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The map label for this gene is benK [H]

Identifier: 161524526

GI number: 161524526

Start: 1489125

End: 1490471

Strand: Direct

Name: benK [H]

Synonym: Bmul_1353

Alternate gene names: 161524526

Gene position: 1489125-1490471 (Clockwise)

Preceding gene: 161524525

Following gene: 161524527

Centisome position: 43.18

GC content: 65.78

Gene sequence:

>1347_bases
ATGCGAAATATCGACGTATGCCAATTGTCCGACGGCGCGCGGTTTGGCCGGTTTCATGCCGGCATCCTGTTCTGGTGTGC
GCTGATCATCATCTTTGACGGCTATGACCTCGCGGTGGTCGGCATCGCGCTGCCGTCGATCATGGCCGAGATGAAGGTCG
GTCCGACCGGCGCCGGCTTGATGGTCAGCTCGGCGCTGTTCGGCATGATGCTGGGCGCCGTGTTTCTCGGCACGATCGCC
GATCGCATCGGCCGCGTGCGCGCGATCGTCATCTGCATTCTGCTGTTCAGTATTTTTACCGCGGCGGCGGGCGTCGCCCA
CGGGCCCGTCACGTTCTGCATCGCGCGCTTTCTCGCCGGCCTCGGCATCGGCGGCGTAATGCCCAACGTCGTCGCGCAGA
TGACCGAATTCTCGCCGCGCCGCATCCGCAGCACGCTCGTCACGCTGATGTTCAGCGGCTACTCGGTGGGCGGCATGCTG
GCCGCGCTGGTCGGCAAGGCGATGATCGCCCGTTACGGCTGGCAGTCGGTGTTCATCGCGGCGGGTTTGCCGGTGTTGCT
CGTGCCCGCGATTCTCGCGTACATGCCCGAGTCGATGAGCTTTCTGATCCGCAAGGGGCGCACCGATACCGTCGGGCACG
TGCTGTCGCGTATCGCGCCCGGCTATCGACCGCAACAGGGCGACCGCTTTTCGATCGCGGGCCAGGAGAAGGGTGACGCG
CCGGGCATTCGCAGCCTGTTTGCCGATGGACGCGGCTTCAGCACCGTCATGCTGTGGGTCGCCTTTTTCATGTGCCTGTT
CATGGTCTATGCGTTGAGTTCGTGGCTGACGAAGCTGATGGCCGGCGCGGGCTACAGCCTCGGCTCGGCATTGACCTTCG
TGCTCGTGCTGAATTTCGGCGCGATGATCGGCGCGATCGGCGGCGGCTGGCTCGCCGACCGCTTCAACATGAAGCACGTG
CTGGTCGCGATGTATGGGCTCGCGGCCGTGTCGATCGGCCTGCTCGGCGTGAAGGTGCCCGAGCCCGTGCTGTTCGTGCT
GGTCGGCCTGGCCGGCGCATCGACGATCGGCACGCAGATCGTCACCTATGCATTCGCCGGGCAGTTCTACCCGATGGCCG
CCAAATCGACCGGGATCGGCTGGGCGTCCGGCGTCGGGCGCAGCGGCGCCATTCTCGCGCCGATCGTGATCGGCTTTCTG
GTCAGTCAGGCGCTGCCGCTTCAGCAGAACTTCCTGGCCATCGCCGTGCCGGGGCTGATCGCGATGGTCGCCGTCGGCCT
GATGCGCCCGCTCGAGCCGGTGCATGCGCAACGAAGCGTCGAAGCGGCGCAGGCCGACGTCGCGTAA

Upstream 100 bases:

>100_bases
CGTAAGCGCGACGGGGCCGCACAACAACAAGCAATACAACTGGACGCGTGCCGGATCGTCGCATTCGGCACGAGAACCTC
AGGTTTAAATGGAGACCCGA

Downstream 100 bases:

>100_bases
GGCGGTGGTCGGGCGGGGCCGCGCGGCGATGCGTCGCGGCGGCGGCCCGCCCGTGCGGCATTTTCGCCGTACTCGGGACA
AGGGACATATCGCGGCGAGC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRNIDVCQLSDGARFGRFHAGILFWCALIIIFDGYDLAVVGIALPSIMAEMKVGPTGAGLMVSSALFGMMLGAVFLGTIA
DRIGRVRAIVICILLFSIFTAAAGVAHGPVTFCIARFLAGLGIGGVMPNVVAQMTEFSPRRIRSTLVTLMFSGYSVGGML
AALVGKAMIARYGWQSVFIAAGLPVLLVPAILAYMPESMSFLIRKGRTDTVGHVLSRIAPGYRPQQGDRFSIAGQEKGDA
PGIRSLFADGRGFSTVMLWVAFFMCLFMVYALSSWLTKLMAGAGYSLGSALTFVLVLNFGAMIGAIGGGWLADRFNMKHV
LVAMYGLAAVSIGLLGVKVPEPVLFVLVGLAGASTIGTQIVTYAFAGQFYPMAAKSTGIGWASGVGRSGAILAPIVIGFL
VSQALPLQQNFLAIAVPGLIAMVAVGLMRPLEPVHAQRSVEAAQADVA

Sequences:

>Translated_448_residues
MRNIDVCQLSDGARFGRFHAGILFWCALIIIFDGYDLAVVGIALPSIMAEMKVGPTGAGLMVSSALFGMMLGAVFLGTIA
DRIGRVRAIVICILLFSIFTAAAGVAHGPVTFCIARFLAGLGIGGVMPNVVAQMTEFSPRRIRSTLVTLMFSGYSVGGML
AALVGKAMIARYGWQSVFIAAGLPVLLVPAILAYMPESMSFLIRKGRTDTVGHVLSRIAPGYRPQQGDRFSIAGQEKGDA
PGIRSLFADGRGFSTVMLWVAFFMCLFMVYALSSWLTKLMAGAGYSLGSALTFVLVLNFGAMIGAIGGGWLADRFNMKHV
LVAMYGLAAVSIGLLGVKVPEPVLFVLVGLAGASTIGTQIVTYAFAGQFYPMAAKSTGIGWASGVGRSGAILAPIVIGFL
VSQALPLQQNFLAIAVPGLIAMVAVGLMRPLEPVHAQRSVEAAQADVA
>Mature_448_residues
MRNIDVCQLSDGARFGRFHAGILFWCALIIIFDGYDLAVVGIALPSIMAEMKVGPTGAGLMVSSALFGMMLGAVFLGTIA
DRIGRVRAIVICILLFSIFTAAAGVAHGPVTFCIARFLAGLGIGGVMPNVVAQMTEFSPRRIRSTLVTLMFSGYSVGGML
AALVGKAMIARYGWQSVFIAAGLPVLLVPAILAYMPESMSFLIRKGRTDTVGHVLSRIAPGYRPQQGDRFSIAGQEKGDA
PGIRSLFADGRGFSTVMLWVAFFMCLFMVYALSSWLTKLMAGAGYSLGSALTFVLVLNFGAMIGAIGGGWLADRFNMKHV
LVAMYGLAAVSIGLLGVKVPEPVLFVLVGLAGASTIGTQIVTYAFAGQFYPMAAKSTGIGWASGVGRSGAILAPIVIGFL
VSQALPLQQNFLAIAVPGLIAMVAVGLMRPLEPVHAQRSVEAAQADVA

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=417, Percent_Identity=23.9808153477218, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI7662270, Length=221, Percent_Identity=29.8642533936652, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI73695465, Length=216, Percent_Identity=31.0185185185185, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI216548223, Length=216, Percent_Identity=30.0925925925926, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI262399383, Length=164, Percent_Identity=30.4878048780488, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI213021148, Length=209, Percent_Identity=23.9234449760766, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI24497476, Length=382, Percent_Identity=24.6073298429319, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI20070188, Length=382, Percent_Identity=24.6073298429319, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI8923870, Length=388, Percent_Identity=25.5154639175258, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081723, Length=374, Percent_Identity=31.283422459893, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786229, Length=390, Percent_Identity=24.3589743589744, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082159, Length=403, Percent_Identity=28.0397022332506, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87082231, Length=412, Percent_Identity=24.0291262135922, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082404, Length=372, Percent_Identity=24.1935483870968, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788074, Length=357, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI32564663, Length=415, Percent_Identity=23.855421686747, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19922874, Length=430, Percent_Identity=23.953488372093, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24640198, Length=219, Percent_Identity=26.9406392694064, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640196, Length=219, Percent_Identity=26.9406392694064, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24640200, Length=219, Percent_Identity=26.9406392694064, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47003; Mature: 47003

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00120 LIPASE_SER ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]