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The map label for this gene is xylB [H]

Identifier: 161523891

GI number: 161523891

Start: 780700

End: 782181

Strand: Reverse

Name: xylB [H]

Synonym: Bmul_0711

Alternate gene names: 161523891

Gene position: 782181-780700 (Counterclockwise)

Preceding gene: 161523892

Following gene: 161523890

Centisome position: 22.68

GC content: 71.86

Gene sequence:

>1482_bases
ATGTATCTCGGCATCGACCTCGGCACTTCGGAAGTGAAAGTGCTGCTGCTGGCCCCGGACGGCTCGGTCGTCGGCACGGC
CGGCACGCCGTTCACCGTATCGCGGCCGTATCCGCGCTGGGCCGAGCAGCATCCGGAAGACTGGTGGCAAGGCACGCTCA
CGGCGCTCGCGACGCTGCGCGAACGGCATCCGGACGCATTCGCGCAGGTGCGCGGCATCGGCCTGTCCGGCCAGATGCAC
GGCGCGGTGCTGCTCGGACGCGACGATCGCGTGCTGCGTCCGGCGATCCTCTGGAACGACATGCGCAGCGCCGACGAATG
CGCGCTGCTCACCGAGCGCGCCCCCGATCTGCATGCGCTCGCCGGCAATCTCGCGATGCCGGGATTCACCGCGCCGAAGC
TGCTCTGGGTCGCGAAGCACGAACCGCAGGTGTTCGCGGCGACGGCATGCGTGCTGATGCCGAAGGACTACCTGCGATTC
CGGCTGACCGGCGCGAAGGTGTCCGATCCGTCCGACGCGGCCGGCACGCTGTGGCTCGACGTCGCGCGCCGCGACTGGTC
CGACGCGCTGCTCGCCGCGTGCGACATGACGCGCGACCAGATGCCGCGCATCGTCGAAGGCAATGCGCCGTCCGGCACGC
TGCGCGCGGACGTCGCGCGCACGCTCGGGCTGTCCGAAGCGGTCGTCGTCGCGGGCGGCGGCGGCGACAACGCGACGAGC
GCGCTCGGCATCGGCGCGATCCATGCGGGCGATGGCTTCGTGTCGCTCGGCACGTCGGGCGTGCTGAGCGTCGTCGGCGA
TCGCTTCATGCCGAACCCCGCCTCGGCCGTGCACGCGTTCTGCCATGCGATCCCCGATCGCTGGCAACTGATGAGCGTCG
TGCTGTCGGCCGCGAGTTGCCTGCGCTGGGTCTGCAAGCTGACCGGCACCGACGAGCCCACACTGCTCGCCGAAGTCGAA
GCGCTCGACGCGGGCGCGCTCGCGACCGCGCCGCTGTTCCTGCCGTACCTGTCCGGCGAGCGCACGCCGCACAACGATCC
GTATGCGCAAGGCGTGTTCTTCGGGATGACGCATGCGACCGAGCGCGCGCATCTCGGCTACGCGGTGCTCGAAGGCGTGA
CGCTCGGCCTCGCGGACGGCCTCGACGCGCTGCATGCGGTCGGCGTCGAAACCGATCGGCTGTCGCTGATCGGCGGCGGC
GCGCGCAGCGCGTTCTGGGCGCAGTTGATCGCCGATGCGCTCAACGTCCGCACGCGCCGGCACGGCGGCGGCGAGACGGG
CGCCGCGCTCGGCGCCGCACGGCTCGGCTGGCTCGCGGTCGGCGCCGATCCCGAGGCCGTGCTGACCAAGCCGCCCGTGC
GCGCCGACTACACGCCGAACGCCGCGCGTCACGCGCTGCTGCGCGAGCGCCTGGACGCGTTCCGCGCGCTGTACCGTCAC
GTGCGTCCGCTTTACGAACCGTCGCGCACGCGTCTCGCGTGA

Upstream 100 bases:

>100_bases
CGGCCGGCCGCGGCGCGCGATGCGGGCGAACCGCCGTTGGCATGCGGCGGGCCGCGGGGCTAAAGTAGCGGCTCCTGACT
GACGGAACGGATCGCTATCT

Downstream 100 bases:

>100_bases
GCGGCCGCTGCCGCGCGGGTGCCGAACGGCGGCCCGCGCCGCATGCGGTACAGTGGATCCCGTTGCGCCGCACGCCGGCC
CGTTCCGAACCGAATCGCTA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MYLGIDLGTSEVKVLLLAPDGSVVGTAGTPFTVSRPYPRWAEQHPEDWWQGTLTALATLRERHPDAFAQVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHALAGNLAMPGFTAPKLLWVAKHEPQVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACDMTRDQMPRIVEGNAPSGTLRADVARTLGLSEAVVVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPTLLAEVE
ALDAGALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGLADGLDALHAVGVETDRLSLIGGG
ARSAFWAQLIADALNVRTRRHGGGETGAALGAARLGWLAVGADPEAVLTKPPVRADYTPNAARHALLRERLDAFRALYRH
VRPLYEPSRTRLA

Sequences:

>Translated_493_residues
MYLGIDLGTSEVKVLLLAPDGSVVGTAGTPFTVSRPYPRWAEQHPEDWWQGTLTALATLRERHPDAFAQVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHALAGNLAMPGFTAPKLLWVAKHEPQVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACDMTRDQMPRIVEGNAPSGTLRADVARTLGLSEAVVVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPTLLAEVE
ALDAGALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGLADGLDALHAVGVETDRLSLIGGG
ARSAFWAQLIADALNVRTRRHGGGETGAALGAARLGWLAVGADPEAVLTKPPVRADYTPNAARHALLRERLDAFRALYRH
VRPLYEPSRTRLA
>Mature_493_residues
MYLGIDLGTSEVKVLLLAPDGSVVGTAGTPFTVSRPYPRWAEQHPEDWWQGTLTALATLRERHPDAFAQVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHALAGNLAMPGFTAPKLLWVAKHEPQVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACDMTRDQMPRIVEGNAPSGTLRADVARTLGLSEAVVVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPTLLAEVE
ALDAGALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHATERAHLGYAVLEGVTLGLADGLDALHAVGVETDRLSLIGGG
ARSAFWAQLIADALNVRTRRHGGGETGAALGAARLGWLAVGADPEAVLTKPPVRADYTPNAARHALLRERLDAFRALYRH
VRPLYEPSRTRLA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=437, Percent_Identity=21.9679633867277, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4504007, Length=437, Percent_Identity=22.1967963386728, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI189409120, Length=437, Percent_Identity=22.1967963386728, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI41393575, Length=409, Percent_Identity=22.0048899755501, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI1789987, Length=489, Percent_Identity=52.760736196319, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1790005, Length=492, Percent_Identity=26.4227642276423, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789168, Length=455, Percent_Identity=27.6923076923077, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790361, Length=478, Percent_Identity=23.0125523012552, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1787789, Length=371, Percent_Identity=24.7978436657682, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=457, Percent_Identity=23.8512035010941, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321633, Length=335, Percent_Identity=25.6716417910448, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657106, Length=467, Percent_Identity=22.6980728051392, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24657102, Length=467, Percent_Identity=22.6980728051392, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52450; Mature: 52450

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDLGTSEVKVLLLAPDGSVVGTAGTPFTVSRPYPRWAEQHPEDWWQGTLTALATLR
CEEEEECCCCCEEEEEECCCCCEEECCCCCEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
ERHPDAFAQVRGIGLSGQMHGAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHAL
HHCCCHHHHHHCCCCCCCCCCEEEECCCCCEECHHHHHHCCCCCHHHHHHHCCCCCHHHH
AGNLAMPGFTAPKLLWVAKHEPQVFAATACVLMPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCEEEEEECCCCCEEEEHHHEECCCHHEEEEEECCCCCCCCCCCCEEEEE
VARRDWSDALLAACDMTRDQMPRIVEGNAPSGTLRADVARTLGLSEAVVVAGGGGDNATS
EHHCCHHHHHHHHHHCCHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCH
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASC
HHEEEEEECCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRWVCKLTGTDEPTLLAEVEALDAGALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHC
ERAHLGYAVLEGVTLGLADGLDALHAVGVETDRLSLIGGGARSAFWAQLIADALNVRTRR
HHHHCCHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
HGGGETGAALGAARLGWLAVGADPEAVLTKPPVRADYTPNAARHALLRERLDAFRALYRH
CCCCCCHHHHHHHHHCEEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRPLYEPSRTRLA
HHHCCCCCCCCCC
>Mature Secondary Structure
MYLGIDLGTSEVKVLLLAPDGSVVGTAGTPFTVSRPYPRWAEQHPEDWWQGTLTALATLR
CEEEEECCCCCEEEEEECCCCCEEECCCCCEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
ERHPDAFAQVRGIGLSGQMHGAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHAL
HHCCCHHHHHHCCCCCCCCCCEEEECCCCCEECHHHHHHCCCCCHHHHHHHCCCCCHHHH
AGNLAMPGFTAPKLLWVAKHEPQVFAATACVLMPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCEEEEEECCCCCEEEEHHHEECCCHHEEEEEECCCCCCCCCCCCEEEEE
VARRDWSDALLAACDMTRDQMPRIVEGNAPSGTLRADVARTLGLSEAVVVAGGGGDNATS
EHHCCHHHHHHHHHHCCHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCH
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASC
HHEEEEEECCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRWVCKLTGTDEPTLLAEVEALDAGALATAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHC
ERAHLGYAVLEGVTLGLADGLDALHAVGVETDRLSLIGGGARSAFWAQLIADALNVRTRR
HHHHCCHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
HGGGETGAALGAARLGWLAVGADPEAVLTKPPVRADYTPNAARHALLRERLDAFRALYRH
CCCCCCHHHHHHHHHCEEEECCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRPLYEPSRTRLA
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]