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The map label for this gene is cvfB

Identifier: 161509557

GI number: 161509557

Start: 1427241

End: 1428143

Strand: Reverse

Name: cvfB

Synonym: USA300HOU_1326

Alternate gene names: 161509557

Gene position: 1428143-1427241 (Counterclockwise)

Preceding gene: 161509567

Following gene: 161509556

Centisome position: 49.71

GC content: 35.11

Gene sequence:

>903_bases
ATGGCATTAGACAAAGATATAGTAGGTTCTATAGAATTCCTTGAAGTAGTAGGGTTACAAGGTTCAACTTACCTTTTAAA
AGGACCAAACGGTGAAAACGTAAAGTTAAACCAATCAGAAATGAACGATGATGATGAATTAGAAGTAGGTGAAGAATATA
GTTTCTTCATTTATCCAAACCGTTCAGGTGAATTATTTGCAACTCAAAATATGCCTGATATTACGAAAGATAAATATGAC
TTTGCTAAAGTACTTAAAACGGATCGCGATGGGGCACGTATAGATGTTGGATTACCCCGTGAAGTGTTAGTACCATGGGA
AGATTTACCAAAAGTGAAATCACTATGGCCACAACCTGGTGATTATTTGCTAGTTACATTACGAATTGACCGTGAGAATC
ATATGTATGGACGTTTAGCGAGTGAATCTGTTGTAGAAAATATGTTTACACCTGTACACGACGATAATTTAAAAAACGAA
GTCATTGAAGCCAAACCTTACCGCGTATTACGAATTGGTAGCTTTTTATTAAGCGAATCAGGTTACAAAATTTTCGTACA
TGAATCAGAACGTAAAGCTGAACCAAGATTAGGTGAATCTGTTCAAGTTAGAATTATCGGGCATAATGATAAAGGTGAGT
TAAATGGTTCATTTTTACCACTTGCACATGAACGTTTAGACGATGACGGCCAAGTCATCTTTGATTTACTAGTTGAATAT
GATGGTGAATTACCATTCTGGGACAAATCAAGCCCTGAAGCGATTAAAGAAGTATTCAATATGAGTAAAGGTTCATTCAA
ACGTGCAATCGGTCACTTATATAAACAGAAGATTATTAATATAGAAACAGGTAAAATCGCTTTAACTAAAAAAGGTTGGA
GTCGAATGGACTCAAAAGAATAA

Upstream 100 bases:

>100_bases
TCATATTATCGTCACAGTTTCGACCTCATATAAGTTGTAATGATAGAATGACTCACACATGTTATAATAATAAAGAATAC
AAGAATCGAAGGAGAATAAC

Downstream 100 bases:

>100_bases
TCATTTTTACACGTGTCGTAGGATGCGTGTTTTTTTTATTCAATATTAAATCGGACAGATGAAGTAGTTTTTTAAACATT
CCTTTCAAAGTAAAAAATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYD
FAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNE
VIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEY
DGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE

Sequences:

>Translated_300_residues
MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYD
FAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNE
VIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEY
DGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE
>Mature_299_residues
ALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDF
AKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEV
IEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEYD
GELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE

Specific function: Contributes to the expression of virulence factors and to pathogenicity. Involved in the production of hemolysin, DNase, protease and protein A

COG id: COG2996

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CvfB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CVFB_STAA3 (Q2FH47)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_493981.1
- ProteinModelPortal:   Q2FH47
- STRING:   Q2FH47
- EnsemblBacteria:   EBSTAT00000038367
- GeneID:   3913177
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1284
- eggNOG:   COG2996
- GeneTree:   EBGT00050000023979
- HOGENOM:   HBG313913
- OMA:   FKRALGH
- ProtClustDB:   CLSK885320
- GO:   GO:0009405
- InterPro:   IPR022967
- InterPro:   IPR014464
- PIRSF:   PIRSF012524
- SMART:   SM00316

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34199; Mature: 34068

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPN
CCCCCHHHCCEEEEEEECCCCCEEEEECCCCCCEEEEHHHCCCCCCEECCCCEEEEEEEC
RSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPG
CCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHEECCCHHCCHHHHHCCCCC
DYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEVIEAKPYRVLRIGSFLLSES
CEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEHHHHHCCC
GYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEY
CCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHC
DGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
ALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPN
CCCCHHHCCEEEEEEECCCCCEEEEECCCCCCEEEEHHHCCCCCCEECCCCEEEEEEEC
RSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPG
CCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHEECCCHHCCHHHHHCCCCC
DYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEVIEAKPYRVLRIGSFLLSES
CEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEEEEHHHHHCCC
GYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEY
CCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHC
DGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE
CCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEECCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA