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The map label for this gene is atzB [H]

Identifier: 161524486

GI number: 161524486

Start: 1442099

End: 1443511

Strand: Direct

Name: atzB [H]

Synonym: Bmul_1313

Alternate gene names: 161524486

Gene position: 1442099-1443511 (Clockwise)

Preceding gene: 161524483

Following gene: 161524489

Centisome position: 41.82

GC content: 69.07

Gene sequence:

>1413_bases
ATGAACCTCGAGCAGTACGCCGGCGCACGCGCGCCGCAATCCTCCCCATCCCGCCCGACCACCTTGCTGGTCAAGCACGC
CGACGTGCTCGTGACCATGGACGACACGCGGCGCGAACTGCGCGACGCGGGGCTCTACATCGAAGACAACCGGATCGTCG
CCGTTGGCCCGAGCGCCGAACTGCCCGATACCGCGGACGAGGTGCTCGATCTGCGCGGGCATCTCGTGATTCCGGGGCTC
GTGAACACGCACCATCACATGTATCAGAGCCTCACGCGCGCGGTGCCGGCCGCGCAGAACGCCGAGCTGTTCGGCTGGCT
CACGAACCTGTACCGGATCTGGGCGAACCTGACGTCCGAGATGATCGAAGTCTCGACGCTGACCGCGATGGCCGAGCTGC
TGCAGTCGGGCTGCACGACGTCGAGCGACCATCTGTATATCTATCCGAACGGCAGCCGGCTCGACGACAGCATCGCGGCC
GCGCAGCGGATCGGGATGCGCTTTCACGCGAGCCGCGGTGCGATGAGCGTCGGCCAGCGCGACGGCGGGCTGCCGCCCGA
TTCGGTCGTCGAGCGCGAGCCCGACATCCTGCGCGACGCGCAGCGGCTGATCGAGACCTATCACGACGAAGGCCGCTACG
CGATGCTGCGCGTCGTCGTCGCGCCGTGTTCGCCGTTTTCGGTGAGCCGCGGGCTGATGCGCGACGCCGCTTTGCTCGCG
CGCGAGTACGGCGTGTCGCTGCACACGCACCTCGCCGAGAACGTCAACGACATCGCGTACAGCCGCGAGAAGTTCGGGAT
GACGCCGGCCGAATACGCGGAAGATCTCGGCTGGGTCGGCCACGACGTCTGGCATGCGCACTGCGTGCAGCTCGACGACG
CGGGCATCGGCCTGTTCGCGCGCACGGGCACCGGCGTCGCGCACTGTCCGTGCTCGAACATGCGGCTCGCGTCCGGTATC
GCGCCGGTGAAGAAGATGCGGCTCGCGGGTGTGCCGGTCGGGCTTGGCGTCGACGGCTCGGCATCGAACGACGGCGCGCA
GATGGTCGCCGAAGTGCGGCAGGCGCTGCTGCTGCAGCGGGTCGGCTTCGGCCCCGATGCGATGACCGCGCGCGAAGCGC
TCGAGATCGCGACGCTCGGCGGCGCGAAGGTGCTGAACCGCGACGACATCGGCGCGCTGAAGCCGGGCATGGCCGCCGAC
TTCGCGGCGTTCGACCTGCGTCAGCCGCTGTTCGCGGGCGCGCTGCACGATCCGGTCGCGGCGCTCGTGTTCTGCGCGCC
GTCGCAGACGGCCTATACGGTCGTAAACGGGAAGGTGGTCGTGCGCGAAGGTCGGCTCGCGACGCTCGATCTGCCGCCCG
TGATCGAACGTCACAACGCGCTCGCGAAGGCGCTCGTCGAAGCGTCGCGCTAG

Upstream 100 bases:

>100_bases
TCGAACGGACGCAGGCACCGGAGCGTGCCGCGACGCAGCGTTCGAACGGCTTTGTGAGCGCCCCCGCAAGCGGTCGGGGG
CAGACCGACGCGGAGAACGC

Downstream 100 bases:

>100_bases
TCGGCGCGGCGGCGGTCTTGAACACCGCCGCGACCGCCGCACGACGCACGACGCGCGGCGCGCGGCGCATGCACGCCCGA
GCTGCGCGACGTTTGGCGCG

Product: hydroxydechloroatrazine ethylaminohydrolase

Products: NA

Alternate protein names: Hydroxyatrazine hydrolase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNLEQYAGARAPQSSPSRPTTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWANLTSEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIAA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAALLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAKALVEASR

Sequences:

>Translated_470_residues
MNLEQYAGARAPQSSPSRPTTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWANLTSEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIAA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAALLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAKALVEASR
>Mature_470_residues
MNLEQYAGARAPQSSPSRPTTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPDTADEVLDLRGHLVIPGL
VNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWANLTSEMIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIAA
AQRIGMRFHASRGAMSVGQRDGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAALLA
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFARTGTGVAHCPCSNMRLASGI
APVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAAD
FAAFDLRQPLFAGALHDPVAALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAKALVEASR

Specific function: Catalyzes the deamination reaction of hydroxyatrazine to N-isopropylammelide (dihydroxy-isopropyl-atrazine). The enzyme is also capable of catalyzing some dechlorinating reactions [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATZ/TRZ family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=382, Percent_Identity=24.0837696335079, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789249, Length=440, Percent_Identity=29.5454545454545, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI87082177, Length=425, Percent_Identity=25.1764705882353, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540282, Length=404, Percent_Identity=23.5148514851485, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319963, Length=345, Percent_Identity=25.7971014492754, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24643849, Length=357, Percent_Identity=24.0896358543417, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.99.3 [H]

Molecular weight: Translated: 50679; Mature: 50679

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEQYAGARAPQSSPSRPTTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAE
CCCHHHCCCCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHCCCEEECCEEEEECCCCC
LPDTADEVLDLRGHLVIPGLVNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWANLTSE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIAAAQRIGMRFHASRGAMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEECCCCCHHCCCC
DGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAALLA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHEEEEECCCCCEEEE
RTGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAADFAAFDLRQPLFAGALHDPVA
CCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHH
ALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAKALVEASR
HHEEECCCCCEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLEQYAGARAPQSSPSRPTTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAE
CCCHHHCCCCCCCCCCCCCCEEEEEECEEEEEECHHHHHHHHCCCEEECCEEEEECCCCC
LPDTADEVLDLRGHLVIPGLVNTHHHMYQSLTRAVPAAQNAELFGWLTNLYRIWANLTSE
CCCCHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MIEVSTLTAMAELLQSGCTTSSDHLYIYPNGSRLDDSIAAAQRIGMRFHASRGAMSVGQR
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHEECCCCCHHCCCC
DGGLPPDSVVEREPDILRDAQRLIETYHDEGRYAMLRVVVAPCSPFSVSRGLMRDAALLA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
REYGVSLHTHLAENVNDIAYSREKFGMTPAEYAEDLGWVGHDVWHAHCVQLDDAGIGLFA
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHEEEEECCCCCEEEE
RTGTGVAHCPCSNMRLASGIAPVKKMRLAGVPVGLGVDGSASNDGAQMVAEVRQALLLQR
ECCCCEEECCCCCCCHHHCCCHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHH
VGFGPDAMTAREALEIATLGGAKVLNRDDIGALKPGMAADFAAFDLRQPLFAGALHDPVA
CCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHH
ALVFCAPSQTAYTVVNGKVVVREGRLATLDLPPVIERHNALAKALVEASR
HHEEECCCCCEEEEECCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9055410 [H]