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The map label for this gene is mco [H]

Identifier: 161523953

GI number: 161523953

Start: 847520

End: 849121

Strand: Direct

Name: mco [H]

Synonym: Bmul_0773

Alternate gene names: 161523953

Gene position: 847520-849121 (Clockwise)

Preceding gene: 161523951

Following gene: 161523954

Centisome position: 24.58

GC content: 70.91

Gene sequence:

>1602_bases
ATGATTCGAAGAACCTTTCTGTCGCGCGCGATCGGGGTCGCGGCGGCATCGCTCGTCGCACGCGGTGCATGGGCGCAACA
TGCGGGACATGCCGGTATGGCGGGCATGGACGACATGCGCGACACGCCGGGAATGGGCGGTATGTCCGGGCACGGGCAGC
ACGGTAACCGGCCCGCGCCTGCGGCGCTCGCGGCAGCCGACGCGCTGCCGGCCGGCGCGCCGCTGGCCGCATTGCGCACG
CTCGCCAACGAAAGTCGCGAGCCGGGCACGTTCCGCGCGACGCTGATCGCGCAGCCGGTCGCGCGGCCGCTGCTGCGCGG
TGCGCGCCCGACGACGTTCTGGCAGTTCGGCGCGGGCGCCGACGGCCCCGTCGTCGGTCCGTTGATCGACGTGCGCGAGG
GCGATACGGTCGAGATCCGGTTCGAGAACAAGCTGCCGCAACCATCGACGATTCACTGGCACGGCCTGCCGGTGCCGCCC
GACCAGGACGGCAATCCGTCCGATGCCGTTGCGCCGGGCGCGTCGCGCGTCTACCGCTTCACGCTGCCGAAGGGCAGCGC
GGGTACGTACTGGTATCACCCGCATCCGCACATGATGACGGCCGAGCAGGTGTTCCGCGGGCTCGCGGGGCCGTTCGTCG
TGCGTGCGGCCGACGATCCGCTCGCGGGCTGGCCCGAGCGCCACCTGTTCGTGTCCGATCTGAAGCTCGCGCGCGACGGG
ACGATTCCGCCGAACGACATGATGGACTGGATGAACGGTCGCGAAGGGCAGTTCGTGCTCGTCAACGGTGCGCGCCGGCC
GCGCATCGAGGTCGCCGGCGACGAACGCTGGCGCGTCTGGAACGCGTGCAGCGCGCGCTACCTGCGCGTTGCGTTCGACG
ATGGCCGCGCGTTCGAGCATGTCGGCACCGACGGCGGCCTGTTCGGCGCGCCGCGTCGCGTCACGTCGCTGTTGCTCGCA
CCGGGCGAGCGCGCGGAGATGCTCGTTCGGGCCGGCGACCGCGCGTCGCGCGCGGTGCTGCAGGCAGCCGAGTACGACCG
CGGCAAGATGGCGATGTCGCACGACGACGGCCACGGCAGCCTGCCGCCCGATCCCGCACGCGCGCTGGCCGACGTCGTGT
TTGCGCCGGCCGCGCCGCGCGGGTTGCCCGCGACGCTGCGCACGGTGCCGCCGCTCGGCGAGCCCGTCGCGCACAAGGAG
GTCGCGTTCGGCGAAGAGATGGACATGGACGCGATGATGAAGGCAGGCGCGCATGGCCGGCCGGCGGGCATGCGTTTCAC
GATCAACGGCGACACCTATGCGCCGGGGCGCGTCACGCTGACGAGCCGCCGCGGCGACGTCGAACGCTGGACGATACGTA
ACGCCACCGACATGGATCATCCGTTCCATCTGCACGGCACGCAGTTCCAGGTGATCGAGCGCGCGACGGAAGGCGCGCGC
ACGGCCGAGCCGTTCCGCGCATGGCGCGACACCGTGAACGTCCGCAGCGGCGAGACGGTGACGATCCTGACGACGCAGGA
TATGGCCGGCGAACGCATGTTCCACTGCCACATCCTCGAACACGAAGACCTCGGCATGATGGGTACGCTGAAGGTCGTCT
GA

Upstream 100 bases:

>100_bases
GCGGTTATGATGGCGCGGGGCACGGCTTCGCATCGTGCCCGCGGGATGCGGCCCGTCCGCGTGGCGCCGCTGCCGCCGCA
CGAATAACGAGGAACGATTG

Downstream 100 bases:

>100_bases
CGTATCGGTCGTCCGGGTGTCGTCGGCACCCGGCGTTCGCCGCTGGCGGGAAAGCAGGCCGCGCATCGTTGTCGATGCGC
GGCTTTTTCTTTCTCTGGCG

Product: multicopper oxidase type 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MIRRTFLSRAIGVAAASLVARGAWAQHAGHAGMAGMDDMRDTPGMGGMSGHGQHGNRPAPAALAAADALPAGAPLAALRT
LANESREPGTFRATLIAQPVARPLLRGARPTTFWQFGAGADGPVVGPLIDVREGDTVEIRFENKLPQPSTIHWHGLPVPP
DQDGNPSDAVAPGASRVYRFTLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDG
TIPPNDMMDWMNGREGQFVLVNGARRPRIEVAGDERWRVWNACSARYLRVAFDDGRAFEHVGTDGGLFGAPRRVTSLLLA
PGERAEMLVRAGDRASRAVLQAAEYDRGKMAMSHDDGHGSLPPDPARALADVVFAPAAPRGLPATLRTVPPLGEPVAHKE
VAFGEEMDMDAMMKAGAHGRPAGMRFTINGDTYAPGRVTLTSRRGDVERWTIRNATDMDHPFHLHGTQFQVIERATEGAR
TAEPFRAWRDTVNVRSGETVTILTTQDMAGERMFHCHILEHEDLGMMGTLKVV

Sequences:

>Translated_533_residues
MIRRTFLSRAIGVAAASLVARGAWAQHAGHAGMAGMDDMRDTPGMGGMSGHGQHGNRPAPAALAAADALPAGAPLAALRT
LANESREPGTFRATLIAQPVARPLLRGARPTTFWQFGAGADGPVVGPLIDVREGDTVEIRFENKLPQPSTIHWHGLPVPP
DQDGNPSDAVAPGASRVYRFTLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDG
TIPPNDMMDWMNGREGQFVLVNGARRPRIEVAGDERWRVWNACSARYLRVAFDDGRAFEHVGTDGGLFGAPRRVTSLLLA
PGERAEMLVRAGDRASRAVLQAAEYDRGKMAMSHDDGHGSLPPDPARALADVVFAPAAPRGLPATLRTVPPLGEPVAHKE
VAFGEEMDMDAMMKAGAHGRPAGMRFTINGDTYAPGRVTLTSRRGDVERWTIRNATDMDHPFHLHGTQFQVIERATEGAR
TAEPFRAWRDTVNVRSGETVTILTTQDMAGERMFHCHILEHEDLGMMGTLKVV
>Mature_533_residues
MIRRTFLSRAIGVAAASLVARGAWAQHAGHAGMAGMDDMRDTPGMGGMSGHGQHGNRPAPAALAAADALPAGAPLAALRT
LANESREPGTFRATLIAQPVARPLLRGARPTTFWQFGAGADGPVVGPLIDVREGDTVEIRFENKLPQPSTIHWHGLPVPP
DQDGNPSDAVAPGASRVYRFTLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDG
TIPPNDMMDWMNGREGQFVLVNGARRPRIEVAGDERWRVWNACSARYLRVAFDDGRAFEHVGTDGGLFGAPRRVTSLLLA
PGERAEMLVRAGDRASRAVLQAAEYDRGKMAMSHDDGHGSLPPDPARALADVVFAPAAPRGLPATLRTVPPLGEPVAHKE
VAFGEEMDMDAMMKAGAHGRPAGMRFTINGDTYAPGRVTLTSRRGDVERWTIRNATDMDHPFHLHGTQFQVIERATEGAR
TAEPFRAWRDTVNVRSGETVTILTTQDMAGERMFHCHILEHEDLGMMGTLKVV

Specific function: May be involved in copper homeostasis and oxidative stress response [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=470, Percent_Identity=31.2765957446809, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789394, Length=435, Percent_Identity=28.9655172413793, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR002355
- InterPro:   IPR008972 [H]

Pfam domain/function: PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 57723; Mature: 57723

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRTFLSRAIGVAAASLVARGAWAQHAGHAGMAGMDDMRDTPGMGGMSGHGQHGNRPAP
CCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
AALAAADALPAGAPLAALRTLANESREPGTFRATLIAQPVARPLLRGARPTTFWQFGAGA
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEEECCCCC
DGPVVGPLIDVREGDTVEIRFENKLPQPSTIHWHGLPVPPDQDGNPSDAVAPGASRVYRF
CCCEECCEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEE
TLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDG
ECCCCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHECCCC
TIPPNDMMDWMNGREGQFVLVNGARRPRIEVAGDERWRVWNACSARYLRVAFDDGRAFEH
CCCHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEEHHCCCEEEEEEECCCCEEEC
VGTDGGLFGAPRRVTSLLLAPGERAEMLVRAGDRASRAVLQAAEYDRGKMAMSHDDGHGS
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCC
LPPDPARALADVVFAPAAPRGLPATLRTVPPLGEPVAHKEVAFGEEMDMDAMMKAGAHGR
CCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCCC
PAGMRFTINGDTYAPGRVTLTSRRGDVERWTIRNATDMDHPFHLHGTQFQVIERATEGAR
CCCEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCEEECCCHHHHHHHHHCCCC
TAEPFRAWRDTVNVRSGETVTILTTQDMAGERMFHCHILEHEDLGMMGTLKVV
CHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MIRRTFLSRAIGVAAASLVARGAWAQHAGHAGMAGMDDMRDTPGMGGMSGHGQHGNRPAP
CCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCC
AALAAADALPAGAPLAALRTLANESREPGTFRATLIAQPVARPLLRGARPTTFWQFGAGA
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCCEEEECCCCC
DGPVVGPLIDVREGDTVEIRFENKLPQPSTIHWHGLPVPPDQDGNPSDAVAPGASRVYRF
CCCEECCEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEE
TLPKGSAGTYWYHPHPHMMTAEQVFRGLAGPFVVRAADDPLAGWPERHLFVSDLKLARDG
ECCCCCCCCEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCEEHHHHHECCCC
TIPPNDMMDWMNGREGQFVLVNGARRPRIEVAGDERWRVWNACSARYLRVAFDDGRAFEH
CCCHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEEHHCCCEEEEEEECCCCEEEC
VGTDGGLFGAPRRVTSLLLAPGERAEMLVRAGDRASRAVLQAAEYDRGKMAMSHDDGHGS
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCC
LPPDPARALADVVFAPAAPRGLPATLRTVPPLGEPVAHKEVAFGEEMDMDAMMKAGAHGR
CCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCCC
PAGMRFTINGDTYAPGRVTLTSRRGDVERWTIRNATDMDHPFHLHGTQFQVIERATEGAR
CCCEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCEEECCCHHHHHHHHHCCCC
TAEPFRAWRDTVNVRSGETVTILTTQDMAGERMFHCHILEHEDLGMMGTLKVV
CHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA