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The map label for this gene is plsC [H]

Identifier: 161523775

GI number: 161523775

Start: 650573

End: 651337

Strand: Reverse

Name: plsC [H]

Synonym: Bmul_0595

Alternate gene names: 161523775

Gene position: 651337-650573 (Counterclockwise)

Preceding gene: 161523776

Following gene: 161523774

Centisome position: 18.89

GC content: 64.44

Gene sequence:

>765_bases
ATGCGCTTCGTCCGTTCGCTGCTGCTGCTGATCTATTTCATCGTGTACACGGTGCCGTATGCGACCGCATGCTTCATCGC
GTTCCCGTTCCTGCGCCCCGACGCGCGCTACTGGATGGCGGCCGGCTGGTGCAAGTCGACGCTCTGGGTCGTGCGCTGGC
TGAACGGCATCCGCTACCGGATCGAAGGGTTCGAGAACCTGCCGGACGGTCCGGCCGTGCTGCTGTCCAAACACCAGTCG
GCGTGGGAGACGCTCGCGTTTCCGGCGCTGATGCCCAAGCCGCTTTGCTACGTGTTCAAGCGCGAGCTGCTGTACGTGCC
GTTCTTCGGCTGGGCGCTCGGCATGCTGCACATGGTCCACATCAACCGCAAGGAAGGCAAACACGCGTTCGATTCGGTGA
TCCGGCAGGGCAAGAAGCGTCTCACCGAAGGCGCGTGGGTGATCATGTTCCCCGAAGGCACGCGCACGCCGGTCGGCAAG
CAGGGCAAGTACAAGACGGGCGGCGCGCGCTTCGCGATCGAAACCGGCACCGCCGTCGTGCCGATCGCGCACAATGCCGG
TCATGTATGGCCGCGCAACTCGTTCACGAAGTATCCGGGCGTCGTCACGGTATCGATCGGCAAGCCGATCGACGTGACGG
GCCTCACGCCCGACGTATTGAACTCGCGCGTCGAAGCGTGGATCGAAGCGGAAATGCGCCGCATCGATCCCGATGCCTAT
CGACAGGCGGGCAACGCCGACACGCGCGACGCGGCACGTGTCTGA

Upstream 100 bases:

>100_bases
GTCCACGACGACCTGCGTGCGTTCGCGCTCGATTTCCTTTCACACGACTACGAGTGATGCGGCCGCCGCGCGCATCCTCC
CCAACGCTACACTCACGCCG

Downstream 100 bases:

>100_bases
TTCGTCCGGACAGCCGCCGTTGCGTACGACAAAACGAAGCGAACTGATGAAGAAGCGTCCGCGGCCACGACCCGCCGTCG
TGGCACTCGATCATCGCCAG

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRFVRSLLLLIYFIVYTVPYATACFIAFPFLRPDARYWMAAGWCKSTLWVVRWLNGIRYRIEGFENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKEGKHAFDSVIRQGKKRLTEGAWVIMFPEGTRTPVGK
QGKYKTGGARFAIETGTAVVPIAHNAGHVWPRNSFTKYPGVVTVSIGKPIDVTGLTPDVLNSRVEAWIEAEMRRIDPDAY
RQAGNADTRDAARV

Sequences:

>Translated_254_residues
MRFVRSLLLLIYFIVYTVPYATACFIAFPFLRPDARYWMAAGWCKSTLWVVRWLNGIRYRIEGFENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKEGKHAFDSVIRQGKKRLTEGAWVIMFPEGTRTPVGK
QGKYKTGGARFAIETGTAVVPIAHNAGHVWPRNSFTKYPGVVTVSIGKPIDVTGLTPDVLNSRVEAWIEAEMRRIDPDAY
RQAGNADTRDAARV
>Mature_254_residues
MRFVRSLLLLIYFIVYTVPYATACFIAFPFLRPDARYWMAAGWCKSTLWVVRWLNGIRYRIEGFENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGMLHMVHINRKEGKHAFDSVIRQGKKRLTEGAWVIMFPEGTRTPVGK
QGKYKTGGARFAIETGTAVVPIAHNAGHVWPRNSFTKYPGVVTVSIGKPIDVTGLTPDVLNSRVEAWIEAEMRRIDPDAY
RQAGNADTRDAARV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=196, Percent_Identity=29.0816326530612, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI15100175, Length=196, Percent_Identity=29.0816326530612, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI6041665, Length=174, Percent_Identity=27.0114942528736, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1789395, Length=182, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=206, Percent_Identity=25.7281553398058, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364648, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582856, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582854, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28805; Mature: 28805

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVRSLLLLIYFIVYTVPYATACFIAFPFLRPDARYWMAAGWCKSTLWVVRWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
IEGFENLPDGPAVLLSKHQSAWETLAFPALMPKPLCYVFKRELLYVPFFGWALGMLHMVH
ECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
INRKEGKHAFDSVIRQGKKRLTEGAWVIMFPEGTRTPVGKQGKYKTGGARFAIETGTAVV
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCEEE
PIAHNAGHVWPRNSFTKYPGVVTVSIGKPIDVTGLTPDVLNSRVEAWIEAEMRRIDPDAY
EEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHH
RQAGNADTRDAARV
HHCCCCCCCHHCCC
>Mature Secondary Structure
MRFVRSLLLLIYFIVYTVPYATACFIAFPFLRPDARYWMAAGWCKSTLWVVRWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
IEGFENLPDGPAVLLSKHQSAWETLAFPALMPKPLCYVFKRELLYVPFFGWALGMLHMVH
ECCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
INRKEGKHAFDSVIRQGKKRLTEGAWVIMFPEGTRTPVGKQGKYKTGGARFAIETGTAVV
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCEEE
PIAHNAGHVWPRNSFTKYPGVVTVSIGKPIDVTGLTPDVLNSRVEAWIEAEMRRIDPDAY
EEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHH
RQAGNADTRDAARV
HHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]