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The map label for this gene is ggt [H]

Identifier: 161523602

GI number: 161523602

Start: 461467

End: 463413

Strand: Reverse

Name: ggt [H]

Synonym: Bmul_0422

Alternate gene names: 161523602

Gene position: 463413-461467 (Counterclockwise)

Preceding gene: 161523603

Following gene: 161523598

Centisome position: 13.44

GC content: 70.16

Gene sequence:

>1947_bases
ATGACAATCGGCGCGCCGCGCGGCGACAATAGCGCGCCCGCCGCCTCCTTCGACTTCATTGCTGCAGAGGGTTCCATGTT
CGACCGGCTTCGTCCGTCTTCGCGTCCGTGGACGCTGATCGCCGCCATCGCGCTCGTCGCGTTCAATGCCGCCTGCACGT
CGCCTGCCACGCCGCCCGCCGCGGTCGTGCCCGTTGCCGCCTCGGGCGCCGCTGCGCCGCTGCCCGGCATGCACGCGCCC
GAACTCGCGACCGGCTGGACCGACAAGCCGGGCTGGACCGCGCAGCACTACATGATCGCGGCCGCGAATCCGCTTGCGAC
GCAGGCCGGCTACGAGATGCTGAAGGCCGGCGGCACCGCGGTCGATGCGGCGATCGCGACGCAGATGGTGCTCGCGCTCG
TCGAGCCGCAGTCGTCCGGCATCGGCGGCGGCGCGTTCATGCTGTACTTCGACGGCAAGACGACGCAGGCGTACGACGGC
CGCGAAACGGCGCCGGCCGCCGCGACCGACCGCCTGTTCTACGGCCCGACCGGCCAGCCGATGAGCTTCTACGAAGGCGT
CGTCGGCGGGCGCTCGGTCGGCACGCCCGGTGTGCTGCGCATGCTCGAGGCCGCGCATCGTGCGAACGGCAAGCTGCCGT
GGCGGCGGCTGTTCCAGCCGGCGATCCGGCTCGCCGAGCATGGTTTCACGATCAGCCCGCGGCTCGCGACGCTGATCGCG
AACGATCGCTATCTCATGAACGATCCGGCCGCGCGCGCGTACTTCTACAACAAGGACGGCACACCGAAGGCGGCCGGCAC
CGTGCTGAAGAACCCGGCGCTCGCGGCCGTGCTGCGGCAGGTCGCCGATCGCGGCGCGAACGCGTTCTACACCGGCGCGA
TCGCGCGCGACATCGTCGCGAAGGTGCGCAAGCACCCGACCAATCCGGGGCTGCTGTCGATGCAGGATCTCGCGCGCTAC
AAGGCGAAGGTGCGCGCGCCGCTGTGCGCCGACTACCGGCGCTCGATCGTCTGCGGGATGCCGCCGCCGTCGTCGGGCGG
GCTCGCGATCGCGCAGATGCTCGGCATCCTCGAGGCGATGCCCGACTGGCAGCAGATCGGCGCGCAGAAGCCGGTACGAA
ACGAGGTCGGCTACGAGCCGACGCCGTTCGCCGCGCACGTGTTCAGCGAAGCCGGGCGGCTCGCGTATGCGGATCGCGCG
CGCTACGTCGCCGATCCCGACTTCGTGCCGCTGCCGGGCGGCAAGTGGGCGAGCCTGATCGACAAGTCCTATCTCGCGCA
GCGCGCGCAACTGATCGGCGACAACAGCATGGGCGTCGCGCAGGCCGGCACGCCGCCGGGCGCGACGCTCGCGATGGCCG
ACGACCGCAGCCCGGAGCTGCCGTCGACGTCCGACATCGCGATCGTCGACCGCTACGGTCACGCGCTATCGATGACGACG
AGCATCGAAGATGCGTTCGGCTCGCGGCTGATGGTGCGCGGCTTCCTGCTCAACAACCAGCTCACCGACTTCTCGTTCGT
GTCGAGCGAGAACGGCCGGCCGGTCGCGAATCGCGTGCAGCCCGGCAAGCGGCCGCGCTCGGCGATGTCGCCGGAGCTCG
TGTTCGACAAGAAGACGAAGCAGGTGACGCTGATCGTCGGCTCGGCCGGCGGCCCCGCGATCATCAACCACGTCGCGAAG
GCGCTGGTCGGCGTGCTCGACTGGGGGATGACGATGCAGCAGGCGATCGCGCTGCCGAATTTCGGCTCGATGAACGGGCC
GACGCAGCTCGAACGCGGCCGCGTGTCGGACGCGCTCGTCGAAGGGCTCAAAGGCCGCGGGCACGATGTGCAGCTCGTCC
AGATGAATTCCGGGCTGCAGGGCATTCAGCGGTTGAACGTGCAGGGGCAGACGGTGTGGTTCGGCGGCGCCGATCCGCGG
CGGGAAGGCGTTGCGATGGGCGAGTGA

Upstream 100 bases:

>100_bases
TCACACGCGCGCGACCTCGACCTTCATAGAGTTCATCCTCGAACAGGCCGGAAAGACCGGCCGGCGCGGGCCCGACGCGC
TGCGTCAGGGTTCCTGACGG

Downstream 100 bases:

>100_bases
GCGGCCGCGCCGCGGCGACGCTTACGCCCGCCCCTTCCACGGCACCACGCGCCGCTCGATCCAGCGCATCGCGAGATCGA
ACAGCCACGCGATCGCACCG

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MTIGAPRGDNSAPAASFDFIAAEGSMFDRLRPSSRPWTLIAAIALVAFNAACTSPATPPAAVVPVAASGAAAPLPGMHAP
ELATGWTDKPGWTAQHYMIAAANPLATQAGYEMLKAGGTAVDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDG
RETAPAAATDRLFYGPTGQPMSFYEGVVGGRSVGTPGVLRMLEAAHRANGKLPWRRLFQPAIRLAEHGFTISPRLATLIA
NDRYLMNDPAARAYFYNKDGTPKAAGTVLKNPALAAVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSMQDLARY
KAKVRAPLCADYRRSIVCGMPPPSSGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFAAHVFSEAGRLAYADRA
RYVADPDFVPLPGGKWASLIDKSYLAQRAQLIGDNSMGVAQAGTPPGATLAMADDRSPELPSTSDIAIVDRYGHALSMTT
SIEDAFGSRLMVRGFLLNNQLTDFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDKKTKQVTLIVGSAGGPAIINHVAK
ALVGVLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALVEGLKGRGHDVQLVQMNSGLQGIQRLNVQGQTVWFGGADPR
REGVAMGE

Sequences:

>Translated_648_residues
MTIGAPRGDNSAPAASFDFIAAEGSMFDRLRPSSRPWTLIAAIALVAFNAACTSPATPPAAVVPVAASGAAAPLPGMHAP
ELATGWTDKPGWTAQHYMIAAANPLATQAGYEMLKAGGTAVDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDG
RETAPAAATDRLFYGPTGQPMSFYEGVVGGRSVGTPGVLRMLEAAHRANGKLPWRRLFQPAIRLAEHGFTISPRLATLIA
NDRYLMNDPAARAYFYNKDGTPKAAGTVLKNPALAAVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSMQDLARY
KAKVRAPLCADYRRSIVCGMPPPSSGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFAAHVFSEAGRLAYADRA
RYVADPDFVPLPGGKWASLIDKSYLAQRAQLIGDNSMGVAQAGTPPGATLAMADDRSPELPSTSDIAIVDRYGHALSMTT
SIEDAFGSRLMVRGFLLNNQLTDFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDKKTKQVTLIVGSAGGPAIINHVAK
ALVGVLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALVEGLKGRGHDVQLVQMNSGLQGIQRLNVQGQTVWFGGADPR
REGVAMGE
>Mature_647_residues
TIGAPRGDNSAPAASFDFIAAEGSMFDRLRPSSRPWTLIAAIALVAFNAACTSPATPPAAVVPVAASGAAAPLPGMHAPE
LATGWTDKPGWTAQHYMIAAANPLATQAGYEMLKAGGTAVDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDGR
ETAPAAATDRLFYGPTGQPMSFYEGVVGGRSVGTPGVLRMLEAAHRANGKLPWRRLFQPAIRLAEHGFTISPRLATLIAN
DRYLMNDPAARAYFYNKDGTPKAAGTVLKNPALAAVLRQVADRGANAFYTGAIARDIVAKVRKHPTNPGLLSMQDLARYK
AKVRAPLCADYRRSIVCGMPPPSSGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFAAHVFSEAGRLAYADRAR
YVADPDFVPLPGGKWASLIDKSYLAQRAQLIGDNSMGVAQAGTPPGATLAMADDRSPELPSTSDIAIVDRYGHALSMTTS
IEDAFGSRLMVRGFLLNNQLTDFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDKKTKQVTLIVGSAGGPAIINHVAKA
LVGVLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALVEGLKGRGHDVQLVQMNSGLQGIQRLNVQGQTVWFGGADPRR
EGVAMGE

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=557, Percent_Identity=30.3411131059246, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI73915090, Length=557, Percent_Identity=30.3411131059246, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI73915096, Length=557, Percent_Identity=30.3411131059246, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI73915094, Length=557, Percent_Identity=30.3411131059246, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI113429324, Length=556, Percent_Identity=29.4964028776978, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI113429326, Length=561, Percent_Identity=29.0552584670232, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI153266885, Length=571, Percent_Identity=28.7215411558669, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI153266901, Length=571, Percent_Identity=28.0210157618214, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI109148539, Length=533, Percent_Identity=27.9549718574109, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI153266907, Length=568, Percent_Identity=27.2887323943662, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI30581157, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI30581155, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI171543825, Length=175, Percent_Identity=33.7142857142857, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789856, Length=563, Percent_Identity=34.9911190053286, Blast_Score=270, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI72000294, Length=567, Percent_Identity=31.7460317460317, Blast_Score=226, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI212646519, Length=567, Percent_Identity=31.7460317460317, Blast_Score=225, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI193208245, Length=550, Percent_Identity=31.0909090909091, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193208247, Length=550, Percent_Identity=31.0909090909091, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17542894, Length=542, Percent_Identity=30.4428044280443, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17506189, Length=562, Percent_Identity=28.2918149466192, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI72001497, Length=235, Percent_Identity=27.6595744680851, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72001495, Length=235, Percent_Identity=27.6595744680851, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323330, Length=552, Percent_Identity=26.268115942029, Blast_Score=123, Evalue=9e-29,
Organism=Drosophila melanogaster, GI18859893, Length=557, Percent_Identity=30.7001795332136, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI45551474, Length=563, Percent_Identity=28.9520426287744, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24642670, Length=563, Percent_Identity=28.9520426287744, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24642666, Length=563, Percent_Identity=28.9520426287744, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI161077880, Length=563, Percent_Identity=28.9520426287744, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI161077878, Length=563, Percent_Identity=28.9520426287744, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI161077496, Length=528, Percent_Identity=27.0833333333333, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI18859741, Length=560, Percent_Identity=26.0714285714286, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 68550; Mature: 68419

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGAPRGDNSAPAASFDFIAAEGSMFDRLRPSSRPWTLIAAIALVAFNAACTSPATPPA
CCCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
AVVPVAASGAAAPLPGMHAPELATGWTDKPGWTAQHYMIAAANPLATQAGYEMLKAGGTA
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCH
VDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDGRETAPAAATDRLFYGPTGQP
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCC
MSFYEGVVGGRSVGTPGVLRMLEAAHRANGKLPWRRLFQPAIRLAEHGFTISPRLATLIA
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCHHEEEEE
NDRYLMNDPAARAYFYNKDGTPKAAGTVLKNPALAAVLRQVADRGANAFYTGAIARDIVA
CCCEEECCCCCEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
KVRKHPTNPGLLSMQDLARYKAKVRAPLCADYRRSIVCGMPPPSSGGLAIAQMLGILEAM
HHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHC
PDWQQIGAQKPVRNEVGYEPTPFAAHVFSEAGRLAYADRARYVADPDFVPLPGGKWASLI
CCHHHHCCCCCCHHHCCCCCCCHHHHHHHHCCCEEEHHCCCCCCCCCEEECCCCHHHHHH
DKSYLAQRAQLIGDNSMGVAQAGTPPGATLAMADDRSPELPSTSDIAIVDRYGHALSMTT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEEEC
SIEDAFGSRLMVRGFLLNNQLTDFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDKKTK
HHHHHHCCCEEHHEEECCCCCCCEEEECCCCCCCHHHHCCCCCCCCHHCCCCEEEECCCC
QVTLIVGSAGGPAIINHVAKALVGVLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALV
EEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHH
EGLKGRGHDVQLVQMNSGLQGIQRLNVQGQTVWFGGADPRREGVAMGE
HHHCCCCCCEEEEEECCCHHHHHHHCCCCCEEEECCCCCHHCCCCCCC
>Mature Secondary Structure 
TIGAPRGDNSAPAASFDFIAAEGSMFDRLRPSSRPWTLIAAIALVAFNAACTSPATPPA
CCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
AVVPVAASGAAAPLPGMHAPELATGWTDKPGWTAQHYMIAAANPLATQAGYEMLKAGGTA
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCH
VDAAIATQMVLALVEPQSSGIGGGAFMLYFDGKTTQAYDGRETAPAAATDRLFYGPTGQP
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCC
MSFYEGVVGGRSVGTPGVLRMLEAAHRANGKLPWRRLFQPAIRLAEHGFTISPRLATLIA
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCHHEEEEE
NDRYLMNDPAARAYFYNKDGTPKAAGTVLKNPALAAVLRQVADRGANAFYTGAIARDIVA
CCCEEECCCCCEEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
KVRKHPTNPGLLSMQDLARYKAKVRAPLCADYRRSIVCGMPPPSSGGLAIAQMLGILEAM
HHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHC
PDWQQIGAQKPVRNEVGYEPTPFAAHVFSEAGRLAYADRARYVADPDFVPLPGGKWASLI
CCHHHHCCCCCCHHHCCCCCCCHHHHHHHHCCCEEEHHCCCCCCCCCEEECCCCHHHHHH
DKSYLAQRAQLIGDNSMGVAQAGTPPGATLAMADDRSPELPSTSDIAIVDRYGHALSMTT
HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCEEEEEC
SIEDAFGSRLMVRGFLLNNQLTDFSFVSSENGRPVANRVQPGKRPRSAMSPELVFDKKTK
HHHHHHCCCEEHHEEECCCCCCCEEEECCCCCCCHHHHCCCCCCCCHHCCCCEEEECCCC
QVTLIVGSAGGPAIINHVAKALVGVLDWGMTMQQAIALPNFGSMNGPTQLERGRVSDALV
EEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHH
EGLKGRGHDVQLVQMNSGLQGIQRLNVQGQTVWFGGADPRREGVAMGE
HHHCCCCCCEEEEEECCCHHHHHHHCCCCCEEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA