCCGAACTCGCGAAGAAGGACGGCGCGGCGAAGCTCGCGGAACTGCAGAAGTCGAAGT
CGACCGAAGGTTTCGCGGCCGCGCAGAAGATCTCGCGCACGCAATCGCAGGGCCTGAGCCCGGCCGCGCTGAGCGCCGTC
TACAAGGTCGATCCGAAGACGCTGCCCGCCTATGTCGGCGTCGATCTCGGTGCGGACGGCTATGCGATCTATCGCGTGAA
CGCGGTGATCCCCGGTTCGGCCGTCGATCCGCAGCAGCTGGCGGCCGCGCAGCAGCAGACGGCGCAGGTCGAGGCGCAGA
GCGAGGGCGAAGCGTATCTCGCCGCGCTGCGCGATCGCTCGAAGGTCAAGCTGTACGGTTCGACCGCGAGCCAGTCGCAG
GGCAACGACGACTGA

Upstream 100 bases:

>100_bases
TCCGGCGGCGCCCCGCGGCGGCGCGCCGTCCTGCCGGTTCGCCTTTTTTCCCGCCCACTGTTGTAATATCGGGCGTTTTG
TCCAATACACCCCGTCACGC

Downstream 100 bases:

>100_bases
GCGTCGACTGAGTGATTTCGCGCGCAACCTGATGCGCGTCGTGCGCCGCCCGGCGGCAGCGCGGCGCGATCCGCATTCCG
ATCCCTGTCCGGCATTGCGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDESANVAAVNGHKITRVEFDGAFRQQIDQARQALGAQFDIKAFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVREALLSDPMIASLKKPDGSIDVERYAQLMSFQGMTPEQYQERVRYS
LALQQIPASIVSSAFTPKSLAQRLSELAAQQREVQALVLKTSDYASKVQPTDAQLAAYYDAHKQQFATPETATIEYLVYS
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAASDASAADKAAAKAKAEQLLADVKAHPDQFAQIAEKNSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGEISGVVQSDLGFHILKATEVKPSIVKPFAEVKDEIAATLKQQYAA
KAFSDNAEGFTSTVYEKAKSLQPAADKYKLTIQTATVTPTPNPQLPATSPLNNAKFLAAVFANDSVKAHNNTQAIDVGNN
TLISARVTDYKPAAVPALDAIKDAVRQKVVAEQAAELAKKDGAAKLAELQKSKSTEGFAAAQKISRTQSQGLSPAALSAV
YKVDPKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQTAQVEAQSEGEAYLAALRDRSKVKLYGSTASQSQ
GNDD

Sequences:

>Translated_644_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDESANVAAVNGHKITRVEFDGAFRQQIDQARQALGAQFDIKAFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVREALLSDPMIASLKKPDGSIDVERYAQLMSFQGMTPEQYQERVRYS
LALQQIPASIVSSAFTPKSLAQRLSELAAQQREVQALVLKTSDYASKVQPTDAQLAAYYDAHKQQFATPETATIEYLVYS
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAASDASAADKAAAKAKAEQLLADVKAHPDQFAQIAEKNSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGEISGVVQSDLGFHILKATEVKPSIVKPFAEVKDEIAATLKQQYAA
KAFSDNAEGFTSTVYEKAKSLQPAADKYKLTIQTATVTPTPNPQLPATSPLNNAKFLAAVFANDSVKAHNNTQAIDVGNN
TLISARVTDYKPAAVPALDAIKDAVRQKVVAEQAAELAKKDGAAKLAELQKSKSTEGFAAAQKISRTQSQGLSPAALSAV
YKVDPKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQTAQVEAQSEGEAYLAALRDRSKVKLYGSTASQSQ
GNDD
>Mature_644_residues
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDESANVAAVNGHKITRVEFDGAFRQQIDQARQALGAQFDIKAFD
TPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVREALLSDPMIASLKKPDGSIDVERYAQLMSFQGMTPEQYQERVRYS
LALQQIPASIVSSAFTPKSLAQRLSELAAQQREVQALVLKTSDYASKVQPTDAQLAAYYDAHKQQFATPETATIEYLVYS
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAASDASAADKAAAKAKAEQLLADVKAHPDQFAQIAEKNSQ
DAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGEISGVVQSDLGFHILKATEVKPSIVKPFAEVKDEIAATLKQQYAA
KAFSDNAEGFTSTVYEKAKSLQPAADKYKLTIQTATVTPTPNPQLPATSPLNNAKFLAAVFANDSVKAHNNTQAIDVGNN
TLISARVTDYKPAAVPALDAIKDAVRQKVVAEQAAELAKKDGAAKLAELQKSKSTEGFAAAQKISRTQSQGLSPAALSAV
YKVDPKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQLAAAQQQTAQVEAQSEGEAYLAALRDRSKVKLYGSTASQSQ
GNDD

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=652, Percent_Identity=27.9141104294479, Blast_Score=190, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69065; Mature: 69065

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDESANVAAVNGHKITRVEFDGAFR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCHHH
QQIDQARQALGAQFDIKAFDTPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVREALLS
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHC
DPMIASLKKPDGSIDVERYAQLMSFQGMTPEQYQERVRYSLALQQIPASIVSSAFTPKSL
CCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AQRLSELAAQQREVQALVLKTSDYASKVQPTDAQLAAYYDAHKQQFATPETATIEYLVYS
HHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEC
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAASDASAADKAAAKAKAEQL
CHHHHCCCCCCCHHHHHHCCCCCCEEECHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHH
LADVKAHPDQFAQIAEKNSQDAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGEISGV
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHH
VQSDLGFHILKATEVKPSIVKPFAEVKDEIAATLKQQYAAKAFSDNAEGFTSTVYEKAKS
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LQPAADKYKLTIQTATVTPTPNPQLPATSPLNNAKFLAAVFANDSVKAHNNTQAIDVGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCEECCCCCEEEECCCC
TLISARVTDYKPAAVPALDAIKDAVRQKVVAEQAAELAKKDGAAKLAELQKSKSTEGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
AQKISRTQSQGLSPAALSAVYKVDPKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCHHHH
AAAQQQTAQVEAQSEGEAYLAALRDRSKVKLYGSTASQSQGNDD
HHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLDFFRNHQRLMMALLLLIVLPGLGFVGIQGFRGFFDESANVAAVNGHKITRVEFDGAFR
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCHHH
QQIDQARQALGAQFDIKAFDTPEHRKQVLDGLIQQRVLADETQRLHLTASDNAVREALLS
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHC
DPMIASLKKPDGSIDVERYAQLMSFQGMTPEQYQERVRYSLALQQIPASIVSSAFTPKSL
CCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AQRLSELAAQQREVQALVLKTSDYASKVQPTDAQLAAYYDAHKQQFATPETATIEYLVYS
HHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEC
PAAAAASAQPTDADIKKFYDDNPTHFRTEAQVRVSHIFIAAASDASAADKAAAKAKAEQL
CHHHHCCCCCCCHHHHHHCCCCCCEEECHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHH
LADVKAHPDQFAQIAEKNSQDAPSAAKGGDLGFITRGSTAGGKAFDDAAFALKQGEISGV
HHHHHCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHH
VQSDLGFHILKATEVKPSIVKPFAEVKDEIAATLKQQYAAKAFSDNAEGFTSTVYEKAKS
HHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
LQPAADKYKLTIQTATVTPTPNPQLPATSPLNNAKFLAAVFANDSVKAHNNTQAIDVGNN
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCEECCCCCEEEECCCC
TLISARVTDYKPAAVPALDAIKDAVRQKVVAEQAAELAKKDGAAKLAELQKSKSTEGFAA
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHH
AQKISRTQSQGLSPAALSAVYKVDPKTLPAYVGVDLGADGYAIYRVNAVIPGSAVDPQQL
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCHHHH
AAAQQQTAQVEAQSEGEAYLAALRDRSKVKLYGSTASQSQGNDD
HHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]