Click here to switch to the map view.

The map label for this gene is plsB

Identifier: 161486422

GI number: 161486422

Start: 3435891

End: 3438314

Strand: Reverse

Name: plsB

Synonym: S3567

Alternate gene names: 161486422

Gene position: 3438314-3435891 (Counterclockwise)

Preceding gene: 161486420

Following gene: 30064625

Centisome position: 74.76

GC content: 55.16

Gene sequence:

>2424_bases
ATGTCCGGCTGGCCACGAATTTACTACAAATTACTGAATTTACCATTAAGCATCCTGGTAAAAAGCAAGTCTATTCCGGC
AGATCCTGCCCCGGAACTGGGGCTGGATACCTCTCGTCCAATTATGTACGTTTTACCGTACAACTCGAAAGCAGATTTGC
TGACGTTGCGCGCCCAGTGTCTGGCACATGATTTGCCTGACCCGTTAGAGCCGCTGGAAATCGACGGCACGCTACTGCCG
CGCTATGTGTTCATTCACGGCGGGCCGCGTGTATTCACCTATTACACGCCGAAAGAAGAGTCTATTAAGCTTTTCCACGA
CTATCTCGATTTGCACCGTAGCAACCCAAATCTGGATGTGCAGATGGTGCCAGTATCGGTGATGTTTGGTCGCGCGCCGG
GGCGTGAAAAAGGCGAAGTGAACCCGCCGCTGCGTATGCTTAACGGCGTACAGAAATTTTTCGCTGTACTGTGGCTCGGT
CGCGACAGTTTTGTGCGTTTCTCGCCGTCAGTGTCGCTGCGCCGTATGGCGGATGAACACGGCACGGATAAAACTATCGC
TCAGAAACTGGCGCGCGTGGCGCGTATGCACTTTGCCCGTCAACGTCTGGCTGCCGTAGGCCCACGTCTGCCTGCTCGTC
AGGATCTGTTTAATAAGCTGCTCGCCTCCCGCGCCATTGCCAAAGCGGTAGAAGATGAAGCGCGCAGCAAAAAAATCTCC
CATGAAAAAGCGCAGCAGAACGCGATTGCGCTGATGGAAGAGATTGCGGCGAATTTCTCTTACGAGATGATCCGCCTGAC
TGACCGCATTCTGGGCTTCACCTGGAACCGATTTTATCAGGGCATCAACGTCCATAACGCCGAGCGCGTTCGCCAGCTGG
CCCACGACGGTCATGAGCTGGTGTATGTGCCTTGCCACCGCAGTCACATGGACTACCTGCTACTTTCTTACGTGCTGTAC
CACCAGGGGCTGGTGCCGCCGCATATCGCCGCCGGGATCAACCTGAACTTCTGGCCGGCCGGGCCGATTTTCCGCCGTCT
GGGGGCGTTCTTTATTCGCCGTACTTTTAAAGGCAATAAACTTTATTCCACCGTTTTCCGTGAGTATCTCGGCGAACTGT
TCAGCCGTGGTTATTCCGTCGAGTACTTCGTGGAAGGCGGTCGTTCCCGCACGGGGCGTTTGCTGGATCCGAAAACCGGT
ACGCTGTCGATGACCATTCAGGCGATGCTGCGTGGCGGCACGCGTCCGATTACGCTGATTCCGATCTATATCGGTTATGA
GCACGTCATGGAAGTGGGTACTTACGCCAAAGAACTGCGCGGCGCGACGAAAGAGAAAGAGAGCCTGCCGCAGATGCTGC
GCGGTTTAAGCAAGCTGCGTAATCTCGGTCAGGGTTACGTCAACTTCGGTGAACCAATGCCGTTGATGACCTACCTTAAC
CAGCACGTACCAGACTGGCGTGAATCTATCGATCCCATCGAAGCGGTGCGTCCGGCCTGGTTAACGCCGACGGTCAATAA
TATTGCTGCCGATCTGATGGTACGCATTAACAACGCAGGCGCGGCAAACGCCATGAACCTGTGCTGTACTGCGCTACTGG
CATCACGTCAGCGCTCACTCACCCGCGAGCAGTTAACCGAGCAACTCAACTGCTACCTGGATCTGATGCGCAACGTACCT
TACTCCACGGACTCTACCGTTCCTTCAGCCAGCGCCAGCGAGCTTATCGATCACGCGCTGCAAATGAACAAGTTTGAAGT
CGAGAAAGACACTATCGGCGACATCATCATTCTGCCACGCGAGCAAGCGGTGCTGATGACCTACTATCGCAACAACATTG
CGCATATGTTGGTGCTGCCTTCGCTGATGGCGGCAATTGTCACCCAGCATCGCCACATCTCCCGCGACGTATTGATGGAG
CACGTCAATGTGCTTTACCCAATGCTGAAAGCGGAGCTGTTCCTGCGCTGGGATCGCGACGAGTTGCCGGACGTTATTGA
TGCGCTGGCAAATGAGATGCAACGTCAGGGGCTGATTACCCTGCAAGATGATGAGTTGCATATCAACCCGGCGCATTCTC
GCACCCTACAGCTGCTGGCCGCAGGCGCGCGCGAAACGCTGCAACGTTATGCCATCACCTTCTGGTTGTTGAGTGCCAAC
CCGTCGATCAACCGCGGTACGCTGGAGAAAGAGAGCCGCACCGTTGCGCAACGTCTCTCCGTGCTGCACGGCATCAACGC
GCCGGAGTTCTTCGACAAGGCGGTGTTCAGTTCTCTGGTGCTGACGCTGCGTGATGAAGGGTATATCAGCGATAGCGGCG
ATGCCGAACCAGCAGAAACGATGAAGGTTTATCAGTTGCTGGCGGAGTTGATTACATCAGACGTGCGTTTGACGATTGAG
AGTGCGACGCAGGGCGAAGGGTAA

Upstream 100 bases:

>100_bases
AACGCCGCGCGAAACATGAGCGGATACCACAGAATTTCCCATGACTTTCTGCTATCCTTGCCGCGCATTTGCATTATTAA
CCAGAGGCTTTACATCGTTT

Downstream 100 bases:

>100_bases
TCAGAGAGAATTGCCGGATGCGGCGAAAACGCCTTATCCGGCCTACCATGACCTGCAAATTCAATAAATTGCGATTCACC
GGGTAGGCCTGAGAAGCGCA

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLP
RYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKIS
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRFYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLY
HQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTG
TLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLN
QHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVP
YSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLME
HVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
PSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIE
SATQGEG

Sequences:

>Translated_807_residues
MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLP
RYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKIS
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRFYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLY
HQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTG
TLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLN
QHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVP
YSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLME
HVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
PSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIE
SATQGEG
>Mature_806_residues
SGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPR
YVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGR
DSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISH
EKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRFYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYH
QGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGT
LSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQ
HVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPY
STDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEH
VNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANP
SINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIES
ATQGEG

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=435, Percent_Identity=27.816091954023, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI190358539, Length=272, Percent_Identity=33.8235294117647, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI87082362, Length=807, Percent_Identity=99.8760842627014, Blast_Score=1664, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988723, Length=278, Percent_Identity=31.294964028777, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI25147672, Length=279, Percent_Identity=29.7491039426523, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71988728, Length=190, Percent_Identity=37.8947368421053, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24650754, Length=499, Percent_Identity=25.6513026052104, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI21357731, Length=499, Percent_Identity=25.6513026052104, Blast_Score=146, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24650752, Length=499, Percent_Identity=25.6513026052104, Blast_Score=146, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17864692, Length=270, Percent_Identity=30.7407407407407, Blast_Score=143, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 91417; Mature: 91286

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQC
CCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDV
HHCCCCCCCCCCCCCCEEECEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEE
QMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEH
EEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHC
GTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKIS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRFYQGINVHNAERVRQLAHDGHEL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNK
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLI
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLN
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSL
HCCCCHHHCCCHHHHCCCCCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHH
TREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEECC
EQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRD
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
ELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
HHHHHHHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECC
PSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAET
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MKVYQLLAELITSDVRLTIESATQGEG
HHHHHHHHHHHCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQC
CCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDV
HHCCCCCCCCCCCCCCEEECEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEE
QMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEH
EEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHC
GTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKIS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRFYQGINVHNAERVRQLAHDGHEL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNK
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLI
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLN
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSL
HCCCCHHHCCCHHHHCCCCCCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHH
TREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEECC
EQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRD
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
ELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSAN
HHHHHHHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHEEEEECC
PSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAET
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MKVYQLLAELITSDVRLTIESATQGEG
HHHHHHHHHHHCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA