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The map label for this gene is erg3 [H]

Identifier: 161523858

GI number: 161523858

Start: 741916

End: 742830

Strand: Reverse

Name: erg3 [H]

Synonym: Bmul_0678

Alternate gene names: 161523858

Gene position: 742830-741916 (Counterclockwise)

Preceding gene: 161523859

Following gene: 161523857

Centisome position: 21.54

GC content: 64.92

Gene sequence:

>915_bases
ATGCGATTCGACGTCGAATGGCTTCTGCTCGCGCTGGCGCCCGTCTTCCTGCTCTGCATCGGCTGGGAGGCGTGGTACCT
CGCACGCACGCGTCCGCAGGACCACGTATACGCATGGCGCGACACGCTCTGCAATGCGGCGCTCGCGCTGATGCATCAGG
GCGCCGACAAGCTCGCCTGGGTGTTCGTGATTCCCGTCTACGCATACTGCTACGACCGCTATCGCCTGTTCACCTGGCAC
GACGGCTGGCTGTCGTTCGCGGTGCTGTTCGTCGCGCAGGACCTTCTCTACTACGTGTTTCATCGCGCGAGCCATCGCGT
GCGCTGGCTGTGGGCCGCGCACGTCGTGCATCACTCGTCCGAGCGGATGAACTTCTCGACCGCATTTCGCCAGAGCCTCA
TGTATCCGGTCGCCGGCATGTGGGTGTTCTGGCTGCCGCTCGCGCTGCTCGGCTTTCCGCCGCAGCAGATCGTCGGCGTC
GTGCTGATCAATCTCGCGTTCCAGTTCTTCGTGCACACGCAGGCGATCGGCAAGCTCGGCTGGCTCGAATACGTGTTCAA
CACGCCGTCGATCCATCGCGCGCACCATGCGCGCAACGCGCGCTACATCGACCGCAATTACGCGGGCGTGCTCGTGATCT
GGGATCGCCTGTTCGGCAGCTATGTCGACGAGGCGCCCGACGATCCGCCGCAGTACGGCATCGTCGAGCGGCTCGAGTCG
AACAACCCGCTCGTCGCGACGTTTCACGAATGGCGCGCGATGGCGGCCGACGCACTGCGCGTCGAGGGATGGCGCAACAA
ATTGCGCGCGATCGTCGGCCCGCCCGAGTGGGCAAGCGCTTATCATGCGCAGATCGGCGACACGGCCGATCGCGATCCGC
GCCGCGCACCGCTAGCCGGCGTACACAACGAATAA

Upstream 100 bases:

>100_bases
CTAGCCGGTGGCGATTGCGTAGGCTGTTGGCCTGACCGATATCTACAACGGGCGACACGCCCGGCCTCACGGCTTGCAGG
GGAAAGGAGGAGACACGCCC

Downstream 100 bases:

>100_bases
TCCATTTCAGCCAACGGCCGTCGCGCAGCCCGAACCTGAGCGGGCATGCGCAAACATGCAAGGCCATATCTACGAGGAGA
TCGATCGATGCAAACACAAC

Product: fatty acid hydroxylase

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRFDVEWLLLALAPVFLLCIGWEAWYLARTRPQDHVYAWRDTLCNAALALMHQGADKLAWVFVIPVYAYCYDRYRLFTWH
DGWLSFAVLFVAQDLLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWVFWLPLALLGFPPQQIVGV
VLINLAFQFFVHTQAIGKLGWLEYVFNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVDEAPDDPPQYGIVERLES
NNPLVATFHEWRAMAADALRVEGWRNKLRAIVGPPEWASAYHAQIGDTADRDPRRAPLAGVHNE

Sequences:

>Translated_304_residues
MRFDVEWLLLALAPVFLLCIGWEAWYLARTRPQDHVYAWRDTLCNAALALMHQGADKLAWVFVIPVYAYCYDRYRLFTWH
DGWLSFAVLFVAQDLLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWVFWLPLALLGFPPQQIVGV
VLINLAFQFFVHTQAIGKLGWLEYVFNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVDEAPDDPPQYGIVERLES
NNPLVATFHEWRAMAADALRVEGWRNKLRAIVGPPEWASAYHAQIGDTADRDPRRAPLAGVHNE
>Mature_304_residues
MRFDVEWLLLALAPVFLLCIGWEAWYLARTRPQDHVYAWRDTLCNAALALMHQGADKLAWVFVIPVYAYCYDRYRLFTWH
DGWLSFAVLFVAQDLLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWVFWLPLALLGFPPQQIVGV
VLINLAFQFFVHTQAIGKLGWLEYVFNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVDEAPDDPPQYGIVERLES
NNPLVATFHEWRAMAADALRVEGWRNKLRAIVGPPEWASAYHAQIGDTADRDPRRAPLAGVHNE

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=214, Percent_Identity=40.6542056074766, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25144659, Length=282, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35364; Mature: 35364

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDVEWLLLALAPVFLLCIGWEAWYLARTRPQDHVYAWRDTLCNAALALMHQGADKLAW
CCCCHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
VFVIPVYAYCYDRYRLFTWHDGWLSFAVLFVAQDLLYYVFHRASHRVRWLWAAHVVHHSS
HHHHHHHHHHHHCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCH
ERMNFSTAFRQSLMYPVAGMWVFWLPLALLGFPPQQIVGVVLINLAFQFFVHTQAIGKLG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLEYVFNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVDEAPDDPPQYGIVERLES
HHHHHHCCCCHHHHHHHCCCCEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCHHHHHHCC
NNPLVATFHEWRAMAADALRVEGWRNKLRAIVGPPEWASAYHAQIGDTADRDPRRAPLAG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC
VHNE
CCCC
>Mature Secondary Structure
MRFDVEWLLLALAPVFLLCIGWEAWYLARTRPQDHVYAWRDTLCNAALALMHQGADKLAW
CCCCHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
VFVIPVYAYCYDRYRLFTWHDGWLSFAVLFVAQDLLYYVFHRASHRVRWLWAAHVVHHSS
HHHHHHHHHHHHCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCH
ERMNFSTAFRQSLMYPVAGMWVFWLPLALLGFPPQQIVGVVLINLAFQFFVHTQAIGKLG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLEYVFNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVDEAPDDPPQYGIVERLES
HHHHHHCCCCHHHHHHHCCCCEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCHHHHHHCC
NNPLVATFHEWRAMAADALRVEGWRNKLRAIVGPPEWASAYHAQIGDTADRDPRRAPLAG
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC
VHNE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]