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The map label for this gene is gmhB [H]

Identifier: 161523776

GI number: 161523776

Start: 651381

End: 651944

Strand: Reverse

Name: gmhB [H]

Synonym: Bmul_0596

Alternate gene names: 161523776

Gene position: 651944-651381 (Counterclockwise)

Preceding gene: 161523777

Following gene: 161523775

Centisome position: 18.91

GC content: 67.38

Gene sequence:

>564_bases
ATGCCGACCAGCCCCAACCGCAAGCTCGTCGTCCTCGATCGCGACGGCGTGATCAACGTCGATTCGGACGCGTTCATCAA
GACGCCCGACGAGTGGATCGCGCTGCCCGGCGCGTTCGAGGCGATCGCACGGCTGAACCATGCCGGCTATCGCGTGGTCG
TCGCGACCAACCAGTCCGGCATCGGCCGCGGGCTGTTCGACATGGCCGCGCTCAACGCGATGCATCTGAAGATGCATCGC
GCGGCGGCCGCAGTCGGCGCGCGCATCGACGCGGTGTTCTTCTGCCCGCACACGTCCGAGGATCACTGCGAGTGCCGCAA
GCCGAAGCCCGGCATGATGCAGATGATCGCCGAGCGTTTCGAGATCGATCCCGATCACACGCCGGTCGTCGGCGATACGC
TGCGCGACCTGCTGGCCGGCGTCGCGGTCGGCTTCCAGCCGCACCTCGTGCTGACCGGCAAGGGCAAGAAGACGCTCGCC
GCGGGCGGGCTGCCGCCGGGCACGAAGGTCCACGACGACCTGCGTGCGTTCGCGCTCGATTTCCTTTCACACGACTACGA
GTGA

Upstream 100 bases:

>100_bases
CCGGCGCTGCGCGCGAACCGTCTGGCGCTGCTGTCCGCCCTGCATCAGCAGATGAACTGCGTCGCCGACATCTCGAAGCT
CGCCGCATAAGGGCCGCACG

Downstream 100 bases:

>100_bases
TGCGGCCGCCGCGCGCATCCTCCCCAACGCTACACTCACGCCGATGCGCTTCGTCCGTTCGCTGCTGCTGCTGATCTATT
TCATCGTGTACACGGTGCCG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGAFEAIARLNHAGYRVVVATNQSGIGRGLFDMAALNAMHLKMHR
AAAAVGARIDAVFFCPHTSEDHCECRKPKPGMMQMIAERFEIDPDHTPVVGDTLRDLLAGVAVGFQPHLVLTGKGKKTLA
AGGLPPGTKVHDDLRAFALDFLSHDYE

Sequences:

>Translated_187_residues
MPTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGAFEAIARLNHAGYRVVVATNQSGIGRGLFDMAALNAMHLKMHR
AAAAVGARIDAVFFCPHTSEDHCECRKPKPGMMQMIAERFEIDPDHTPVVGDTLRDLLAGVAVGFQPHLVLTGKGKKTLA
AGGLPPGTKVHDDLRAFALDFLSHDYE
>Mature_186_residues
PTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGAFEAIARLNHAGYRVVVATNQSGIGRGLFDMAALNAMHLKMHRA
AAAVGARIDAVFFCPHTSEDHCECRKPKPGMMQMIAERFEIDPDHTPVVGDTLRDLLAGVAVGFQPHLVLTGKGKKTLAA
GGLPPGTKVHDDLRAFALDFLSHDYE

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=153, Percent_Identity=35.9477124183007, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87082027, Length=141, Percent_Identity=30.4964539007092, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20264; Mature: 20132

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGAFEAIARLNHAGYRVVVATNQSG
CCCCCCCEEEEEECCCEEEECCCCEEECCHHHEECCHHHHHHHHHCCCCEEEEEEECCCC
IGRGLFDMAALNAMHLKMHRAAAAVGARIDAVFFCPHTSEDHCECRKPKPGMMQMIAERF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
EIDPDHTPVVGDTLRDLLAGVAVGFQPHLVLTGKGKKTLAAGGLPPGTKVHDDLRAFALD
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHH
FLSHDYE
HHHCCCC
>Mature Secondary Structure 
PTSPNRKLVVLDRDGVINVDSDAFIKTPDEWIALPGAFEAIARLNHAGYRVVVATNQSG
CCCCCCEEEEEECCCEEEECCCCEEECCHHHEECCHHHHHHHHHCCCCEEEEEEECCCC
IGRGLFDMAALNAMHLKMHRAAAAVGARIDAVFFCPHTSEDHCECRKPKPGMMQMIAERF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
EIDPDHTPVVGDTLRDLLAGVAVGFQPHLVLTGKGKKTLAAGGLPPGTKVHDDLRAFALD
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHH
FLSHDYE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919; 12101286 [H]