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The map label for this gene is murG [H]

Identifier: 161378149

GI number: 161378149

Start: 1252461

End: 1253564

Strand: Reverse

Name: murG [H]

Synonym: SPy_1524

Alternate gene names: 161378149

Gene position: 1253564-1252461 (Counterclockwise)

Preceding gene: 15675424

Following gene: 15675422

Centisome position: 67.67

GC content: 41.21

Gene sequence:

>1104_bases
TTGTTTAAGAGGAGATGCCTAATGCCTAAGAAGATTTTATTTACAGGTGGTGGAACTGTAGGTCATGTCACCTTGAACCT
CATTCTCATACCAAAATTTATCAAGGACGGTTGGGAAGTACATTATATTGGTGATAAAAATGGCATTGAACATACAGAAA
TTGAAAAGTCAGGCCTTGACGTGACCTTTCATGCTATCGCGACAGGCAAGCTTAGACGCTATTTTTCATGGCAAAATCTA
GCTGATGTTTTTAAGGTTGCACTTGGCCTCCTACAGTCTCTCTTTATTGTTGCCAAGCTTCGCCCTCAAGCCCTTTTTTC
CAAAGGTGGTTTTGTCTCAGTACCGCCAGTTGTGGCTGCTAAATTGCTTGGTAAACCAGTCTTTATTCATGAATCAGATC
GGTCAATGGGACTAGCAAACAAGATTGCCTACAAATTTGCAACTACCATGTATACCACTTTTGAGCAGGAAGACCAGTTG
TCTAAAGTTAAACACCTTGGAGCGGTGACAAAGGTTTTCAAAGATGCCAACCAAATGCCTGAATCAACTCAGTTAGAGGC
GGTGAAAGAGTATTTTAGTAGAGACCTAAAAACCCTCTTGTTTATTGGTGGTTCGGCAGGGGCGCATGTGTTTAATCAGT
TTATTAGTGATCATCCAGAATTGAAGCAACGTTATAATATCATCAATATTACAGGAGACCCTCACCTTAATGAATTGAGT
TCTCATCTGTATCGAGTAGATTATGTTACCGATCTCTACCAACCTTTGATGGCGATGGCTGACCTTGTAGTGACAAGAGG
GGGCTCTAATACACTTTTTGAGCTACTGGCAATGGCTAAGCTACACCTCATCGTTCCTCTTGGTAAAGAAGCTAGCCGTG
GCGATCAGTTAGAAAATGCCACTTATTTTGAGAAGAGGGGCTACGCTAAACAATTACAGGAACCTGATTTAACTTTGCAT
AATTTTGATCAGGCAATGGCTGATTTGTTTGAACATCAGGCTGATTATGAGGCTACTATGTTGGCAACTAAGGAGATTCA
GTCACCGGACTTCTTTTATGACCTTTTGAGAGCTGATATTAGCTCCGCGATTAAGGAGAAGTAA

Upstream 100 bases:

>100_bases
CCCAAACAGGCGATACTATCTTGCTTAGCCCAGCCAATGCTAGCTGGGATATGTATCCTAATTTTGAGGTTCGTGGGGAT
GAATTTTTGGCAACCTTTGA

Downstream 100 bases:

>100_bases
ATGGCAAAAGATAAAGAGAAACAAAGTGATGACAAGCTCGTTTTGACAGAGTGGCAAAAGCGTAACATTGAATTTTTAAA
GAAAAAGAAGCAGCAAGCTG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLDVTFHAIATGKLRRYFSWQNL
ADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQL
SKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS
SHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLH
NFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK

Sequences:

>Translated_367_residues
MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLDVTFHAIATGKLRRYFSWQNL
ADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQL
SKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS
SHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLH
NFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK
>Mature_367_residues
MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLDVTFHAIATGKLRRYFSWQNL
ADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQL
SKVKHLGAVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS
SHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLH
NFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADISSAIKEK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=337, Percent_Identity=27.0029673590504, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 41355; Mature: 41355

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLD
CCCCCCCCCCEEEEECCCEEEEEEEEEEEEEHHHHCCCEEEEECCCCCCCCCHHHHCCCC
VTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHH
KLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLGAVTKVFKDANQMP
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS
CHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHHHH
SHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
TYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADI
HHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
SSAIKEK
HHHHCCC
>Mature Secondary Structure
MFKRRCLMPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEHTEIEKSGLD
CCCCCCCCCCEEEEECCCEEEEEEEEEEEEEHHHHCCCEEEEECCCCCCCCCHHHHCCCC
VTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKGGFVSVPPVVAA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHH
KLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLGAVTKVFKDANQMP
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRYNIINITGDPHLNELS
CHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHHCCEEEECCCCCHHHHH
SHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHLIVPLGKEASRGDQLENA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCC
TYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATMLATKEIQSPDFFYDLLRADI
HHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHH
SSAIKEK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]