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The map label for this gene is steT [H]

Identifier: 161509604

GI number: 161509604

Start: 1503969

End: 1505291

Strand: Reverse

Name: steT [H]

Synonym: USA300HOU_1374

Alternate gene names: 161509604

Gene position: 1505291-1503969 (Counterclockwise)

Preceding gene: 161509605

Following gene: 161509603

Centisome position: 52.4

GC content: 34.01

Gene sequence:

>1323_bases
ATGTCAAATGGTAAAGAATTACAAAAAAATATAGGTTTCTTCTCAGCGTTTGCTATTGTTATGGGGACAGTTATTGGTTC
AGGAGTATTCTTTAAAATATCAAACGTAACAGAAGTAACAGGAACAGCAGGAATGGCCTTGTTTGTATGGTTCCTAGGCG
GCATCATTACCATTTGTGCGGGGTTAACAGCAGCAGAACTTGCTGCTGCAATCCCTGAAACAGGTGGCTTAACGAAGTAT
ATAGAATATACATACGGTGATTTCTGGGGCTTCCTATCAGGTTGGGCGCAATCATTTATTTATTTTCCAGCTAACGTAGC
AGCATTGTCTATCGTATTTGCGACACAGCTAATTAATTTATTCCATTTATCTATAGGTTCGTTAATACCAATAGCAATCG
CATCTGCGTTATCTATTGTGTTGATAAATTTCCTAGGTTCAAAAGCAGGCGGAATTTTACAATCAGTTACTTTAGTAATT
AAACTGATTCCAATCATCGTTATTGTAATTTTTGGTATTTTTCAATCTGGAGATATCACTTTTTCATTAATTCCAACTAC
AGGTAATTCAGGAAATGGCTTCTTTACAGCAATTGGTAGTGGTTTATTAGCAACTATGTTTGCATATGATGGTTGGATTC
ATGTAGGAAATGTTGCGGGGGAACTTAAAAATCCTAAACGCGATTTACCTTTAGCGATTTCAGTTGGTATCGGTTGTATT
ATGGCTGTGTATTTATTAATTAACGCTACATTCTTATTAACGTTGCCAATAGAACTACTTGCTGGTAATTTAAATGCAGC
TTCAGATACATCAAAAATATTATTTGGTGAAAATGGCGGTAAGATTATTACAATCGGTATATTAATTTCTGTTTATGGTA
CGATCAATGGCTATACTATGACTGGTATGCGCGTACCATATGCAATGGCTGAAAGAAAATTATTGCCATTTAGCCATTTA
TTCGCAAAATTAACAAAATCTGGCGCACCATGGTTTGGCGCAATTATACAACTTATAATCGCTATCATCATGATGTCAAT
GGGAGCATTTGATACAATTACAAATATGTTAATCTTTGTTATTTGGTTGTTCTATTGTATGTCATTTGTTGCGGTAATAA
TTTTAAGAAAACGTGAACCAAATATGGAACGACCATATAAAGTACCGTTATATCCGATCATACCTTTAATTGCTATTTTG
GCAGGATCATTTGTATTAATTAATACACTGTTTACACAATTTATATTAGCAATCATTGGAATTCTAATAACAGCACTTGG
TATACCAGTTTATTACTATAAAAAGAAACAAAAAGCAGCATAA

Upstream 100 bases:

>100_bases
AACTAGAGTTTCAGGTGTCATTGAACATGGACTGAATATTGCAGATACAAGCAAGGGTGTGGTAGGTTAAAACATTTAAT
CTTAAAAATGAGGTGTAATT

Downstream 100 bases:

>100_bases
GGTAAGATAACTAGCATTGAGAATAAATGGATGGACTACTAATAAATTTAAAGTTTTACACATTAAAATCAAAAACCATT
CAATTATTCTATGGAACAGA

Product: APC family amino acid-polyamine-organocation transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAGMALFVWFLGGIITICAGLTAAELAAAIPETGGLTKY
IEYTYGDFWGFLSGWAQSFIYFPANVAALSIVFATQLINLFHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVI
KLIPIIVIVIFGIFQSGDITFSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNVAGELKNPKRDLPLAISVGIGCI
MAVYLLINATFLLTLPIELLAGNLNAASDTSKILFGENGGKIITIGILISVYGTINGYTMTGMRVPYAMAERKLLPFSHL
FAKLTKSGAPWFGAIIQLIIAIIMMSMGAFDTITNMLIFVIWLFYCMSFVAVIILRKREPNMERPYKVPLYPIIPLIAIL
AGSFVLINTLFTQFILAIIGILITALGIPVYYYKKKQKAA

Sequences:

>Translated_440_residues
MSNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAGMALFVWFLGGIITICAGLTAAELAAAIPETGGLTKY
IEYTYGDFWGFLSGWAQSFIYFPANVAALSIVFATQLINLFHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVI
KLIPIIVIVIFGIFQSGDITFSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNVAGELKNPKRDLPLAISVGIGCI
MAVYLLINATFLLTLPIELLAGNLNAASDTSKILFGENGGKIITIGILISVYGTINGYTMTGMRVPYAMAERKLLPFSHL
FAKLTKSGAPWFGAIIQLIIAIIMMSMGAFDTITNMLIFVIWLFYCMSFVAVIILRKREPNMERPYKVPLYPIIPLIAIL
AGSFVLINTLFTQFILAIIGILITALGIPVYYYKKKQKAA
>Mature_439_residues
SNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAGMALFVWFLGGIITICAGLTAAELAAAIPETGGLTKYI
EYTYGDFWGFLSGWAQSFIYFPANVAALSIVFATQLINLFHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVIK
LIPIIVIVIFGIFQSGDITFSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNVAGELKNPKRDLPLAISVGIGCIM
AVYLLINATFLLTLPIELLAGNLNAASDTSKILFGENGGKIITIGILISVYGTINGYTMTGMRVPYAMAERKLLPFSHLF
AKLTKSGAPWFGAIIQLIIAIIMMSMGAFDTITNMLIFVIWLFYCMSFVAVIILRKREPNMERPYKVPLYPIIPLIAILA
GSFVLINTLFTQFILAIIGILITALGIPVYYYKKKQKAA

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=450, Percent_Identity=30.2222222222222, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI187423910, Length=425, Percent_Identity=28.7058823529412, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI7657591, Length=425, Percent_Identity=28.7058823529412, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI71979932, Length=459, Percent_Identity=29.4117647058824, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI186910308, Length=438, Percent_Identity=25.5707762557078, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI186910306, Length=438, Percent_Identity=25.5707762557078, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI186910304, Length=438, Percent_Identity=25.5707762557078, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI115648063, Length=451, Percent_Identity=27.4944567627494, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI115648022, Length=451, Percent_Identity=27.4944567627494, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI7657683, Length=414, Percent_Identity=27.536231884058, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI9790235, Length=458, Percent_Identity=27.9475982532751, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI33286430, Length=242, Percent_Identity=30.9917355371901, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI71999149, Length=410, Percent_Identity=23.9024390243902, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4507047, Length=420, Percent_Identity=22.6190476190476, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI114326544, Length=420, Percent_Identity=22.1428571428571, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI114326550, Length=420, Percent_Identity=22.1428571428571, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082250, Length=446, Percent_Identity=26.457399103139, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI2367353, Length=361, Percent_Identity=27.1468144044321, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87081708, Length=453, Percent_Identity=23.3995584988962, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786908, Length=391, Percent_Identity=24.0409207161125, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786694, Length=385, Percent_Identity=22.8571428571429, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787890, Length=362, Percent_Identity=24.3093922651934, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788480, Length=447, Percent_Identity=24.6085011185682, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=445, Percent_Identity=28.9887640449438, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71982612, Length=442, Percent_Identity=25.7918552036199, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71982608, Length=442, Percent_Identity=25.7918552036199, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17568033, Length=450, Percent_Identity=25.1111111111111, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71990446, Length=452, Percent_Identity=24.3362831858407, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32566699, Length=402, Percent_Identity=27.363184079602, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI193208714, Length=432, Percent_Identity=24.0740740740741, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566695, Length=432, Percent_Identity=24.0740740740741, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71995388, Length=450, Percent_Identity=23.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71995382, Length=450, Percent_Identity=23.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71993915, Length=438, Percent_Identity=23.2876712328767, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982623, Length=266, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17532491, Length=398, Percent_Identity=25.1256281407035, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=401, Percent_Identity=23.9401496259352, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6321492, Length=351, Percent_Identity=23.9316239316239, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321751, Length=334, Percent_Identity=23.3532934131737, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21357367, Length=450, Percent_Identity=28, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24651635, Length=431, Percent_Identity=24.8259860788863, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24651633, Length=431, Percent_Identity=24.8259860788863, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45550968, Length=462, Percent_Identity=27.7056277056277, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19921172, Length=462, Percent_Identity=27.7056277056277, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24641993, Length=391, Percent_Identity=26.8542199488491, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24641995, Length=391, Percent_Identity=26.8542199488491, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI221331183, Length=446, Percent_Identity=28.2511210762332, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI17647653, Length=446, Percent_Identity=28.2511210762332, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24664379, Length=446, Percent_Identity=28.2511210762332, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24666159, Length=418, Percent_Identity=24.8803827751196, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221512776, Length=417, Percent_Identity=24.9400479616307, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47262; Mature: 47131

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAGMALFVWFLGGIITICA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHH
GLTAAELAAAIPETGGLTKYIEYTYGDFWGFLSGWAQSFIYFPANVAALSIVFATQLINL
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHH
FHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVIKLIPIIVIVIFGIFQSGDIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNVAGELKNPKRDLPLAISVGIGCI
EEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCEEECCHHHHCCCCCCCCCEEEHHHHHHH
MAVYLLINATFLLTLPIELLAGNLNAASDTSKILFGENGGKIITIGILISVYGTINGYTM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCCEEE
TGMRVPYAMAERKLLPFSHLFAKLTKSGAPWFGAIIQLIIAIIMMSMGAFDTITNMLIFV
ECCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IWLFYCMSFVAVIILRKREPNMERPYKVPLYPIIPLIAILAGSFVLINTLFTQFILAIIG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
ILITALGIPVYYYKKKQKAA
HHHHHHCCCCEEECCHHCCC
>Mature Secondary Structure 
SNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAGMALFVWFLGGIITICA
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHH
GLTAAELAAAIPETGGLTKYIEYTYGDFWGFLSGWAQSFIYFPANVAALSIVFATQLINL
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHH
FHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVIKLIPIIVIVIFGIFQSGDIT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNVAGELKNPKRDLPLAISVGIGCI
EEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCEEECCHHHHCCCCCCCCCEEEHHHHHHH
MAVYLLINATFLLTLPIELLAGNLNAASDTSKILFGENGGKIITIGILISVYGTINGYTM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHCCCCEEE
TGMRVPYAMAERKLLPFSHLFAKLTKSGAPWFGAIIQLIIAIIMMSMGAFDTITNMLIFV
ECCCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IWLFYCMSFVAVIILRKREPNMERPYKVPLYPIIPLIAILAGSFVLINTLFTQFILAIIG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
ILITALGIPVYYYKKKQKAA
HHHHHHCCCCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]