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The map label for this gene is yjbK

Identifier: 161486420

GI number: 161486420

Start: 3441336

End: 3441851

Strand: Reverse

Name: yjbK

Synonym: S3572

Alternate gene names: 161486420

Gene position: 3441851-3441336 (Counterclockwise)

Preceding gene: 30064640

Following gene: 161486422

Centisome position: 74.83

GC content: 52.91

Gene sequence:

>516_bases
ATGGAAAAGACCACAACGCAGGAGTTATTAGCGCAGGCTGAAAAAATCTGCGCGCAGCGTAATGTGCGCCTGACCCCACA
GCGCCTGGAAGTGTTGCGCCTGATGAGTCTGCAGGATGGCGCTATCAGCGCTTATGATCTGCTTGATTTACTGCGCGAAG
CTGAACCGCAAGCCAAGCCGCCAACGGTTTATCGCGCGCTGGATTTTCTGCTTGAGCAAGGTTTTGTGCATAAGGTGGAA
TCCACCAACAGTTATGTGCTCTGTCATCTGTTCGACCAGCCCACGCATACGTCAGCCATGTTTATTTGCGATCGCTGCGG
CGCGGTGAAAGAAGAGTGTGCAGAAGGCGTGGAAGACATTATGCATACGCTGGCGGCAAAAATGGGGTTTGCCCTGCGGC
ATAATGTGATTGAAGCACATGGGCTCTGTGCGGCATGCGTGGAAGTGGAAGCGTGTCGTCATCCTGAACAGTGCCAGCAT
GATCACTCTGTGCAGGTGAAAAAGAAACCGCGTTAA

Upstream 100 bases:

>100_bases
AAACAGAAAATCAACATTACGGCAACAATAAGGGTTCTCGGTGTTTTTCCTGGAACATGGTAAAGTAAGGACATTCTTAA
CCCCCACTTTGAGGTGCCCG

Downstream 100 bases:

>100_bases
GAGGGCGTACATCCTTGTACACGTCGGGCAGGAGGGATTAATTACCAGCGATATTCATTGCGGGTTTCCCAATCCACGAC
CTCTTTTTCTGCCTGATCTT

Product: zinc uptake transcriptional repressor

Products: NA

Alternate protein names: Zinc uptake regulator

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKPR

Sequences:

>Translated_171_residues
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKPR
>Mature_171_residues
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKPR

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB)

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family

Homologues:

Organism=Escherichia coli, GI87082363, Length=171, Percent_Identity=100, Blast_Score=353, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZUR_ECOLI (P0AC51)

Other databases:

- EMBL:   U00006
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E65212
- RefSeq:   AP_004547.1
- RefSeq:   NP_418470.4
- ProteinModelPortal:   P0AC51
- SMR:   P0AC51
- STRING:   P0AC51
- EnsemblBacteria:   EBESCT00000001232
- EnsemblBacteria:   EBESCT00000017896
- GeneID:   948552
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5714
- KEGG:   eco:b4046
- EchoBASE:   EB1873
- EcoGene:   EG11929
- eggNOG:   COG0735
- GeneTree:   EBGT00050000009317
- HOGENOM:   HBG731501
- OMA:   SRPHDHS
- ProtClustDB:   PRK11639
- BioCyc:   EcoCyc:EG11929-MONOMER
- Genevestigator:   P0AC51
- InterPro:   IPR002481
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF01475 FUR

EC number: NA

Molecular weight: Translated: 19254; Mature: 19254

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKP
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
PTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDI
CHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
MHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQHDHSVQVKKKPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKP
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
PTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDI
CHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
MHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQHDHSVQVKKKPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209